GENE：RAB3GAP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RAB3GAP1 |
| FullNmae | RAB3 GTPase activating protein catalytic subunit 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17063 |
| EnsembleID | ENSG00000115839 |
| Uniprot | Q15042 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RAB3GAP1 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| RAB3GAP1 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RAB3GAP1 | GO:0005085,GO:0005085,GO:0005096,GO:0005096,GO:0005096,GO:0005515,GO:0005789,GO:0005794,GO:0005811,GO:0005829,GO:0007420,GO:0021854,GO:0031267,GO:0032991,GO:0034389,GO:0043010,GO:0043087,GO:0043547,GO:0043547,GO:0043547,GO:0048172,GO:0060079,GO:0060325,GO:0061646,GO:0070062,GO:0071782,GO:0097051,GO:0098794,GO:1903061,GO:1903233,GO:1903373,GO:2000786 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | RAB3GAP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | RAB3GAP1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | RAB3GAP1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | RAB3GAP1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | RAB3GAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RAB3GAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | RAB3GAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RAB3GAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RAB3GAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | RAB3GAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | RAB3GAP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | RAB3GAP1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000032BDF4 | RAB3GAP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000096022 | RAB3GAP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BA274 | RAB3GAP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E008F | RAB3GAP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | RAB3GAP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | RAB3GAP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | RAB3GAP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | RAB3GAP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000202460 | RAB3GAP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | RAB3GAP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VCP | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| RPH3AL | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| FEZ1 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| VAPA | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| PAXIP1 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| CANX | RAB3GAP1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| NPHP1 | RAB3GAP1 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| FEZ2 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| RXRB | RAB3GAP1 | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| VAPB | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| PSMC4 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| ALOX5 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| MAP1LC3A | RAB3GAP1 | 20562859 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SIRT2 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| BRAF | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB22A | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB3GAP1 | PTP4A3 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| AP2B1 | RAB3GAP1 | 24234451 30021884 | physical association | cross-linking study | IntAct |