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GENE：ATP6V1E1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6V1E1
FullNmae ATPase H+ transporting V1 subunit E1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:857
EnsembleID ENSG00000131100
Uniprot P36543

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6V1E1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V1E1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V1E1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP6V1E1 GO:0000221,GO:0005515,GO:0005765,GO:0005768,GO:0005829,GO:0005829,GO:0005902,GO:0016241,GO:0016324,GO:0016469,GO:0030665,GO:0030672,GO:0046961,GO:0051117,GO:0070062,GO:0097401,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6V1E1 hsa:529 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa04966 Collecting duct acid secretion - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6V1E1 hsa:529 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ATP6V1E1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ATP6V1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP6V1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP6V1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATP6V1E1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ATP6V1E1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 ATP6V1E1 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS000035CC3E ATP6V1E1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 ATP6V1E1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000012A1DD ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000171525 ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000081D1E ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EED18 ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C7B2B ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001310DE ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000055BBE5 ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001481F9 ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001F5B39 ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003758F0 ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032D69B ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000122F23 ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000023133F ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F859B ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045E0EC ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075BDAA ATP6V1E1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP6V1G1 ATP6V1E1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AIMP2 ATP6V1E1 25348397 N/A physical interaction ComPPI
YES1 ATP6V1E1 25348397 N/A physical interaction ComPPI
TRAF6 ATP6V1E1 14525934 16196101 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SOS1 ATP6V1E1 11560919 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
JUN ATP6V1E1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SLC9A3R1 ATP6V1E1 10748165 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
VAPA ATP6V1E1 25348397 N/A physical interaction ComPPI
YBX1 ATP6V1E1 25348397 N/A physical interaction ComPPI
SSBP1 ATP6V1E1 25348397 N/A physical interaction ComPPI
LAMTOR3 ATP6V1E1 25348397 N/A physical interaction ComPPI
XRCC6 ATP6V1E1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PSG9 ATP6V1E1 25348397 N/A physical interaction ComPPI
ZFP36 ATP6V1E1 25348397 N/A physical interaction ComPPI
ABCC2 ATP6V1E1 25348397 N/A physical interaction ComPPI
ATP6AP2 ATP6V1E1 25348397 N/A physical interaction ComPPI
ATP1B1 ATP6V1E1 25348397 N/A physical interaction ComPPI
ALDOB ATP6V1E1 11399750 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ATP6V1E1 ALDOA 11399750 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
ATP6V1E1 MESD 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP6V1E1 APP 25348397 N/A physical interaction ComPPI
ATP6V1E1 ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V1E1 PPIF 25348397 N/A physical interaction ComPPI
ATP6V1E1 SCAMP3 25348397 N/A physical interaction ComPPI
ATP6V1E1 ZFR 25348397 N/A physical interaction ComPPI
ATP6V1E1 SCO2 25348397 N/A physical interaction ComPPI
ATP6V1E1 SRSF3 25348397 N/A physical interaction ComPPI
ATP6V1E1 ZNF827 25348397 N/A physical interaction ComPPI
ATP6V1E1 ALYREF 25348397 N/A physical interaction ComPPI
ATP6V1E1 SFXN1 25348397 N/A physical interaction ComPPI
ATP6V1E1 S100A10 25348397 N/A physical interaction ComPPI
ATP6V1E1 TYMS 25348397 N/A physical interaction ComPPI
ATP6V1E1 THY1 25348397 N/A physical interaction ComPPI
ATP6V1E1 SUGP1 25348397 N/A physical interaction ComPPI
ATP6V1E1 CD55 25348397 N/A physical interaction ComPPI
ATP6V1E1 SAMHD1 25348397 N/A physical interaction ComPPI
ATP6V1E1 HMGCS1 25348397 N/A physical interaction ComPPI
ATP6V1E1 NDUFS8 25348397 N/A physical interaction ComPPI
ATP6V1E1 HSPB2 25348397 N/A physical interaction ComPPI
ATP6V1E1 MED20 25348397 N/A physical interaction ComPPI
ATP6V1E1 GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP6V1E1 DEDD 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
ATP6V1E1 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1E1 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ALDOC ATP6V1E1 25348397 N/A physical interaction ComPPI
COX4I1 ATP6V1E1 25348397 N/A physical interaction ComPPI
ATP6V1B2 ATP6V1E1 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009B4F54 ATP6V1E1 27087310 direct interaction,inhibition N/A NPInter

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