GENE:DNPEP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DNPEP |
| FullNmae | aspartyl aminopeptidase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2981 |
| EnsembleID | ENSG00000123992 |
| Uniprot | Q9ULA0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DNPEP | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DNPEP | GO:0004177,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0008237,GO:0008270,GO:0042802,GO:0072562 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DNPEP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | DNPEP | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| ETS1 | DNPEP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | DNPEP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | DNPEP | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | DNPEP | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | DNPEP | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | DNPEP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000821E0 | DNPEP | 21576357 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
| URS00000821E0 | DNPEP | 21576357 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS0000008A99 | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000221168 | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000512C88 | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003380CC | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CC20C | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005651EE | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002D349B | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003575B | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000259AE4 | DNPEP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SAT1 | DNPEP | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| TP53BP1 | DNPEP | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MCM2 | DNPEP | 25348397 | N/A | physical interaction | ComPPI |
| KRT31 | DNPEP | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MDFI | DNPEP | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| LGALS13 | DNPEP | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | ADAMTSL4 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| DNPEP | AGT | 12895663 14525934 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| DNPEP | KRT36 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DNPEP | KRT82 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DNPEP | DBNL | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DNPEP | TBC1D4 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | KIF4A | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DNPEP | NELFCD | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | PTPN12 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | TNS3 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | ASB3 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | DGCR6 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | MPP1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| DNPEP | LNX1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| DNPEP | TPI1 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | NF2 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | RAB11A | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | TAF15 | 25348397 | N/A | physical interaction | ComPPI |
| DNPEP | DNAJC9 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| DNPEP | HSDL2 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| DNPEP | XRCC4 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| DNPEP | KIF3A | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| DNPEP | PADI4 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| DNPEP | RBL1 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| DNPEP | SIRT4 | 24234451 25348397 25525879 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
