Gene Information gene info

GENE:RNF5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNF5
FullNmae ring finger protein 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10068
EnsembleID ENSG00000204308
Uniprot Q99942

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNF5 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RNF5 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RNF5 GO:0004842,GO:0005515,GO:0005783,GO:0005789,GO:0005886,GO:0006511,GO:0008270,GO:0009617,GO:0010507,GO:0030163,GO:0030433,GO:0031648,GO:0031966,GO:0036503,GO:0042802,GO:0044390,GO:0044877,GO:0055085,GO:0061630,GO:0061630,GO:0070534,GO:0070936,GO:0071712,GO:0071712,GO:2000785

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RNF5 hsa:6048 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
STING1 RNF5 19285439 23180781 physical association anti tag coimmunoprecipitation InnateDB
DDX58 RNF5 19285439 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAVS RNF5 19285439 23180781 physical association anti tag coimmunoprecipitation InnateDB
JKAMP RNF5 19269966 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 RNF5 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RNF5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 RNF5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RNF5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RNF5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RNF5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RNF5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE RNF5 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SEC22A RNF5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNFAIP3 RNF5 25348397 N/A physical interaction ComPPI
UBE2D1 RNF5 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YIPF4 RNF5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E2 RNF5 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBTD1 RNF5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 TMEM242 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 INSIG2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 UBE2E1 14525934 14667819 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
RNF5 UBE2D2 14525934 14667819 19549727 20152160 24234451 25348397 27898060 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct,OmniPath
RNF5 UBE2D3 14525934 14667819 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
RNF5 FHOD1 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RNF5 MPDZ 10967549 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
RNF5 ABHD16A 14525934 14667819 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
RNF5 PXN 12861019 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
RNF5 CFTR 14525934 16901789 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo ComPPI,HPRD,IntAct
RNF5 AMFR 25348397 N/A physical interaction ComPPI
RNF5 UBE2U 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF5 UBE2K 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 UBE2V1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF5 UBE2W 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF5 MAVS 25348397 N/A physical interaction ComPPI
RNF5 JKAMP 25348397 N/A physical interaction ComPPI
RNF5 STING1 25348397 N/A physical interaction ComPPI
RNF5 DERL1 16901789 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 UBE2J1 16901789 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 BCAP31 18555783 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 UBE2N 25348397 N/A physical interaction ComPPI
RNF5 UBE2G2 25348397 N/A physical interaction ComPPI
RNF5 UBC 25348397 N/A physical interaction,physical interaction,comigration in sds page ComPPI
RNF5 ADRB2 25348397 N/A physical interaction ComPPI
RNF5 CYB561 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 SLC38A7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 RNF185 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 CYB561A3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RNF5 DNAJC7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 XRCC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 TOMM40 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 ATL3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 TUBA1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF5 ERLIN2 25348397 N/A physical interaction ComPPI
RNF5 BAG6 25348397 N/A physical interaction ComPPI
RNF5 UBA52 25348397 N/A physical interaction,comigration in sds page ComPPI
RNF5 SLC38A2 24234451 25348397 25759021 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
RNF5 SLC1A5 24234451 25348397 25759021 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
RNF5 ARL6IP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 MS4A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 RABAC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 PRAF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 RUSF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 LEPROTL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 YIPF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 ORMDL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 SCD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 PLP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 RHBDD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 PLPP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 DGAT2L6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC1A1 RNF5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2E3 RNF5 14525934 14667819 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
YIPF2 RNF5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2D4 RNF5 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBB RNF5 25348397 N/A physical interaction,comigration in sds page ComPPI
RPS27A RNF5 25348397 N/A physical interaction,comigration in sds page ComPPI
TMEM120B RNF5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF5 TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD
RNF5 RNF5 24234451 25416956 physical association two hybrid array,two hybrid prey pooling approach IntAct
CLN6 RNF5 24234451 30177828 association anti tag coimmunoprecipitation IntAct
MAVS RNF5 19285439 20483786 27898060 N/A N/A OmniPath
RNF5 MAVS 19285439 20483786 27898060 N/A N/A OmniPath
DDX58 RNF5 19285439 27898060 N/A N/A OmniPath
RNF5 STING1 19285439 27898060 N/A N/A OmniPath

Visualization