Gene Information gene info

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GENE：ACAT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACAT2
FullNmae acetyl-CoA acetyltransferase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:94
EnsembleID ENSG00000120437
Uniprot Q9BWD1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACAT2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ACAT2 GO:0003985,GO:0003985,GO:0005515,GO:0005737,GO:0005739,GO:0005829,GO:0006629,GO:0006635,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACAT2 hsa:39 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
ACAT2 hsa:39 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
ACAT2 hsa:39 path:hsa00310 Lysine degradation - Homo sapiens (human)
ACAT2 hsa:39 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
ACAT2 hsa:39 path:hsa00620 Pyruvate metabolism - Homo sapiens (human)
ACAT2 hsa:39 path:hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)
ACAT2 hsa:39 path:hsa00650 Butanoate metabolism - Homo sapiens (human)
ACAT2 hsa:39 path:hsa00900 Terpenoid backbone biosynthesis - Homo sapiens (human)
ACAT2 hsa:39 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ACAT2 hsa:39 path:hsa01200 Carbon metabolism - Homo sapiens (human)
ACAT2 hsa:39 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)
ACAT2 hsa:39 path:hsa04975 Fat digestion and absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LNX1 ACAT2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR ACAT2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ACAT2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 ACAT2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ACAT2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ACAT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ACAT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ACAT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ACAT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ACAT2 18971253 19478207 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ACAT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CDX2 ACAT2 16274362 trascriptional regulation,stimulation inferred by curator TFlink
HNF1A ACAT2 16274362 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
ACAT2 CDX1 25361965 interaction type N/A PTMCode2
CDX1 ACAT2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF1B ACAT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VASP ACAT2 25348397 N/A physical interaction ComPPI
BAG3 ACAT2 25348397 N/A physical interaction ComPPI
PCBP1 ACAT2 25348397 N/A physical interaction ComPPI
TRAF6 ACAT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KEAP1 ACAT2 25348397 N/A physical interaction ComPPI
PFDN4 ACAT2 25348397 N/A physical interaction ComPPI
UBE2L3 ACAT2 25348397 N/A physical interaction ComPPI
NTRK1 ACAT2 25348397 N/A physical interaction ComPPI
PIR ACAT2 25348397 N/A physical interaction ComPPI
CSNK2A1 ACAT2 14525934 16331323 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
VDAC1 ACAT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PABPC1 ACAT2 25348397 N/A physical interaction ComPPI
ZNF76 ACAT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PKM ACAT2 25348397 N/A physical interaction ComPPI
TNIK ACAT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCNA1 ACAT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SPR ACAT2 25348397 N/A physical interaction ComPPI
YWHAE ACAT2 25348397 N/A physical interaction ComPPI
CDX2 ACAT2 12518221 25348397 27898060 N/A in vivo ComPPI,OmniPath
ACAT2 TERF1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
ACAT2 SSU72 25348397 N/A physical interaction ComPPI
ACAT2 PSAT1 25348397 N/A physical interaction ComPPI
ACAT2 TTC39C 25348397 N/A physical interaction ComPPI
ACAT2 TKFC 25348397 N/A physical interaction ComPPI
ACAT2 ALDH9A1 25348397 N/A physical interaction ComPPI
ACAT2 FH 25348397 N/A physical interaction ComPPI
ACAT2 HEXA 25348397 N/A physical interaction ComPPI
ACAT2 OLA1 25348397 N/A physical interaction ComPPI
ACAT2 MC1R 25348397 N/A physical interaction ComPPI
ACAT2 TUBB3 25348397 N/A physical interaction ComPPI
ACAT2 UBA3 25348397 N/A physical interaction ComPPI
ACAT2 PAPSS1 25348397 N/A physical interaction ComPPI
ACAT2 LNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ACAT2 MOV10 25348397 N/A physical interaction ComPPI
ACAT2 MLST8 25348397 N/A physical interaction ComPPI
ACAT2 ACAT1 25348397 N/A physical interaction ComPPI
ACAT2 TRAPPC8 25348397 N/A physical interaction ComPPI
ACAT2 PPP4R3A 25348397 N/A physical interaction ComPPI
ACAT2 HADH 25348397 N/A physical interaction ComPPI
ACAT2 HSPE1 25348397 N/A physical interaction ComPPI
ACAT2 PCBP2 25348397 N/A physical interaction ComPPI
ACAT2 PRRC1 25348397 N/A physical interaction ComPPI
ACAT2 UBXN1 25348397 N/A physical interaction ComPPI
ACAT2 AKT1 25348397 N/A physical interaction ComPPI
ACAT2 MED20 25348397 N/A physical interaction ComPPI
ACAT2 ATG5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACAT2 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACAT2 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACAT2 GNAS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACAT2 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACAT2 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACAT2 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
AHCY ACAT2 25348397 N/A physical interaction ComPPI
HMGB3 ACAT2 25348397 N/A physical interaction ComPPI
ACAT2 ACAT2 14525934 15733928 21988832 24234451 25416956 physical association two hybrid,experimental interaction detection,two hybrid array HPRD,IntAct

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