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GENE：CNN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CNN1
FullNmae calponin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2155
EnsembleID ENSG00000130176
Uniprot P51911

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CNN1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNN1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNN1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNN1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CNN1 GO:0005515,GO:0005516,GO:0005856,GO:0005925,GO:0006940,GO:0007015,GO:0015629,GO:0031032,GO:0051015,GO:1904706

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 CNN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC CNN1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA CNN1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TUBB CNN1 25348397 N/A physical interaction ComPPI
CALM1 CNN1 25348397 N/A physical interaction ComPPI
PRKCE CNN1 14525934 25348397 9312127 N/A experimental interaction detection,in vivo ComPPI,HPRD
CNN1 TPM3 14525934 2161834 2455687 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CNN1 ACTA1 12033495 14525934 2161834 2455687 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
CNN1 FYN 14525934 15206927 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CNN1 TPM1 25348397 N/A physical interaction ComPPI
CNN1 TNNC1 25348397 N/A physical interaction ComPPI
CNN1 DNMBP 25348397 N/A physical interaction ComPPI
CNN1 ADRB2 25348397 N/A physical interaction ComPPI
CNN1 MTHFD1 25348397 N/A physical interaction ComPPI
CNN1 MTHFD1L 25348397 N/A physical interaction ComPPI
CNN1 ESR2 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
CNN1 MYBPC3 21569246 24234451 25348397 physical association two hybrid ComPPI,IntAct
CNN1 SYCE1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
CNN1 CALM2 14525934 2161834 2455687 N/A experimental interaction detection HPRD
FYN CNN1 15206927 27898060 N/A N/A OmniPath

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