Gene Information gene info

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GENE：GUK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GUK1
FullNmae guanylate kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4693
EnsembleID ENSG00000143774
Uniprot Q16774

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GUK1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GUK1 GO:0001917,GO:0004385,GO:0004385,GO:0004385,GO:0004385,GO:0004385,GO:0005515,GO:0005524,GO:0005829,GO:0005829,GO:0005829,GO:0006163,GO:0006185,GO:0006805,GO:0006805,GO:0015949,GO:0016310,GO:0046037,GO:0046710

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GUK1 hsa:2987 path:hsa00230 Purine metabolism - Homo sapiens (human)
GUK1 hsa:2987 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GUK1 hsa:2987 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 GUK1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 GUK1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GUK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GUK1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 GUK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000821E0 GUK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000759B6A GUK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002CBC6D GUK1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006372A GUK1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NDUFAF4 GUK1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
NLGN3 GUK1 25348397 N/A physical interaction ComPPI
TTC19 GUK1 25348397 N/A physical interaction ComPPI
HNRNPD GUK1 25348397 N/A physical interaction ComPPI
IQCB1 GUK1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2Z GUK1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
NXF1 GUK1 25348397 N/A physical interaction ComPPI
MOV10 GUK1 25348397 N/A physical interaction ComPPI
HSPB2 GUK1 24234451 25348397 26465331 physical association two hybrid ComPPI,IntAct
TMEM97 GUK1 25348397 N/A physical interaction ComPPI
NDUFA4 GUK1 25348397 N/A physical interaction ComPPI
GUK1 DPY19L2 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009AE226 GUK1 27087310 direct interaction,inhibition N/A NPInter

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