Gene Information gene info

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GENE：EXOC7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EXOC7
FullNmae exocyst complex component 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23214
EnsembleID ENSG00000182473
Uniprot Q9UPT5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EXOC7 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EXOC7 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
EXOC7 GO:0000145,GO:0000145,GO:0000281,GO:0005515,GO:0005546,GO:0005815,GO:0005829,GO:0005886,GO:0006887,GO:0006904,GO:0015031,GO:0016020,GO:0016241,GO:0032584,GO:0034451,GO:0090148,GO:0090522,GO:0090543,GO:2000535

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EXOC7 hsa:23265 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
EXOC7 hsa:23265 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 EXOC7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 EXOC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EXOC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EXOC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EXOC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EXOC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EXOC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EXOC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 EXOC7 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 EXOC7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E EXOC7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC EXOC7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005E1A16 EXOC7 21572407 22012620 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 EXOC7 21572407 22012620 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDCD1 EXOC7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 EXOC7 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK3 EXOC7 22135298 phosphorylation N/A PhosphoSite
MAPK1 EXOC7 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
EXOC5 EXOC7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
SNW1 EXOC7 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC73 EXOC7 25348397 N/A physical interaction ComPPI
SMARCE1 EXOC7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDC5L EXOC7 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
STX11 EXOC7 25348397 N/A physical interaction ComPPI
KIF5B EXOC7 25348397 N/A physical interaction ComPPI
EXOC8 EXOC7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RAMAC EXOC7 25348397 N/A physical interaction ComPPI
CCDC85B EXOC7 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BBS2 EXOC7 18000879 24234451 25348397 physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
KXD1 EXOC7 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HGS EXOC7 14525934 16189514 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
NTRK1 EXOC7 25348397 N/A physical interaction ComPPI
RHOQ EXOC7 12687004 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
CFTR EXOC7 25348397 N/A physical interaction ComPPI
EXOC1 EXOC7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC3 EXOC7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC2 EXOC7 14525934 14525976 24234451 25348397 physical association experimental interaction detection,physical interaction,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
EXOC4 EXOC7 12687004 14525934 21241894 24234451 25348397 27173435 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
EPHA1 EXOC7 25348397 N/A physical interaction ComPPI
GRIN2B EXOC7 25348397 N/A physical interaction ComPPI
EGFR EXOC7 24234451 25348397 25594178 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
ABI2 EXOC7 25348397 N/A physical interaction ComPPI
DLG3 EXOC7 25348397 N/A physical interaction ComPPI
RIOX2 EXOC7 25348397 N/A physical interaction ComPPI
TRAF4 EXOC7 25348397 N/A physical interaction ComPPI
CD274 EXOC7 25348397 N/A physical interaction ComPPI
BBS4 EXOC7 18000879 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
FCGRT EXOC7 25348397 N/A physical interaction ComPPI
CAVIN1 EXOC7 25348397 N/A physical interaction ComPPI
DTNBP1 EXOC7 25348397 N/A physical interaction ComPPI
IFT57 EXOC7 25348397 N/A physical interaction ComPPI
IFT20 EXOC7 14525934 16189514 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
DSN1 EXOC7 25348397 N/A physical interaction ComPPI
AKTIP EXOC7 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SHMT2 EXOC7 25348397 N/A physical interaction ComPPI
RTN4IP1 EXOC7 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PRPF19 EXOC7 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
USHBP1 EXOC7 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TSKS EXOC7 25348397 N/A physical interaction ComPPI
PNKD EXOC7 25348397 N/A physical interaction ComPPI
ZC3H14 EXOC7 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
IL1R2 EXOC7 25348397 N/A physical interaction ComPPI
DISC1 EXOC7 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EXOC7 BBS1 18000879 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
EXOC7 SSC5D 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EXOC7 MOV10 25348397 N/A physical interaction ComPPI
EXOC7 NXF1 25348397 N/A physical interaction ComPPI
EXOC7 CA14 25348397 N/A physical interaction ComPPI
EXOC7 SCN2B 25348397 N/A physical interaction ComPPI
EXOC7 EXOC6 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC7 EXOC6B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC7 COG6 25348397 N/A physical interaction ComPPI
EXOC7 SIGLECL1 25348397 N/A physical interaction ComPPI
EXOC7 POC1B 25348397 N/A physical interaction ComPPI
EXOC7 BBS7 18000879 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
EXOC7 ARFGEF2 14525934 15705715 24234451 25348397 27898060 colocalization cosedimentation through density gradient,imaging technique,two hybrid ComPPI,HPRD,IntAct,OmniPath
EXOC7 LAPTM4B 24234451 25348397 25594178 colocalization,physical association anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
EXOC7 RALA 11406615 14525934 N/A experimental interaction detection HPRD
EXOC7 ARPC1A 14525934 17086175 27898060 N/A experimental interaction detection HPRD,OmniPath
HNRNPU EXOC7 24234451 30021884 physical association cross-linking study IntAct
MAPK3 EXOC7 22595671 27898060 N/A N/A OmniPath
MAPK1 EXOC7 22595671 27898060 stimulant N/A OmniPath
RHOQ EXOC7 12687004 27898060 stimulant N/A OmniPath

Visualization










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