Gene Information gene info

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GENE：ATG4D

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATG4D
FullNmae autophagy related 4D cysteine peptidase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20789
EnsembleID ENSG00000130734
Uniprot Q86TL0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATG4D ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATG4D autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATG4D GO:0000423,GO:0005654,GO:0005739,GO:0005759,GO:0006508,GO:0006914,GO:0006915,GO:0008234,GO:0015031,GO:0019786,GO:0034497,GO:0051697

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATG4D hsa:84971 path:hsa04136 Autophagy - other - Homo sapiens (human)
ATG4D hsa:84971 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATG4D CASP3 19549685 23180781 cleavage reaction protease assay InnateDB
ATG4D CASP8 19549685 23180781 cleavage reaction protease assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ATG4D 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 ATG4D 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ATG4D 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATG4D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATG4D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATG4D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATG4D 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 ATG4D 25416803 26313360 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
GABARAPL2 ATG4D 25348397 N/A physical interaction ComPPI
CASP3 ATG4D 25348397 N/A physical interaction ComPPI
CASP8 ATG4D 25348397 N/A physical interaction ComPPI
GOPC ATG4D 25348397 N/A physical interaction ComPPI
P4HA2 ATG4D 25348397 N/A physical interaction ComPPI
GABARAPL1 ATG4D 25348397 N/A physical interaction ComPPI
IMPDH1 ATG4D 25348397 N/A physical interaction ComPPI
CASP3 ATG4D 19549685 27898060 stimulant N/A OmniPath
CASP8 ATG4D 19549685 27898060 N/A N/A OmniPath
ATG4D GABARAPL1 19549685 27898060 stimulant N/A OmniPath

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