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GENE：VPS13C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VPS13C
FullNmae vacuolar protein sorting 13 homolog C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23594
EnsembleID ENSG00000129003
Uniprot Q709C8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VPS13C autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
VPS13C autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
VPS13C GO:0005737,GO:0005741,GO:0005764,GO:0005765,GO:0005770,GO:0005789,GO:0005811,GO:0005829,GO:0006623,GO:0006869,GO:0006895,GO:0007005,GO:0007005,GO:0019898,GO:0031902,GO:0032127,GO:0032868,GO:0045053,GO:0070062,GO:1905090

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR VPS13C 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 VPS13C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 VPS13C 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 VPS13C 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 VPS13C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 VPS13C 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 VPS13C 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 VPS13C 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000A939F VPS13C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 VPS13C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 VPS13C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F VPS13C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 VPS13C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 VPS13C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 VPS13C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 VPS13C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA VPS13C 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
VAPA VPS13C 25348397 N/A physical interaction ComPPI
HNRNPL VPS13C 25348397 N/A physical interaction ComPPI
RAB1A VPS13C 25348397 N/A physical interaction ComPPI
DNAJC7 VPS13C 25348397 N/A physical interaction ComPPI
VAPB VPS13C 25348397 N/A physical interaction ComPPI
RAB9A VPS13C 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ESR2 VPS13C 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
ARPC5 VPS13C 25348397 N/A physical interaction ComPPI
FAF2 VPS13C 25348397 N/A physical interaction ComPPI
RAB30 VPS13C 25348397 N/A physical interaction ComPPI
RNF19B VPS13C 25348397 N/A physical interaction ComPPI
HNRNPK VPS13C 24234451 30021884 physical association cross-linking study IntAct
HSP90B1 VPS13C 24234451 30021884 physical association cross-linking study IntAct
HNRNPA2B1 VPS13C 24234451 30021884 physical association cross-linking study IntAct

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