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GENE：DRAM2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DRAM2
FullNmae DNA damage regulated autophagy modulator 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28769
EnsembleID ENSG00000156171
Uniprot Q6UX65

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DRAM2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DRAM2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
DRAM2 GO:0001917,GO:0005737,GO:0005764,GO:0005764,GO:0005765,GO:0005794,GO:0006914,GO:0006915,GO:0007601,GO:0010506,GO:0010506,GO:0016324,GO:0043231,GO:0045494,GO:0045494

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 DRAM2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DRAM2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA DRAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DRAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DRAM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065FDF DRAM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 DRAM2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ELAVL1 DRAM2 25348397 N/A physical interaction ComPPI

Visualization










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