GENE:VMP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | VMP1 |
| FullNmae | vacuole membrane protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29559 |
| EnsembleID | ENSG00000062716 |
| Uniprot | Q96GC9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| VMP1 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| VMP1 | GO:0000045,GO:0000045,GO:0000407,GO:0000421,GO:0005515,GO:0005730,GO:0005783,GO:0005783,GO:0005789,GO:0005886,GO:0006914,GO:0006914,GO:0007030,GO:0007566,GO:0012505,GO:0016020,GO:0016240,GO:0017121,GO:0017128,GO:0033116,GO:0034329,GO:0042953,GO:0098609,GO:0140056,GO:1901896,GO:1990456 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| VMP1 | hsa:81671 | path:hsa04140 | Autophagy - animal - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | VMP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | VMP1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | VMP1 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | VMP1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | VMP1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | VMP1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | VMP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GLI3 | VMP1 | 22535956 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F2 | VMP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000055128B | VMP1 | 22144109 | rna interference,inhibition | array technology,western blot,miRNA interference luciferase reporter assay | miRSponge |
| URS000055128B | VMP1 | 22144109 24632577 25416803 | mrna cleavage,inhibition | array technology,western blot,miRNA interference luciferase reporter assay | TarBase |
| URS00001C3AC1 | VMP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000C85B2 | VMP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000EC1BE | VMP1 | 20371350 21572407 22927820 23313552 23592263 23706177 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00003003B4 | VMP1 | 20371350 21572407 22927820 23313552 23592263 23706177 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00001481F9 | VMP1 | 20371350 21572407 22927820 23313552 23592263 23706177 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDAA | VMP1 | 20371350 21572407 22927820 23313552 23592263 23706177 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000023133F | VMP1 | 19536157 20371350 21572407 22927820 23313552 23446348 23592263 23706177 23824327 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000284586 | VMP1 | 21572407 22927820 23313552 23592263 23706177 24906430 25416803 26701625 27292025 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000017EA6A | VMP1 | 19536157 20371350 21572407 22927820 23313552 23446348 23592263 23706177 23824327 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00004505E4 | VMP1 | 19536157 20371350 21572407 22927820 23313552 23446348 23592263 23706177 23824327 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D5659 | VMP1 | 19536157 20371350 21572407 22927820 23313552 23446348 23592263 23706177 23824327 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000031BC7D | VMP1 | 19536157 23313552 23446348 23592263 23824327 25416803 26701625 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000028BB8 | VMP1 | 19536157 20371350 21572407 22927820 23313552 23446348 23592263 23706177 23824327 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00001AFC71 | VMP1 | 19536157 20371350 21572407 22927820 23313552 23446348 23592263 23706177 23824327 24906430 25416803 26701625 27292025 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000040780F | VMP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | VMP1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A611 | VMP1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | VMP1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMNA | VMP1 | 25348397 | N/A | physical interaction | ComPPI |
| DPEP1 | VMP1 | 25348397 | N/A | physical interaction | ComPPI |
| HGS | VMP1 | 25348397 | N/A | physical interaction | ComPPI |
| BECN1 | VMP1 | 23316280 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation | ComPPI,IntAct |
| PIK3C3 | VMP1 | 23316280 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| ELAVL1 | VMP1 | 25348397 | N/A | physical interaction | ComPPI |
| CDH13 | VMP1 | 25348397 | N/A | physical interaction | ComPPI |
| FAF2 | VMP1 | 25348397 | N/A | physical interaction | ComPPI |
| CYB5R3 | VMP1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TMEM216 | VMP1 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| MAS1 | VMP1 | 25348397 | N/A | physical interaction | ComPPI |
| TJP1 | VMP1 | 17724469 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy | ComPPI,IntAct,OmniPath |
| ERGIC3 | VMP1 | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VMP1 | KLK11 | 25348397 | N/A | physical interaction | ComPPI |
| VMP1 | LPAR6 | 25348397 | N/A | physical interaction | ComPPI |
| VMP1 | TCTN2 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| VMP1 | TCTN3 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| VMP1 | SLC39A9 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| VMP1 | FAM209A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| HSCB | VMP1 | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| VMP1 | BECN1 | 17940279 19056683 23316280 27898060 | stimulant | N/A | OmniPath |
