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GENE：SH3BP4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SH3BP4
FullNmae SH3 domain binding protein 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10826
EnsembleID ENSG00000130147
Uniprot Q9P0V3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SH3BP4 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SH3BP4 lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SH3BP4 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SH3BP4 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SH3BP4 GO:0005092,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005905,GO:0006897,GO:0008285,GO:0010508,GO:0030136,GO:0030308,GO:0031267,GO:0032007,GO:0034260,GO:0042802,GO:0050790,GO:0061462,GO:0070062,GO:0071230

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SH3BP4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SH3BP4 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 SH3BP4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 SH3BP4 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SH3BP4 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SH3BP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 SH3BP4 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 SH3BP4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00000ED600 SH3BP4 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 SH3BP4 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 SH3BP4 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000600E6 SH3BP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 SH3BP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 SH3BP4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004DA9DB SH3BP4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 SH3BP4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 SH3BP4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F SH3BP4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004A6E26 SH3BP4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000059EB31 SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F SH3BP4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C3F6 SH3BP4 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FAM110A SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TFRC SH3BP4 16325581 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,surface plasmon resonance,physical interaction,competition binding ComPPI,IntAct
MRGBP SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
YWHAG SH3BP4 14525934 15324660 17353931 20936779 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid pooling approach,in vivo ComPPI,HPRD,IntAct
GIPC2 SH3BP4 25348397 N/A physical interaction ComPPI
CBY1 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF1 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YWHAB SH3BP4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
YWHAZ SH3BP4 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
TFAP2A SH3BP4 16325581 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MAGI1 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DNM1 SH3BP4 25348397 N/A physical interaction ComPPI
HSPA5 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMA1 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYC SH3BP4 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HNRNPL SH3BP4 25348397 N/A physical interaction ComPPI
GIPC1 SH3BP4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB3IP SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ATP6AP2 SH3BP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAQ SH3BP4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EPS15 SH3BP4 16325581 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MPHOSPH8 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SFN SH3BP4 15778465 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
YWHAE SH3BP4 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FKBP4 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TCP1 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TTC1 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3PXD2A SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NFU1 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDCD1 SH3BP4 25348397 N/A physical interaction ComPPI
TRIM25 SH3BP4 25348397 N/A physical interaction ComPPI
KIF13B SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDC25B SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CETN1 SH3BP4 25348397 N/A physical interaction ComPPI
ZNF638 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SIPA1L1 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3BP4 CIZ1 18654987 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SH3BP4 GKAP1 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3BP4 TXNL1 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3BP4 PLEKHA1 18654987 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SH3BP4 CCT3 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3BP4 PRR14 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3BP4 GAPDHS 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3BP4 VSIG4 25348397 N/A physical interaction ComPPI
SH3BP4 NTRK3 25348397 N/A physical interaction ComPPI
SH3BP4 TOR1AIP2 25348397 N/A physical interaction ComPPI
SH3BP4 IL13RA2 25348397 N/A physical interaction ComPPI
SH3BP4 USP21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3BP4 SRSF12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3BP4 LIMA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3BP4 EIF4E2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3BP4 LRFN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3BP4 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3BP4 DNM2 16325581 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
SH3BP4 TFRC 16325581 27898060 inhibition N/A OmniPath

Visualization










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