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GENE：ATP6V0A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6V0A1
FullNmae ATPase H+ transporting V0 subunit a1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:865
EnsembleID ENSG00000033627
Uniprot Q93050

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6V0A1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V0A1 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
ATP6V0A1 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
ATP6V0A1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V0A1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP6V0A1 GO:0000220,GO:0005515,GO:0005765,GO:0005794,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0007035,GO:0007035,GO:0007042,GO:0010008,GO:0016020,GO:0016241,GO:0016471,GO:0016607,GO:0030665,GO:0030667,GO:0030670,GO:0030672,GO:0033176,GO:0042470,GO:0043231,GO:0046961,GO:0048388,GO:0048471,GO:0051117,GO:0051117,GO:0070062,GO:0097401,GO:0101003,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6V0A1 hsa:535 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa04142 Lysosome - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa04966 Collecting duct acid secretion - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa05152 Tuberculosis - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6V0A1 hsa:535 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ATP6V0A1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ATP6V0A1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ATP6V0A1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ATP6V0A1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ATP6V0A1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 ATP6V0A1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ATP6V0A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 ATP6V0A1 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000324096 ATP6V0A1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000237AF9 ATP6V0A1 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
ATP6V0A1 RFC4 25361965 interaction type N/A PTMCode2
RFC4 ATP6V0A1 25361965 interaction type N/A PTMCode2
ATP6V0A1 RFC5 25361965 interaction type N/A PTMCode2
RFC5 ATP6V0A1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ATP6V1D ATP6V0A1 25348397 N/A physical interaction ComPPI
HOXB5 ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP5PO ATP6V0A1 25348397 N/A physical interaction ComPPI
TMEM199 ATP6V0A1 25348397 N/A physical interaction ComPPI
VAMP2 ATP6V0A1 25348397 N/A physical interaction ComPPI
LDHB ATP6V0A1 24234451 25348397 27622334 physical association anti bait coimmunoprecipitation,proximity ligation assay ComPPI,IntAct
RPS15 ATP6V0A1 25348397 N/A physical interaction ComPPI
BORCS6 ATP6V0A1 25348397 N/A physical interaction ComPPI
CD4 ATP6V0A1 25348397 N/A physical interaction ComPPI
NONO ATP6V0A1 25348397 N/A physical interaction ComPPI
RAB7A ATP6V0A1 25348397 N/A physical interaction ComPPI
CTSD ATP6V0A1 20541250 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
NTRK1 ATP6V0A1 25348397 N/A physical interaction ComPPI
PTPN1 ATP6V0A1 25348397 N/A physical interaction ComPPI
PA2G4 ATP6V0A1 25348397 N/A physical interaction ComPPI
PTGIR ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6AP2 ATP6V0A1 25348397 N/A physical interaction ComPPI
CLTC ATP6V0A1 25348397 N/A physical interaction ComPPI
RPS18 ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V1B1 ATP6V0A1 20541250 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
LGALS8 ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V1E1 ATP6V0A1 25348397 N/A physical interaction ComPPI
CLIC1 ATP6V0A1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NUFIP1 ATP6V0A1 25348397 N/A physical interaction ComPPI
SRSF3 ATP6V0A1 25348397 N/A physical interaction ComPPI
PTRH2 ATP6V0A1 25348397 N/A physical interaction ComPPI
TFG ATP6V0A1 25348397 N/A physical interaction ComPPI
BCAM ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V1A ATP6V0A1 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MARCKSL1 ATP6V0A1 25348397 N/A physical interaction ComPPI
SCFD1 ATP6V0A1 25348397 N/A physical interaction ComPPI
HTR3A ATP6V0A1 25348397 N/A physical interaction ComPPI
RAB5C ATP6V0A1 25348397 N/A physical interaction ComPPI
RGS20 ATP6V0A1 25348397 N/A physical interaction ComPPI
CHMP4B ATP6V0A1 25348397 N/A physical interaction ComPPI
GNAZ ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V0E1 ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V0D1 ATP6V0A1 25348397 N/A physical interaction ComPPI
MRPL44 ATP6V0A1 25348397 N/A physical interaction ComPPI
HLA-DQA1 ATP6V0A1 25348397 N/A physical interaction ComPPI
MTUS2 ATP6V0A1 25348397 N/A physical interaction ComPPI
SLC25A3 ATP6V0A1 25348397 N/A physical interaction ComPPI
MGST3 ATP6V0A1 25348397 N/A physical interaction ComPPI
TMEM216 ATP6V0A1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TMEM67 ATP6V0A1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6V0A2 ATP6V0A1 25348397 N/A physical interaction ComPPI
MCAM ATP6V0A1 25348397 N/A physical interaction ComPPI
SNX4 ATP6V0A1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MEAK7 ATP6V0A1 25348397 N/A physical interaction ComPPI
MUC1 ATP6V0A1 25348397 N/A physical interaction ComPPI
SEH1L ATP6V0A1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF19B ATP6V0A1 25348397 N/A physical interaction ComPPI
MRPL46 ATP6V0A1 25348397 N/A physical interaction ComPPI
MRPL50 ATP6V0A1 25348397 N/A physical interaction ComPPI
GOLT1B ATP6V0A1 25348397 N/A physical interaction ComPPI
KIAA2013 ATP6V0A1 25348397 N/A physical interaction ComPPI
SLC30A5 ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V0D2 ATP6V0A1 25348397 N/A physical interaction ComPPI
FAM131B ATP6V0A1 25348397 N/A physical interaction ComPPI
TCTN3 ATP6V0A1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6V0A1 ZNF267 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ATP6V0A1 CEACAM21 25348397 N/A physical interaction ComPPI
ATP6V0A1 TMEM185A 25348397 N/A physical interaction ComPPI
ATP6V0A1 SERINC2 25348397 N/A physical interaction ComPPI
ATP6V0A1 SLC34A2 25348397 N/A physical interaction ComPPI
ATP6V0A1 ADGRG5 25348397 N/A physical interaction ComPPI
ATP6V0A1 SMPD3 25348397 N/A physical interaction ComPPI
ATP6V0A1 TMEM63A 25348397 N/A physical interaction ComPPI
ATP6V0A1 SLC35D3 25348397 N/A physical interaction ComPPI
ATP6V0A1 FZD10 25348397 N/A physical interaction ComPPI
HRH1 ATP6V0A1 24234451 28298427 physical association ubiquitin reconstruction IntAct

Source Target Pmid Interactiontype Methods Database
URS00008BA5FD ATP6V0A1 27087310 direct interaction,inhibition N/A NPInter

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