GENE:MAPKAPK2
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | MAPKAPK2 |
FullNmae | MAPK activated protein kinase 2 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:6887 |
EnsembleID | ENSG00000162889 |
Uniprot | P49137 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
MAPKAPK2 | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MAPKAPK2 | necroptosis | 40508046 | The aim of this study was to analyse the occurrence of polymorphisms in genes encoding key proteins for the necroptosis process, i.e., RIPK-1, RIPK-3 and MAPKAPK2. | retulator signature |
MAPKAPK2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MAPKAPK2 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
MAPKAPK2 | GO:0000165,GO:0002224,GO:0002224,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004683,GO:0005515,GO:0005516,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005813,GO:0005829,GO:0006468,GO:0006691,GO:0006954,GO:0006954,GO:0006974,GO:0009931,GO:0010803,GO:0018105,GO:0018105,GO:0032496,GO:0032675,GO:0032680,GO:0032760,GO:0034097,GO:0034097,GO:0035556,GO:0035924,GO:0035924,GO:0038066,GO:0043488,GO:0044351,GO:0046777,GO:0048010,GO:0048010,GO:0048010,GO:0048839,GO:0051019,GO:0060907,GO:0070062,GO:0070935,GO:0106310,GO:1900034 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
MAPKAPK2 | hsa:9261 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
MAPKAPK2 | hsa:9261 | path:hsa04148 | Efferocytosis - Homo sapiens (human) |
MAPKAPK2 | hsa:9261 | path:hsa04218 | Cellular senescence - Homo sapiens (human) |
MAPKAPK2 | hsa:9261 | path:hsa04370 | VEGF signaling pathway - Homo sapiens (human) |
MAPKAPK2 | hsa:9261 | path:hsa04625 | C-type lectin receptor signaling pathway - Homo sapiens (human) |
MAPKAPK2 | hsa:9261 | path:hsa04722 | Neurotrophin signaling pathway - Homo sapiens (human) |
MAPKAPK2 | hsa:9261 | path:hsa05167 | Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human) |
MAPKAPK2 | hsa:9261 | path:hsa05203 | Viral carcinogenesis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
MAPK14 | MAPKAPK2 | 10581204 11042204 11551945 17255097 18988627 21071413 23180781 23331499 7592979 8846784 9768359 9922370 | phosphorylation reaction,stimulation,physical association | gst pull down,x-ray crystallography,in-gel kinase assay,protein kinase assay | InnateDB,SignaLink,SignaLink |
AKT2 | MAPKAPK2 | 16793766 23180781 | phosphorylation reaction | in-gel kinase assay | InnateDB |
MAPKAPK2 | MAPKAPK2 | 12565831 17389598 20626350 23180781 26467481 8887554 | phosphorylation reaction,up-regulates,up-regulates activity | protein kinase assay | InnateDB,Signor |
PABPC1 | MAPKAPK2 | 12565831 23180781 | phosphorylation reaction | protein kinase assay | InnateDB |
MAPKAPK2 | ELAVL1 | 19322201 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
LSP1 | MAPKAPK2 | 20005715 | interaction type | N/A | PSP |
SHC1 | MAPKAPK2 | 20005715 | interaction type | N/A | PSP |
YWHAZ | MAPKAPK2 | 20005715 | interaction type | N/A | PSP |
YWHAZ | MAPKAPK2 | 20005715 20005715 | N/A | N/A | SignaLink |
SHC1 | MAPKAPK2 | 15094067 15094067 20005715 20005715 21071413 | N/A | N/A | SignaLink |
LSP1 | MAPKAPK2 | 20005715 20005715 | N/A | N/A | SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | MAPKAPK2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | MAPKAPK2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | MAPKAPK2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | MAPKAPK2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | MAPKAPK2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
PRDM14 | MAPKAPK2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | MAPKAPK2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00003D5391 | MAPKAPK2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000AA464 | MAPKAPK2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000005481D | MAPKAPK2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000171CD1 | MAPKAPK2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000041CB9C | MAPKAPK2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040EE1D | MAPKAPK2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000076B539 | MAPKAPK2 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS000003575B | MAPKAPK2 | 23313552 23824327 25416803 26701625 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS000009A9A2 | MAPKAPK2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000033B548 | MAPKAPK2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000045ED38 | MAPKAPK2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000027F5F3 | MAPKAPK2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00005F9738 | MAPKAPK2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001F373E | MAPKAPK2 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002AA55A | MAPKAPK2 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00000EBD4B | MAPKAPK2 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
MAPKAPK2 | CDC25B | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | HNRNPA0 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | HSPB1 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPKAPK2 | LIMK1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | WNK4 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | CREB1 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPKAPK2 | RCSD1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | MRTFA | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | YWHAZ | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | AGO2 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | BAG2 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | MDM2 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | EEF2K | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | KRT18 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | MAPKAPK2 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | ZFP36L1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | PLK1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | CEP131 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | AKT1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | ARPC5 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | TP53 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | TRIM29 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | PARN | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | DDX5 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | DAZL | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | SRF | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPKAPK2 | TRIM28 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | TH | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPKAPK2 | LSP1 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPKAPK2 | PIAS1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | ALOX5 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPKAPK2 | AATF | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | HSF1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | BCL2L1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | PFKFB3 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | TSC2 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | CDC25C | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | BECN1 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPKAPK2 | KRT20 | 22135298 | phosphorylation | N/A | PhosphoSite |
MAPK14 | MAPKAPK2 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPK1 | MAPKAPK2 | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
MAPKAPK2 | MAPK1 | 25361965 | interaction type | N/A | PTMCode2 |
HSPB1 | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
SRF | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
ALOX5 | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
TH | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
CREB1 | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
TCF3 | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
MAPKAPK2 | TCF3 | 25361965 | interaction type | N/A | PTMCode2 |
YWHAB | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
MAPKAPK2 | YWHAB | 25361965 | interaction type | N/A | PTMCode2 |
LSP1 | MAPKAPK2 | 25361965 | interaction type | N/A | PTMCode2 |
MAPKAPK2 | MAPK14 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PIAS2 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
DES | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
PHC2 | MAPKAPK2 | 14525934 15094067 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
BCL2L1 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
MAPK1 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
SHC1 | MAPKAPK2 | 14525934 15094067 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
ETV1 | MAPKAPK2 | 11551945 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
MAPK3 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
COPS5 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK5 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
MAPK14 | MAPKAPK2 | 14525934 17255097 21988832 23455922 23602568 24234451 25241761 25348397 25852190 26496610 7592979 8846784 9768359 | association,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,x-ray crystallography,physical interaction,in vitro,in vivo,tandem affinity purification,proximity ligation assay,two hybrid | ComPPI,HPRD,IntAct |
SRF | MAPKAPK2 | 10318869 10753652 12171911 14525934 25348397 8413226 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
CUL3 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
YWHAZ | MAPKAPK2 | 12861023 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
WASF1 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
PLK1 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
THAP12 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
ZFP36 | MAPKAPK2 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
DDX5 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
TRIM29 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
PABPC1 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
PKM | MAPKAPK2 | 25348397 | N/A | protein kinase assay | ComPPI |
TSC2 | MAPKAPK2 | 12582162 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
XPO1 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
AATF | MAPKAPK2 | 22909821 24234451 25348397 | phosphorylation reaction | protein kinase assay | ComPPI,IntAct |
SMNDC1 | MAPKAPK2 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
MDM2 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
ALOX5 | MAPKAPK2 | 10779545 11844797 14525934 24234451 24860872 25348397 | phosphorylation reaction | experimental interaction detection,physical interaction,protein kinase assay,in vitro | ComPPI,HPRD,IntAct |
PINX1 | MAPKAPK2 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
MAP2K6 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
TRIM28 | MAPKAPK2 | 25348397 | N/A | physical interaction | ComPPI |
HSPB1 | MAPKAPK2 | 11042204 1332886 14525934 21575178 24234451 25241761 25348397 7799959 | phosphorylation reaction,physical association | experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
MAPKAPK2 | TH | 11359875 14525934 25348397 6150037 7901013 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
MAPKAPK2 | BAG2 | 14525934 15271996 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
MAPKAPK2 | EEF2K | 12171600 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
MAPKAPK2 | HNRNPA0 | 12456657 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
MAPKAPK2 | ARPC5 | 12829704 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
MAPKAPK2 | AKT1 | 11042204 14525934 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
MAPKAPK2 | CREB1 | 14525934 25348397 8887554 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
MAPKAPK2 | HSF1 | 14525934 16278218 24234451 25348397 | phosphorylation reaction,physical association | anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
MAPKAPK2 | TCF3 | 10781029 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
MAPKAPK2 | LSP1 | 14525934 25348397 8995217 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
MAPKAPK2 | CSNK2B | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | ESR1 | 21182205 24234451 25348397 | association | cosedimentation through density gradient,physical interaction | ComPPI,IntAct |
MAPKAPK2 | ZFP36L1 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | LIMK1 | 16456544 24234451 25348397 | phosphorylation reaction | physical interaction,protein kinase assay | ComPPI,IntAct |
MAPKAPK2 | CDC25B | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | PARN | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | UBE2J1 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | MAPK11 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
MAPKAPK2 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | STAT3 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
MAPKAPK2 | ATF1 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | AGO2 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | RCSD1 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | CEP131 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | BECN1 | 25348397 | N/A | physical interaction | ComPPI |
MAPKAPK2 | CDC25A | 17292828 24234451 25348397 | phosphorylation reaction | protein kinase assay | ComPPI,IntAct |
LYAR | MAPKAPK2 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
MAPKAPK2 | MAPKAPK2 | 14525934 8846784 | N/A | experimental interaction detection | HPRD |
HSPA1B | MAPKAPK2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
MAPKAPK2 | EWSR1 | 27898060 934118 | N/A | N/A | OmniPath |
MAPKAPK2 | CDC25A | 15629715 17292828 27898060 | inhibition | N/A | OmniPath |
MAPKAPK2 | PLK1 | 18695677 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | TCF3 | 10781029 20626350 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | MAP3K8 | 12138205 15466476 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | CREB1 | 10679065 17389598 20626350 27898060 8887554 | stimulant | N/A | OmniPath |
MAPKAPK2 | CDC25B | 15629715 15908796 27898060 | inhibition | N/A | OmniPath |
MAPKAPK2 | IGFBP1 | 27898060 7678248 | N/A | N/A | OmniPath |
MAPKAPK2 | ELAVL1 | 20626350 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | MDM2 | 15688025 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | REL | 10823840 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | YWHAZ | 11956222 12861023 16376338 19451227 25862939 27898060 | inhibition,stimulant | N/A | OmniPath |
MAPKAPK2 | AGO2 | 20626350 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | CDC25C | 15629715 27898060 | inhibition | N/A | OmniPath |
MAPKAPK2 | HNRNPA0 | 12456657 17287340 20932473 21173571 27898060 | stimulant | N/A | OmniPath |
MAPK3 | MAPKAPK2 | 14499342 14967450 21675959 23583303 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | MAPK14 | 10581204 11042204 15538386 17255097 17395714 19369945 21675959 21988832 23455922 23602568 25241761 25852190 26186194 26496610 27898060 7592979 8846784 9768359 | stimulant | N/A | OmniPath |
MAPK14 | MAPKAPK2 | 10581204 11042204 14499342 15538386 15629715 16456544 17255097 17395714 17906627 18669648 19369945 21675959 21988832 23455922 23602568 25241761 25852190 26186194 26496610 27898060 7592979 7923353 8846784 9768359 | stimulant | N/A | OmniPath |
MAPKAPK2 | HSF1 | 16278218 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | HSPB2 | 18266962 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | ZFP36L1 | 18326031 26280535 27898060 | inhibition | N/A | OmniPath |
MAPKAPK2 | BAG2 | 15271996 19651622 20068231 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | TSC2 | 12582162 15963462 18075516 27898060 | inhibition,stimulant | N/A | OmniPath |
MAPKAPK2 | RPS6KA3 | 18691976 19369195 27898060 | N/A | N/A | OmniPath |
MAPK1 | MAPKAPK2 | 12171911 1327754 15094067 16278218 16456544 20932473 21675959 22128155 27898060 7592979 8846784 | stimulant | N/A | OmniPath |
MAPKAPK2 | PARN | 16964243 18669648 19690332 20932473 21173571 27898060 | inhibition | N/A | OmniPath |
MAPKAPK2 | VIM | 11895474 12761892 15713670 27898060 | stimulant | N/A | OmniPath |
PPP2CA | MAPKAPK2 | 1327754 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | PIAS1 | 23202365 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | ZFP36 | 14688255 15014438 18669648 20599781 27898060 | inhibition,stimulant | N/A | OmniPath |
MAPKAPK2 | AKT2 | 16793766 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | LIMK1 | 16456544 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | HSPB1 | 10383393 11042204 11839738 11844797 12367505 12377770 1332886 14499342 15976317 16097034 16565220 16964243 17081983 17170118 1730670 17924679 18088087 18187866 18212344 18578522 18669648 18691976 18707149 18767875 19007248 19166925 19369195 19413330 19415658 19562805 19651622 19664994 19664995 19691289 20058876 20068231 20166139 20230923 20626350 21575178 25241761 27898060 7799959 8774846 | inhibition,stimulant | N/A | OmniPath |
MAPKAPK2 | SRF | 10318869 10753652 12171911 20626350 27898060 8413226 | stimulant | N/A | OmniPath |
MAPKAPK2 | DDX5 | 23482664 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | TSC1 | 18075516 27898060 | inhibition | N/A | OmniPath |
MAPKAPK2 | PABPC1 | 12565831 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | ARPC5 | 12829704 20068231 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | RAP1B | 1551424 1696481 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | TAB3 | 18021073 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | EEF2K | 12171600 14709557 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | TH | 11359875 1680128 24055376 27898060 6150037 7901013 | stimulant | N/A | OmniPath |
MAPKAPK2 | SPIB | 10618498 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | RTN4 | 16095439 27898060 | N/A | N/A | OmniPath |
PPP2CB | MAPKAPK2 | 1327754 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | EIF2B5 | 11500362 12133000 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | ETV1 | 11551945 20626350 27898060 | inhibition,stimulant | N/A | OmniPath |
MAPKAPK2 | AATF | 22909821 27898060 | stimulant | N/A | OmniPath |
MAPKAPK2 | LSP1 | 17481585 19367720 19413330 20058876 20166139 27898060 8995217 | stimulant | N/A | OmniPath |
MAPKAPK2 | TRIM29 | 24469230 26381412 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | ALOX5 | 10779545 11844797 18978352 24860872 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | RCSD1 | 15850461 19367720 19690332 27898060 | N/A | N/A | OmniPath |
MAPKAPK2 | KRT20 | 16608857 27898060 | N/A | N/A | OmniPath |