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GENE：EPM2A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EPM2A
FullNmae EPM2A glucan phosphatase, laforin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3413
EnsembleID ENSG00000112425
Uniprot B3EWF7|O95278

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EPM2A autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EPM2A autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
EPM2A GO:0005515,GO:0005634,GO:0016239,GO:0032007

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR EPM2A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 EPM2A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 EPM2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 EPM2A N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC EPM2A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 EPM2A 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 EPM2A 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D EPM2A 18591254 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA1 EPM2A 22135298 phosphorylation N/A PhosphoSite
EPM2A EPM2AIP1 25361965 interaction type N/A PTMCode2
EPM2AIP1 EPM2A 25361965 interaction type N/A PTMCode2
GSK3B EPM2A 25361965 interaction type N/A PTMCode2
EPM2A GSK3B 25361965 interaction type N/A PTMCode2
GYS1 EPM2A 25361965 interaction type N/A PTMCode2
EPM2A GYS1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PRKAA2 EPM2A 25348397 N/A physical interaction ComPPI
EPM2AIP1 EPM2A 12782127 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PSMC3 EPM2A 25348397 N/A physical interaction ComPPI
COX5A EPM2A 25348397 N/A physical interaction ComPPI
STBD1 EPM2A 25348397 N/A physical interaction ComPPI
PPP1R3C EPM2A 14532330 24234451 25348397 colocalization,physical association two hybrid,fluorescence technology,pull down,physical interaction ComPPI,IntAct
RPL10 EPM2A 25348397 N/A physical interaction ComPPI
RPL10 EPM2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
TDG EPM2A 25348397 N/A physical interaction ComPPI
GSK3B EPM2A 25348397 N/A physical interaction ComPPI
PRKAA1 EPM2A 25348397 N/A physical interaction ComPPI
UBE2N EPM2A 25348397 N/A physical interaction ComPPI
SQSTM1 EPM2A 25348397 N/A physical interaction ComPPI
PKM EPM2A 25348397 N/A physical interaction ComPPI
TOPORS EPM2A 25348397 N/A physical interaction ComPPI
UBA1 EPM2A 15930137 24234451 25348397 physical association ubiquitinase assay ComPPI,IntAct
NFU1 EPM2A 12915448 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
EIF2B1 EPM2A 25348397 N/A physical interaction ComPPI
SRPK2 EPM2A 25348397 N/A physical interaction ComPPI
STUB1 EPM2A 25348397 N/A physical interaction ComPPI
PRKAB2 EPM2A 25348397 N/A physical interaction ComPPI
PPP1R3D EPM2A 25348397 N/A physical interaction ComPPI
GYS1 EPM2A 14532330 24234451 25348397 colocalization fluorescence technology ComPPI,IntAct
EPM2A NHLRC1 15930137 21505799 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,confocal microscopy,ubiquitinase assay ComPPI,IntAct
EPM2A HMGXB4 25348397 N/A physical interaction ComPPI
EPM2A OTUB1 25348397 N/A physical interaction ComPPI
OTUB1 EPM2A 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
EPM2A EPM2A 14532330 24234451 physical association two hybrid IntAct
EPM2A PPP1R3D 23624058 27898060 N/A N/A OmniPath
EPM2A EPM2AIP1 12782127 27898060 N/A N/A OmniPath
PRKAA2 EPM2A 21728993 27898060 N/A N/A OmniPath
EPM2A GSK3B 16959610 27898060 N/A N/A OmniPath
PRKAA1 EPM2A 21728993 27898060 N/A N/A OmniPath
EPM2A NFU1 12915448 27898060 inhibition N/A OmniPath

Visualization










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