GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
GUK1 |
FullNmae |
guanylate kinase 1 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:4693 |
EnsembleID |
ENSG00000143774 |
Uniprot |
Q16774 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
GUK1 |
autophagy |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
GUK1 |
GO:0001917,GO:0004385,GO:0004385,GO:0004385,GO:0004385,GO:0004385,GO:0005515,GO:0005524,GO:0005829,GO:0005829,GO:0005829,GO:0006163,GO:0006185,GO:0006805,GO:0006805,GO:0015949,GO:0016310,GO:0046037,GO:0046710 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
EGR1 |
GUK1 |
19374776
23180781
|
physical association |
anti tag coimmunoprecipitation |
InnateDB |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
E2F4 |
GUK1 |
17531812
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
ETS1 |
GUK1 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
YBX1 |
GUK1 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ZNF263 |
GUK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00000821E0 |
GUK1 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000759B6A |
GUK1 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002CBC6D |
GUK1 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000006372A |
GUK1 |
25416803
26701625
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
NDUFAF4 |
GUK1 |
24234451
25348397
27499296
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
NLGN3 |
GUK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
TTC19 |
GUK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
HNRNPD |
GUK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
IQCB1 |
GUK1 |
21565611
24234451
25348397
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
UBE2Z |
GUK1 |
19549727
24234451
25348397
|
physical association |
two hybrid |
ComPPI,IntAct |
NXF1 |
GUK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
MOV10 |
GUK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
HSPB2 |
GUK1 |
24234451
25348397
26465331
|
physical association |
two hybrid |
ComPPI,IntAct |
TMEM97 |
GUK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
NDUFA4 |
GUK1 |
25348397
|
N/A |
physical interaction |
ComPPI |
GUK1 |
DPY19L2 |
25348397
|
N/A |
physical interaction |
ComPPI |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00009AE226 |
GUK1 |
27087310
|
direct interaction,inhibition |
N/A |
NPInter |
Visualization