Gene Information gene info

  1. Home

GENE：SNX6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SNX6
FullNmae sorting nexin 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14970
EnsembleID ENSG00000129515
Uniprot Q9UNH7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SNX6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SNX6 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SNX6 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SNX6 GO:0005515,GO:0005634,GO:0005737,GO:0005764,GO:0005768,GO:0005768,GO:0005829,GO:0006886,GO:0006886,GO:0007175,GO:0016241,GO:0030512,GO:0030904,GO:0030905,GO:0031901,GO:0034452,GO:0034452,GO:0034713,GO:0035091,GO:0042147,GO:0042147,GO:0042147,GO:0042803,GO:0043524,GO:0045892,GO:0071364,GO:0097422,GO:0098978,GO:0099072,GO:1904646

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SNX6 hsa:58533 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TPT1 SNX6 16730713 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
SNX6 BMPR1B 20005715 interaction type N/A PSP
SNX6 INSR 20005715 interaction type N/A PSP
SNX6 PDGFRA 20005715 interaction type N/A PSP
SNX6 TGFBR1 20005715 interaction type N/A PSP
SNX6 ACVRL1 20005715 interaction type N/A PSP
SNX6 TGFBR2 20005715 interaction type N/A PSP
SNX6 TGFBR1 20005715 N/A N/A SignaLink
SNX6 TGFBR2 11279102 18988627 20005715 N/A N/A SignaLink
SNX6 ACVRL1 11279102 18988627 20005715 20005715 N/A N/A SignaLink
SNX6 BMPR1B 11279102 18988627 20005715 20005715 N/A N/A SignaLink
SNX6 INSR 11279102 18988627 20005715 20005715 N/A N/A SignaLink
SNX6 PDGFRA 11279102 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 SNX6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SNX6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SNX6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SNX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 SNX6 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000021D7C8 SNX6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 SNX6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000122ED0 SNX6 25416803 27541017 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SNX6 PIM1 25361965 interaction type N/A PTMCode2
PIM1 SNX6 25361965 interaction type N/A PTMCode2
LEPR SNX6 25361965 interaction type N/A PTMCode2
SNX6 LEPR 25361965 interaction type N/A PTMCode2
SNX4 SNX6 25361965 interaction type N/A PTMCode2
SNX6 SNX4 25361965 interaction type N/A PTMCode2
ACVR2B SNX6 25361965 interaction type N/A PTMCode2
SNX6 ACVR2B 25361965 interaction type N/A PTMCode2
TGFBR2 SNX6 25361965 interaction type N/A PTMCode2
SNX6 TGFBR2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TSNAX SNX6 25348397 N/A physical interaction ComPPI
IMPDH2 SNX6 25348397 N/A physical interaction ComPPI
COIL SNX6 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
STAT1 SNX6 25348397 N/A physical interaction ComPPI
GTF2A1 SNX6 25348397 N/A physical interaction ComPPI
CALM1 SNX6 25348397 N/A physical interaction ComPPI
BRMS1 SNX6 20830743 25348397 27898060 N/A physical interaction ComPPI,OmniPath
OPTN SNX6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
TGFBR2 SNX6 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PIM1 SNX6 11279102 11591366 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
JUN SNX6 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PDGFRA SNX6 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GIT1 SNX6 18523162 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SNX1 SNX6 11279102 14525934 21988832 23524952 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
SNX2 SNX6 11279102 14525934 21988832 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
SNX6 LEPR 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNX6 ACVRL1 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNX6 ACVR2B 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNX6 BMPR1B 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNX6 TPT1 14525934 16730713 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
SNX6 EGFR 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNX6 INSR 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNX6 SNX4 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SNX6 TGFBR1 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SNX6 DISC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNX6 NDEL1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNX6 TNIK 25348397 N/A physical interaction ComPPI
SNX6 ELAVL1 25348397 N/A physical interaction ComPPI
SNX6 PHLPP1 25348397 N/A physical interaction ComPPI
SNX6 BRCA1 25348397 N/A physical interaction ComPPI
SNX6 RTF1 25348397 N/A physical interaction ComPPI
SNX6 ANP32E 25348397 N/A physical interaction ComPPI
SNX6 ATG7 25348397 N/A physical interaction ComPPI
SNX6 NIBAN2 25348397 N/A physical interaction ComPPI
SNX6 PAWR 25348397 N/A physical interaction ComPPI
SNX6 SHMT1 25348397 N/A physical interaction ComPPI
SNX6 SHMT2 25348397 N/A physical interaction ComPPI
SNX6 VPS29 25348397 N/A physical interaction ComPPI
SNX6 TSN 25348397 N/A physical interaction ComPPI
SNX6 ESR1 25348397 N/A physical interaction ComPPI
SNX6 USP46 25348397 N/A physical interaction ComPPI
SNX6 FAM221A 25348397 N/A physical interaction ComPPI
SNX6 DNM3 25348397 N/A physical interaction ComPPI
SNX6 TEAD4 25348397 N/A physical interaction ComPPI
SNX6 TREML2 25348397 N/A physical interaction ComPPI
SNX6 FAM43A 25348397 N/A physical interaction ComPPI
SNX6 CAMKMT 25348397 N/A physical interaction ComPPI
SNX6 CCNL2 25348397 N/A physical interaction ComPPI
SNX6 CASTOR3 25348397 N/A physical interaction ComPPI
SNX6 VAPB 25348397 N/A physical interaction ComPPI
SNX6 PCID2 25348397 N/A physical interaction ComPPI
SNX6 IFI16 25348397 N/A physical interaction ComPPI
SNX6 HERC2 25348397 N/A physical interaction ComPPI
SNX6 HERC2P3 25348397 N/A physical interaction ComPPI
SNX6 PTPRR 25348397 N/A physical interaction ComPPI
SNX6 MTM1 25348397 N/A physical interaction ComPPI
SNX6 SNX32 25348397 N/A physical interaction ComPPI
SNX6 POTEB3 25348397 N/A physical interaction ComPPI
SNX6 TSPYL1 25348397 N/A physical interaction ComPPI
SNX6 DYNLT2B 25348397 N/A physical interaction ComPPI
SNX6 CCDC102B 25348397 N/A physical interaction ComPPI
SNX6 USP47 25348397 N/A physical interaction ComPPI
SNX6 FGB 25348397 N/A physical interaction ComPPI
SNX6 EPB42 25348397 N/A physical interaction ComPPI
SNX6 DCTN1 23524952 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SNX6 ATP1A1 16730713 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SNX6 TRAF3IP1 17043677 24234451 25348397 physical association two hybrid ComPPI,IntAct
SNX6 SNX7 23085988 24234451 25348397 physical association pull down ComPPI,IntAct
SNX6 GOLM1 24234451 25348397 27569582 association anti tag coimmunoprecipitation ComPPI,IntAct
SNX6 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SNX6 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SNX6 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SNX6 RAB9A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SNX6 TGOLN2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
SNX6 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CSNK2A2 SNX6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
H3-3A SNX6 25348397 N/A physical interaction ComPPI
VPS35 SNX6 25348397 N/A physical interaction ComPPI
APEH SNX6 25348397 N/A physical interaction ComPPI
SNRNP27 SNX6 25348397 N/A physical interaction ComPPI
ATP6V1C1 SNX6 25348397 N/A physical interaction ComPPI
HENMT1 SNX6 25348397 N/A physical interaction ComPPI
SNX6 SNX6 11279102 14525934 N/A experimental interaction detection HPRD

Visualization










  Return