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GENE：PGM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PGM1
FullNmae phosphoglucomutase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8905
EnsembleID ENSG00000079739
Uniprot P36871

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PGM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PGM1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PGM1 GO:0000287,GO:0004614,GO:0004614,GO:0004614,GO:0005515,GO:0005576,GO:0005737,GO:0005829,GO:0005829,GO:0005975,GO:0006006,GO:0006006,GO:0006094,GO:0006096,GO:0070062,GO:1904724,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PGM1 hsa:5236 path:hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)
PGM1 hsa:5236 path:hsa00030 Pentose phosphate pathway - Homo sapiens (human)
PGM1 hsa:5236 path:hsa00052 Galactose metabolism - Homo sapiens (human)
PGM1 hsa:5236 path:hsa00230 Purine metabolism - Homo sapiens (human)
PGM1 hsa:5236 path:hsa00500 Starch and sucrose metabolism - Homo sapiens (human)
PGM1 hsa:5236 path:hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human)
PGM1 hsa:5236 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PGM1 hsa:5236 path:hsa01250 Biosynthesis of nucleotide sugars - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PAK1 PGM1 15378030 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,two hybrid,pull down,protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PGM1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PGM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PGM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PGM1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PGM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 PGM1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000324096 PGM1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PAK1 PGM1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
LDHB PGM1 25348397 N/A physical interaction ComPPI
LDHA PGM1 25348397 N/A physical interaction ComPPI
S100B PGM1 14525934 25348397 8894274 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
S100A1 PGM1 14525934 25348397 8894274 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PAK1 PGM1 25348397 N/A two hybrid,physical interaction ComPPI
PAXIP1 PGM1 25348397 N/A physical interaction ComPPI
PGM1 UBA5 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PGM1 TERF1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PGM1 TERF2IP 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PGM1 TINF2 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PGM1 POT1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PGM1 USP4 25348397 N/A physical interaction ComPPI
PGM1 APP 25348397 N/A physical interaction ComPPI
PGM1 TALDO1 25348397 N/A physical interaction ComPPI
PGM1 PGM2 25348397 N/A physical interaction ComPPI
PGM1 FUBP1 25348397 N/A physical interaction ComPPI
PGM1 GRHPR 25348397 N/A physical interaction ComPPI
PGM1 MDH1 25348397 N/A physical interaction ComPPI
PGM1 FH 25348397 N/A physical interaction ComPPI
PGM1 NIT2 25348397 N/A physical interaction ComPPI
PGM1 FUS 25348397 N/A physical interaction ComPPI
PGM1 ATIC 25348397 N/A physical interaction ComPPI
PGM1 CAT 25348397 N/A physical interaction ComPPI
PGM1 ENO1 25348397 N/A physical interaction ComPPI
PGM1 EXOC2 25348397 N/A physical interaction ComPPI
PGM1 GALK2 25348397 N/A physical interaction ComPPI
PGM1 GPI 25348397 N/A physical interaction ComPPI
PGM1 LTA4H 25348397 N/A physical interaction ComPPI
PGM1 ABAT 25348397 N/A physical interaction ComPPI
PGM1 ABHD11 25348397 N/A physical interaction ComPPI
PGM1 ALDH1B1 25348397 N/A physical interaction ComPPI
PGM1 ALDH2 25348397 N/A physical interaction ComPPI
PGM1 KYAT3 25348397 N/A physical interaction ComPPI
PGM1 FAH 25348397 N/A physical interaction ComPPI
PGM1 GPD1L 25348397 N/A physical interaction ComPPI
PGM1 OAT 25348397 N/A physical interaction ComPPI
PGM1 SOD1 25348397 N/A physical interaction ComPPI
PGM1 SORD 25348397 N/A physical interaction ComPPI
PGM1 UQCRFS1 25348397 N/A physical interaction ComPPI
PGM1 PGM3 25348397 N/A physical interaction ComPPI
PGM1 PRDX6 25348397 N/A physical interaction ComPPI
PGM1 SCCPDH 25348397 N/A physical interaction ComPPI
PGM1 TPI1 25348397 N/A physical interaction ComPPI
PGM1 NTRK1 25348397 N/A physical interaction ComPPI
PGM1 HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
PGM1 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PGM1 ENO3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
KIF1B PGM1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
HSCB PGM1 24234451 24606901 25348397 physical association two hybrid ComPPI,IntAct
ARM PGM1 24234451 25294943 25348397 association pull down ComPPI,IntAct
CI PGM1 15710747 24234451 25348397 physical association physical interaction,two hybrid fragment pooling approach ComPPI,IntAct
PAK1 PGM1 15378030 27898060 stimulant N/A OmniPath
PKN1 PGM1 15378030 27898060 stimulant N/A OmniPath

Visualization










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