Gene Information gene info

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GENE：DRAM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DRAM1
FullNmae DNA damage regulated autophagy modulator 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25645
EnsembleID ENSG00000136048
Uniprot Q8N682

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DRAM1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DRAM1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DRAM1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
DRAM1 GO:0005515,GO:0005737,GO:0005764,GO:0005764,GO:0005765,GO:0006914,GO:0006915,GO:0010506,GO:0010506

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DRAM1 E2F1 18408756 23180781 physical association anti tag coimmunoprecipitation InnateDB
E2F4 DRAM1 18408756 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 DRAM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DRAM1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DRAM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C DRAM1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DRAM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DRAM1 18408756 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000018C928 DRAM1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 DRAM1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TIMMDC1 DRAM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CREB3 DRAM1 25348397 N/A physical interaction ComPPI
LRRC4C DRAM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A7 DRAM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APP DRAM1 25348397 N/A physical interaction ComPPI
DRAM1 CLRN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DRAM1 GPR42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
C1ORF21 DRAM1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

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