GENE：TRIM22
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TRIM22 |
| FullNmae | tripartite motif containing 22 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16379 |
| EnsembleID | ENSG00000132274 |
| Uniprot | Q8IYM9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TRIM22 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TRIM22 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TRIM22 | GO:0000209,GO:0002230,GO:0003713,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005794,GO:0005829,GO:0005829,GO:0006355,GO:0006955,GO:0008270,GO:0009615,GO:0010508,GO:0010508,GO:0015030,GO:0016567,GO:0016604,GO:0016607,GO:0019901,GO:0019901,GO:0030674,GO:0032880,GO:0032880,GO:0042802,GO:0042803,GO:0043123,GO:0043123,GO:0045087,GO:0045892,GO:0045893,GO:0046596,GO:0051091,GO:0051092,GO:0051092,GO:0051607,GO:0061630,GO:0061630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TP73 | TRIM22 | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| FOXP3 | TRIM22 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | TRIM22 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TRIM22 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TRIM22 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | TRIM22 | 15064739 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREBBP | TRIM22 | 23670564 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EP300 | TRIM22 | 23670564 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| IRF1 | TRIM22 | 21683060 23670564 23729439 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | TRIM22 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001EFBE3 | TRIM22 | 18057241 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000003ABC4 | TRIM22 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LGALS3 | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| TP53BP1 | TRIM22 | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| USP7 | TRIM22 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid | ComPPI,HPRD,IntAct |
| CASK | TRIM22 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| CIITA | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| CCNT1 | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| CHUK | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| LGALS8 | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| TAB2 | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| CIC | TRIM22 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid | ComPPI,HPRD,IntAct |
| TAF7 | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| PML | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| EIF4E | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| RERE | TRIM22 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid | ComPPI,HPRD,IntAct |
| CREB1 | TRIM22 | 25348397 | N/A | physical interaction | ComPPI |
| TP53 | TRIM22 | 18431400 27898060 | stimulant | N/A | OmniPath |