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GENE：LETM2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LETM2
FullNmae leucine zipper and EF-hand containing transmembrane protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14648
EnsembleID ENSG00000165046
Uniprot Q2VYF4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LETM2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LETM2 GO:0005743,GO:0043022

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LETM2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LETM2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 LETM2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 LETM2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 LETM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LETM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LETM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LETM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LETM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LETM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LETM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004CCA62 LETM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 LETM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA LETM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF LETM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 LETM2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B LETM2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 LETM2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 LETM2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GABARAPL1 LETM2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
APP LETM2 25348397 N/A physical interaction ComPPI

Visualization










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