Gene Information gene info

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GENE：TRIM8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TRIM8
FullNmae tripartite motif containing 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15579
EnsembleID ENSG00000171206
Uniprot Q9BZR9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TRIM8 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TRIM8 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TRIM8 GO:0003713,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0007249,GO:0008270,GO:0010508,GO:0016567,GO:0016605,GO:0019827,GO:0031435,GO:0032897,GO:0042802,GO:0042803,GO:0043123,GO:0044790,GO:0045087,GO:0045893,GO:0046597,GO:0051091,GO:0051092,GO:0061630,GO:1900182

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRIM8 PIAS3 20516148 ubiquitination reaction,inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 TRIM8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 TRIM8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TRIM8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 TRIM8 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 TRIM8 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00002075FA TRIM8 22473208 23622248 25416803 26077989 28327152 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,clash,miRNA interference luciferase reporter assay TarBase
URS0000042E1F TRIM8 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 TRIM8 22473208 25416803 28327152 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002B3783 TRIM8 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 TRIM8 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001D69F6 TRIM8 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 TRIM8 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E TRIM8 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 TRIM8 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 TRIM8 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB TRIM8 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC379 TRIM8 25416803 28280352 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CCNH TRIM8 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRIM21 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HOXA1 TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CATSPER1 TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBASH3A TRIM8 25348397 N/A two hybrid ComPPI
TNFAIP3 TRIM8 25348397 N/A physical interaction ComPPI
MAGEA1 TRIM8 25348397 N/A physical interaction ComPPI
XIAP TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MKRN3 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D1 TRIM8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DCUN1D1 TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSP90AB1 TRIM8 21689689 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBE2D4 TRIM8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAGEC2 TRIM8 25348397 N/A physical interaction ComPPI
RNF7 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CBL TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SOCS1 TRIM8 12163497 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RNF111 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
USP7 TRIM8 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D2 TRIM8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SIAH1 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HGS TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNS2 TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UHRF2 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAD18 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM24 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAD23A TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF168 TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ITSN1 TRIM8 25348397 N/A physical interaction ComPPI
TRAF5 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RCHY1 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAP3K7 TRIM8 25348397 N/A physical interaction ComPPI
UBE2D3 TRIM8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM25 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2L6 TRIM8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF41 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ELAVL1 TRIM8 25348397 N/A physical interaction ComPPI
PIAS3 TRIM8 25348397 N/A physical interaction ComPPI
TRIM27 TRIM8 22829933 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2V1 TRIM8 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NOD2 TRIM8 22829933 24234451 25348397 physical association two hybrid ComPPI,IntAct
TRIM8 UBE2W 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 USP2 25348397 N/A physical interaction ComPPI
TRIM8 USP21 25348397 N/A physical interaction ComPPI
TRIM8 USP39 25348397 N/A physical interaction ComPPI
TRIM8 OTUB2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM8 TP53 25348397 N/A physical interaction ComPPI
TRIM8 RC3H2 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 RNF113A 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 TRIM47 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 MSL2 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 TRIM15 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 RNF138 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 BRAP 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 TRIM2 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 RNF181 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 RNF141 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 PCGF5 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 TRIM9 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 TRIM39 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 KLHL2 25348397 N/A physical interaction ComPPI
TRIM8 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM8 LONRF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM8 TNIP3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM8 YOD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM8 UBXN7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM8 MTURN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDT10 TRIM8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM43 TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM8 TRIM8 11331580 14525934 22493164 22829933 24234451 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,two hybrid array,two hybrid HPRD,IntAct
TRIM8 SOCS1 12163497 27898060 inhibition N/A OmniPath

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