GENE:LCOR
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | LCOR |
| FullNmae | ligand dependent nuclear receptor corepressor |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29503 |
| EnsembleID | ENSG00000196233 |
| Uniprot | Q96JN0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| LCOR | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| LCOR | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| LCOR | GO:0000122,GO:0001222,GO:0003677,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0006357,GO:0030331,GO:0042826,GO:0071392,GO:1990226,GO:1990381 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| LCOR | hsa:84458 | path:hsa03083 | Polycomb repressive complex - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | LCOR | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | LCOR | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | LCOR | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | LCOR | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | LCOR | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | LCOR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003D5391 | LCOR | 21565892 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
| URS00003D5391 | LCOR | 21565892 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS000048BA36 | LCOR | 20371350 21572407 25416803 27292025 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
| URS0000237AF9 | LCOR | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000070B1D | LCOR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000AA464 | LCOR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000330617 | LCOR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002075FA | LCOR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000250A40 | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031D186 | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | LCOR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B59A2 | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052E1A6 | LCOR | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | LCOR | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC864 | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000183BED | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDCD1 | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004977C5 | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065D58 | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CF5F | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E92A8 | LCOR | 20371350 21572407 22012620 23446348 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DE669 | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000324096 | LCOR | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F8148 | LCOR | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122ED0 | LCOR | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023BE29 | LCOR | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FFA8C | LCOR | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039607D | LCOR | 20371350 21572407 22012620 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C04A2 | LCOR | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C28B2 | LCOR | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016E46F | LCOR | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040780F | LCOR | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB14 | LCOR | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E177F | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | LCOR | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | LCOR | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000014F13C | LCOR | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000279B6F | LCOR | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000015A0D9 | LCOR | 21572407 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000016914 | LCOR | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000033EBB8 | LCOR | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | LCOR | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | LCOR | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | LCOR | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | LCOR | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | LCOR | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005BB0FD | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000035AC91 | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | LCOR | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000913AC | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027464B | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002D2333 | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001481F9 | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B59DF | LCOR | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004BC299 | LCOR | 21572407 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | LCOR | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000136174 | LCOR | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CC709 | LCOR | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000358C16 | LCOR | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | LCOR | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CEB74 | LCOR | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F0130 | LCOR | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CE046 | LCOR | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170D8B | LCOR | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000015188E | LCOR | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CE0C6 | LCOR | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004C5774 | LCOR | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045147B | LCOR | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000022B729 | LCOR | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018CD09 | LCOR | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000284586 | LCOR | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005C1F22 | LCOR | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000034979B | LCOR | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000254A6 | LCOR | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | LCOR | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | LCOR | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GOLGA2 | LCOR | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| CBX8 | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| KPNA3 | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| KPNA4 | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RPF1 | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SLC25A6 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| CRK | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| EHMT2 | LCOR | 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| EZH2 | LCOR | 24234451 25348397 26496610 27705803 | association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
| AR | LCOR | 21856747 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| VDR | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| USP7 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| HDAC3 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| MAPK14 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| CTBP1 | LCOR | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| CTBP2 | LCOR | 24234451 25348397 25416956 27705803 | association,physical association | physical interaction,two hybrid array,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| HDAC4 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| GRN | LCOR | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| KPNB1 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| DEK | LCOR | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LRP1 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| NDE1 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | LCOR | 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| RBBP4 | LCOR | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| TRAF1 | LCOR | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| OBSCN | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| H1-4 | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CCT5 | LCOR | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| KLF6 | LCOR | 22277651 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| POGZ | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| HDAC6 | LCOR | 12535528 19744931 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| EED | LCOR | 24234451 25348397 26496610 27705803 | association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
| H3C1 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| TFEB | LCOR | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BAZ2A | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| ESR1 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| CDYL | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| EZH1 | LCOR | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| RFC1 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| CNOT2 | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| RAB4B | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| SUZ12 | LCOR | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| RBPJ | LCOR | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | DECR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCOR | RPL30 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCOR | PRRC2C | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | NBEAL2 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | NIPSNAP1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCOR | NOP9 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCOR | WDR76 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCOR | SAMHD1 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | MIA | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | USP43 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | LRWD1 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | SRFBP1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| LCOR | ZNF516 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | ASB3 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | ZYG11B | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | LRPAP1 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | KLHDC3 | 25348397 | N/A | physical interaction | ComPPI |
| LCOR | MTF2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | CCT6A | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | PHF1 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | CCT2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | RPL39 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | CCT4 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | PHF19 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | RBBP7 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LCOR | TUBA1C | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| HNRNPDL | LCOR | 24234451 30021884 | physical association | cross-linking study | IntAct |
