Gene Information gene info

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GENE：LAMB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LAMB1
FullNmae laminin subunit beta 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6486
EnsembleID ENSG00000091136
Uniprot P07942

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LAMB1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LAMB1 GO:0005198,GO:0005201,GO:0005201,GO:0005201,GO:0005515,GO:0005576,GO:0005604,GO:0005604,GO:0005604,GO:0005606,GO:0005606,GO:0005606,GO:0005607,GO:0005607,GO:0005615,GO:0005788,GO:0007155,GO:0021812,GO:0030335,GO:0031175,GO:0034446,GO:0035987,GO:0042476,GO:0043257,GO:0043257,GO:0043259,GO:0045785,GO:0048471,GO:0050679,GO:0051149,GO:0062023,GO:0062023,GO:0070062,GO:0098637,GO:0110011,GO:2001046

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LAMB1 hsa:3912 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
LAMB1 hsa:3912 path:hsa04510 Focal adhesion - Homo sapiens (human)
LAMB1 hsa:3912 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)
LAMB1 hsa:3912 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
LAMB1 hsa:3912 path:hsa05146 Amoebiasis - Homo sapiens (human)
LAMB1 hsa:3912 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
LAMB1 hsa:3912 path:hsa05200 Pathways in cancer - Homo sapiens (human)
LAMB1 hsa:3912 path:hsa05222 Small cell lung cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ERBIN LAMB1 15123239 23180781 physical association peptide array InnateDB
CACNA1A LAMB1 21078624 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR LAMB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 LAMB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 LAMB1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 LAMB1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 LAMB1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA LAMB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LAMB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LAMB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LAMB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LAMB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LAMB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 LAMB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NANOG LAMB1 15983365 trascriptional regulation,stimulation inferred by curator TFlink
SSB LAMB1 21896617 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A LAMB1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LAMB1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000512C88 LAMB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039A052 LAMB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 LAMB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F0C23 LAMB1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
LAMB1 LAMA5 25361965 interaction type N/A PTMCode2
LAMA5 LAMB1 25361965 interaction type N/A PTMCode2
LAMB1 ACHE 25361965 interaction type N/A PTMCode2
ACHE LAMB1 25361965 interaction type N/A PTMCode2
LAMB1 LAMA3 25361965 interaction type N/A PTMCode2
LAMA3 LAMB1 25361965 interaction type N/A PTMCode2
LAMB1 LAMC3 25361965 interaction type N/A PTMCode2
LAMC3 LAMB1 25361965 interaction type N/A PTMCode2
LAMB1 COL6A1 25361965 interaction type N/A PTMCode2
COL6A1 LAMB1 25361965 interaction type N/A PTMCode2
LAMB1 LAMA1 25361965 interaction type N/A PTMCode2
LAMA1 LAMB1 25361965 interaction type N/A PTMCode2
LAMB1 LAMA2 25361965 interaction type N/A PTMCode2
LAMA2 LAMB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LGALS3 LAMB1 25348397 N/A physical interaction ComPPI
DPY30 LAMB1 25348397 N/A physical interaction ComPPI
CEP43 LAMB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFB1 LAMB1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LMNA LAMB1 25348397 N/A physical interaction ComPPI
ERBIN LAMB1 25348397 N/A physical interaction ComPPI
PDIA3 LAMB1 17170699 24234451 25348397 disulfide bond anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC LAMB1 25348397 N/A physical interaction ComPPI
NTRK1 LAMB1 25348397 N/A physical interaction ComPPI
PA2G4 LAMB1 25348397 N/A physical interaction ComPPI
ACHE LAMB1 14525934 15474030 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PSMC5 LAMB1 25348397 N/A physical interaction ComPPI
GFI1B LAMB1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CACNA1A LAMB1 21078624 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
POLR2E LAMB1 25348397 N/A physical interaction ComPPI
LAMB1 ATXN7L2 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
LAMB1 COL6A1 10407855 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
LAMB1 ATXN7 21078624 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
LAMB1 LAMC1 25348397 N/A physical interaction ComPPI
LAMB1 FBXO6 25348397 N/A physical interaction ComPPI
LAMB1 NQO1 25348397 N/A physical interaction ComPPI
LAMB1 HSPD1 25348397 N/A physical interaction ComPPI
LAMB1 HECW2 25348397 N/A physical interaction ComPPI
LAMB1 WASHC4 25348397 N/A physical interaction ComPPI
LAMB1 ANTXR2 25348397 N/A physical interaction ComPPI
LAMB1 NTF3 25348397 N/A physical interaction ComPPI
LAMB1 OGN 25348397 N/A physical interaction ComPPI
LAMB1 LGALS9 25348397 N/A physical interaction ComPPI
LAMB1 TMEM25 25348397 N/A physical interaction ComPPI
LAMB1 PTPRK 25348397 N/A physical interaction ComPPI
LAMB1 CD96 25348397 N/A physical interaction ComPPI
LAMB1 PSMD5 25348397 N/A physical interaction ComPPI
LAMB1 KIF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LAMB1 SERPINA12 25348397 N/A physical interaction ComPPI
LAMB1 OS9 25348397 N/A physical interaction ComPPI
LAMB1 DEFA1 25348397 N/A physical interaction ComPPI
LAMB1 COLEC12 25348397 N/A physical interaction ComPPI
LAMB1 CRP 25348397 N/A physical interaction ComPPI
LAMB1 LYZL2 25348397 N/A physical interaction ComPPI
LAMB1 PSG8 25348397 N/A physical interaction ComPPI
LAMB1 ESR2 21182203 24234451 25348397 association cosedimentation through density gradient ComPPI,IntAct
LAMB1 KARS1 24234451 24983501 25348397 N/A nuclear magnetic resonance ComPPI,IntAct
LAMB1 PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
LAMB1 SEPTIN12 24234451 25348397 25775403 colocalization fluorescence microscopy ComPPI,IntAct
LAMB1 CD79A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAMB1 GPR152 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LAMB1 UBQLN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCAM LAMB1 25348397 N/A physical interaction ComPPI
DAG1 LAMB1 24234451 association cross-linking study IntAct
L1TD1 LAMB1 24234451 25702638 association anti bait coimmunoprecipitation IntAct
LAMB1 ITGB4 10842354 27898060 stimulant N/A OmniPath
CACNA1A LAMB1 21078624 27898060 N/A N/A OmniPath
ERBIN LAMB1 15123239 27898060 N/A N/A OmniPath
LAMB1 ITGA6 10842354 27898060 stimulant N/A OmniPath
LAMB1 ITGB8 27898060 7542940 stimulant N/A OmniPath
LAMB1 CD151 10842354 15677332 27898060 stimulant N/A OmniPath

Visualization










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