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GENE：LARP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LARP1
FullNmae La ribonucleoprotein 1, translational regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29531
EnsembleID ENSG00000155506
Uniprot Q6PKG0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LARP1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LARP1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LARP1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
LARP1 GO:0000339,GO:0000340,GO:0003723,GO:0003723,GO:0003730,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0006413,GO:0008190,GO:0008283,GO:0008494,GO:0010494,GO:0010494,GO:0010608,GO:0016020,GO:0016239,GO:0017148,GO:0031369,GO:0031929,GO:0038202,GO:0042788,GO:0043024,GO:0045070,GO:0045296,GO:0045727,GO:0045947,GO:0045948,GO:0048027,GO:0048027,GO:0048255,GO:0072752,GO:1990928

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EZH2 LARP1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 LARP1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 LARP1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SRPK1 LARP1 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 LARP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 LARP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 LARP1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 LARP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 LARP1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 LARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 LARP1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D LARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE LARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 LARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE LARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB LARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA LARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 LARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000285DCB LARP1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B LARP1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 LARP1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F LARP1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 LARP1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 LARP1 20371350 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 LARP1 20371350 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB LARP1 20371350 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 LARP1 20371350 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 LARP1 20371350 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 LARP1 20371350 21572407 22012620 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 LARP1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE LARP1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 LARP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 LARP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 LARP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B LARP1 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000E7139 LARP1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 LARP1 25416803 26063484 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00002971AB LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004CCDA3 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000048F59D LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000FC8EB LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000821E0 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000055128B LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002D0FC3 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000FFC8B LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002A79D1 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000116F83 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002AB575 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D1FC LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A9CF LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BE495 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F9738 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000020579D LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000004BACE LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001919B0 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000585553 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000058BB84 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005E1A16 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000036AFF1 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001A7F58 LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA LARP1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 LARP1 22135298 phosphorylation N/A PhosphoSite
MTOR LARP1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
DDX6 LARP1 23986595 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CUL5 LARP1 25348397 N/A physical interaction ComPPI
EIF1B LARP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NPM1 LARP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GABARAPL2 LARP1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NOL12 LARP1 25348397 N/A physical interaction ComPPI
YWHAG LARP1 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
SNIP1 LARP1 25348397 N/A physical interaction ComPPI
NIFK LARP1 25348397 N/A physical interaction ComPPI
EIF3E LARP1 25348397 N/A physical interaction ComPPI
KASH5 LARP1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LARP1 YWHAB 15324660 17353931 24234451 24255178 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
LARP1 YWHAZ 15161933 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,pull down,physical interaction,in vivo ComPPI,IntAct
LARP1 RRP1B 25348397 N/A physical interaction,tandem affinity purification ComPPI
LARP1 TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LARP1 ELAVL1 25348397 N/A physical interaction ComPPI
LARP1 SIRT7 25348397 N/A physical interaction ComPPI
LARP1 TSG101 25348397 N/A physical interaction ComPPI
LARP1 NFX1 25348397 N/A physical interaction ComPPI
LARP1 CUL3 25348397 N/A physical interaction ComPPI
LARP1 CUL4B 25348397 N/A physical interaction ComPPI
LARP1 CUL2 25348397 N/A physical interaction ComPPI
LARP1 CUL1 25348397 N/A physical interaction ComPPI
LARP1 COPS5 25348397 N/A physical interaction ComPPI
LARP1 CAND1 25348397 N/A physical interaction ComPPI
LARP1 GRK5 25348397 N/A physical interaction ComPPI
LARP1 MRPL12 25348397 N/A physical interaction ComPPI
LARP1 SLC25A10 25348397 N/A physical interaction ComPPI
LARP1 CDCA5 25348397 N/A physical interaction ComPPI
LARP1 BARD1 25348397 N/A physical interaction ComPPI
LARP1 ECT2 25348397 N/A physical interaction ComPPI
LARP1 PAXIP1 25348397 N/A physical interaction ComPPI
LARP1 CSNK2A1 25348397 N/A physical interaction,protein kinase assay ComPPI
LARP1 YWHAE 25348397 N/A physical interaction ComPPI
LARP1 ITGA4 25348397 N/A physical interaction ComPPI
LARP1 CLK3 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LARP1 SRPK1 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
LARP1 TARDBP 25348397 N/A physical interaction ComPPI
LARP1 EIF3A 25348397 N/A physical interaction ComPPI
LARP1 EIF3C 25348397 N/A physical interaction ComPPI
LARP1 EIF3L 25348397 N/A physical interaction ComPPI
LARP1 EIF3K 25348397 N/A physical interaction ComPPI
LARP1 RPS10 25348397 N/A physical interaction ComPPI
LARP1 RPS12 25348397 N/A physical interaction ComPPI
LARP1 RPS13 25348397 N/A physical interaction ComPPI
LARP1 RPS14 25348397 N/A physical interaction ComPPI
LARP1 RPS16 25348397 N/A physical interaction ComPPI
LARP1 RPS18 25348397 N/A physical interaction ComPPI
LARP1 RPS29 25348397 N/A physical interaction ComPPI
LARP1 RPS3 25348397 N/A physical interaction ComPPI
LARP1 RPS3A 25348397 N/A physical interaction ComPPI
LARP1 RPS4X 25348397 N/A physical interaction ComPPI
LARP1 RPS5 25348397 N/A physical interaction ComPPI
LARP1 RPS8 25348397 N/A physical interaction ComPPI
LARP1 RPS9 25348397 N/A physical interaction ComPPI
LARP1 LIN28A 25348397 N/A physical interaction ComPPI
LARP1 IVNS1ABP 25348397 N/A physical interaction ComPPI
LARP1 AURKA 25348397 N/A physical interaction ComPPI
LARP1 EZH2 25348397 N/A physical interaction ComPPI
LARP1 SUZ12 25348397 N/A physical interaction ComPPI
LARP1 RNF2 25348397 N/A physical interaction ComPPI
LARP1 H1-1 25348397 N/A physical interaction ComPPI
LARP1 SURF2 25348397 N/A physical interaction ComPPI
LARP1 TRA2A 25348397 N/A physical interaction ComPPI
LARP1 RPL6 25348397 N/A physical interaction ComPPI
LARP1 HNRNPDL 25348397 N/A physical interaction ComPPI
LARP1 ZC3H3 25348397 N/A physical interaction ComPPI
LARP1 HNRNPA1 25348397 N/A physical interaction ComPPI
LARP1 PRR11 25348397 N/A physical interaction ComPPI
LARP1 LUC7L 25348397 N/A physical interaction ComPPI
LARP1 LUC7L2 25348397 N/A physical interaction ComPPI
LARP1 NLRP2 25348397 N/A physical interaction ComPPI
LARP1 NTRK1 25348397 N/A physical interaction ComPPI
LARP1 IFI16 25348397 N/A physical interaction ComPPI
LARP1 HNRNPU 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LARP1 CNOT2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LARP1 RPL10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LARP1 NOP56 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LARP1 FOXG1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LARP1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LARP1 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LARP1 U2AF2 25348397 N/A physical interaction ComPPI
LARP1 RC3H1 25348397 N/A physical interaction ComPPI
LARP1 CDH1 25348397 N/A physical interaction ComPPI
LARP1 LARP1B 25348397 N/A physical interaction ComPPI
LARP1 GSPT2 25348397 N/A physical interaction ComPPI
LARP1 SNRNP70 25348397 N/A physical interaction ComPPI
LARP1 ZC3HAV1 25348397 N/A physical interaction ComPPI
LARP1 ZCRB1 25348397 N/A physical interaction ComPPI
LARP1 SART3 25348397 N/A physical interaction ComPPI
LARP1 H1-4 25348397 N/A physical interaction ComPPI
LARP1 PPAN 25348397 N/A physical interaction ComPPI
LARP1 DGCR8 25348397 N/A physical interaction ComPPI
LARP1 ELAVL2 25348397 N/A physical interaction ComPPI
LARP1 STRBP 25348397 N/A physical interaction ComPPI
LARP1 FGF8 25348397 N/A physical interaction ComPPI
LARP1 ZFC3H1 25348397 N/A physical interaction ComPPI
LARP1 BHLHA15 25348397 N/A physical interaction ComPPI
LARP1 KCTD3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 KIF13B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 ZBTB21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 GIGYF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 LRFN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 DENND1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 SH3PXD2A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 SRGAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 EIF4E2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 SIPA1L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 CGN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 RTKN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 MAST3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 LIMA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 TESK2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 PPM1H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 DCLK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 ZNF638 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LARP1 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
LARP1 TRIM25 25348397 N/A physical interaction ComPPI
LARP1 G3BP1 25348397 N/A physical interaction ComPPI
LARP1 BRCA1 25348397 N/A physical interaction ComPPI
LARP1 HNRNPL 25348397 N/A physical interaction ComPPI
LARP1 YWHAH 17979178 24234451 25348397 association tandem affinity purification ComPPI,IntAct
LARP1 ESR1 21182205 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
LARP1 ESR2 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
LARP1 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LARP1 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
LARP1 YBX1 23986595 24234451 25348397 25497084 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
LARP1 DHX9 23986595 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LARP1 ILF3 23986595 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LARP1 PABPN1 23986595 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LARP1 IGF2BP2 23986595 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LARP1 DDX3X 23986595 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LARP1 L1RE1 24234451 24267889 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LARP1 CD247 24234451 24502978 25348397 association pull down ComPPI,IntAct
LARP1 MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
LARP1 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
LARP1 PLEKHA7 25348397 N/A anti bait coimmunoprecipitation ComPPI
LARP1 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
LARP1 FBL 24234451 25348397 29568061 association pull down ComPPI,IntAct
LARP1 HIF1AN 25348397 N/A anti tag coimmunoprecipitation ComPPI
BCL2L1 LARP1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CBY1 LARP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YWHAQ LARP1 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
SOX2 LARP1 25348397 N/A physical interaction ComPPI
H3C1 LARP1 24234451 25348397 29568061 association pull down ComPPI,IntAct
ILF2 LARP1 23986595 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct

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