Gene Information gene info

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GENE：WAC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WAC
FullNmae WW domain containing adaptor with coiled-coil
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17327
EnsembleID ENSG00000095787
Uniprot Q9BTA9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WAC parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WAC immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WAC autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WAC autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WAC autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
WAC GO:0000993,GO:0000993,GO:0003682,GO:0003682,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005681,GO:0006338,GO:0006974,GO:0010506,GO:0016239,GO:0016607,GO:0031571,GO:0032435,GO:0045893,GO:1904263

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 WAC 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 WAC 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 WAC 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 WAC 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE WAC 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000A057E WAC 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C WAC 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 WAC 21572407 22012620 23592263 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS0000042E1F WAC 21572407 22012620 23592263 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000035CC3E WAC 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA WAC 21572407 22012620 23592263 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000039E1E1 WAC 21572407 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A WAC 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 WAC 21572407 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 WAC 21572407 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 WAC 21572407 22012620 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C WAC 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F WAC 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 WAC 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000411752 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 WAC 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 WAC 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001270D3 WAC 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDE70 WAC 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000004BACE WAC 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075D15B WAC 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001C770D WAC 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000060AABB WAC 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000009A9A2 WAC 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000020579D WAC 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00003AA845 WAC 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000042619A WAC 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001B968D WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004ACAAA WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC WAC 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 WAC 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000319E1 WAC 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00002FF522 WAC 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005E6F45 WAC 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000272039 WAC 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RNF40 WAC 25348397 N/A physical interaction ComPPI
VCP WAC 25348397 N/A physical interaction ComPPI
CRKL WAC 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TPM2 WAC 25348397 N/A physical interaction ComPPI
NFE2L2 WAC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TLN1 WAC 25348397 N/A physical interaction ComPPI
NDE1 WAC 25348397 N/A physical interaction ComPPI
EWSR1 WAC 25348397 N/A physical interaction ComPPI
PKM WAC 25348397 N/A protein kinase assay ComPPI
SYTL5 WAC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRAF1 WAC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ZDHHC17 WAC 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HTT WAC 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
POLR2A WAC 25348397 N/A physical interaction ComPPI
UBE2A WAC 25348397 N/A physical interaction ComPPI
CDK8 WAC 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VCPIP1 WAC 25348397 N/A physical interaction ComPPI
KLC3 WAC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRAF3IP1 WAC 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX1 WAC 25348397 N/A physical interaction ComPPI
KRT15 WAC 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
WAC APP 25348397 N/A physical interaction ComPPI
WAC AKAP9 25348397 N/A physical interaction ComPPI
WAC MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
WAC SIRT6 25348397 N/A physical interaction ComPPI
WAC SLAIN2 25348397 N/A physical interaction ComPPI
RNF20 WAC 25348397 N/A physical interaction ComPPI
GOLGB1 WAC 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B1B21 WAC 27087310 direct interaction,inhibition N/A NPInter

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