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GENE：ATP6V0A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6V0A2
FullNmae ATPase H+ transporting V0 subunit a2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18481
EnsembleID ENSG00000185344
Uniprot Q9Y487

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6V0A2 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
ATP6V0A2 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
ATP6V0A2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V0A2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V0A2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V0A2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP6V0A2 GO:0000139,GO:0000220,GO:0001669,GO:0005515,GO:0005765,GO:0005886,GO:0005886,GO:0005925,GO:0006879,GO:0006955,GO:0007035,GO:0010008,GO:0016241,GO:0016471,GO:0030670,GO:0033176,GO:0036295,GO:0043231,GO:0046961,GO:0048471,GO:0051117,GO:0061795,GO:1902495,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6V0A2 hsa:23545 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa04142 Lysosome - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa04966 Collecting duct acid secretion - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa05152 Tuberculosis - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6V0A2 hsa:23545 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ATP6V0A2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ATP6V0A2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ATP6V0A2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATP6V0A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP6V0A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATP6V0A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP6V0A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP6V0A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ATP6V0A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TEAD1 ATP6V0A2 15878913 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000075D15B ATP6V0A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 ATP6V0A2 23592263 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000527B00 ATP6V0A2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 ATP6V0A2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 ATP6V0A2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 ATP6V0A2 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000058C0AB ATP6V0A2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075A9CF ATP6V0A2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E ATP6V0A2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A ATP6V0A2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000045DBD ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D4175 ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000047A67D ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000209F04 ATP6V0A2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HOXB5 ATP6V0A2 25348397 N/A physical interaction ComPPI
RPS15 ATP6V0A2 25348397 N/A physical interaction ComPPI
ATP6V0C ATP6V0A2 25348397 N/A physical interaction ComPPI
CD4 ATP6V0A2 25348397 N/A physical interaction ComPPI
CYTH2 ATP6V0A2 14525934 16415858 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ATP6AP2 ATP6V0A2 25348397 N/A physical interaction ComPPI
LGALS8 ATP6V0A2 25348397 N/A physical interaction ComPPI
PTRH2 ATP6V0A2 25348397 N/A physical interaction ComPPI
BCAM ATP6V0A2 25348397 N/A physical interaction ComPPI
ELAVL1 ATP6V0A2 25348397 N/A physical interaction ComPPI
AKT1 ATP6V0A2 25348397 N/A physical interaction ComPPI
MARCKSL1 ATP6V0A2 25348397 N/A physical interaction ComPPI
GNAI1 ATP6V0A2 25348397 N/A physical interaction ComPPI
RPS2 ATP6V0A2 25348397 N/A physical interaction ComPPI
HLA-DQA1 ATP6V0A2 25348397 N/A physical interaction ComPPI
MTUS2 ATP6V0A2 25348397 N/A physical interaction ComPPI
SLC25A3 ATP6V0A2 25348397 N/A physical interaction ComPPI
ATP6AP1 ATP6V0A2 25348397 N/A physical interaction ComPPI
ATP6V0A2 MUC1 25348397 N/A physical interaction ComPPI
ATP6V0A2 MCAM 25348397 N/A physical interaction ComPPI
ATP6V0A2 ZNRF2 25348397 N/A physical interaction ComPPI
ATP6V0A2 CCDC115 25348397 N/A physical interaction ComPPI
ATP6V0A2 ATP6V0A1 25348397 N/A physical interaction ComPPI
ATP6V0A2 ANKLE2 25348397 N/A physical interaction ComPPI
ATP6V0A2 ANXA6 25348397 N/A physical interaction ComPPI
ATP6V0A2 ATP5PB 25348397 N/A physical interaction ComPPI
ATP6V1B2 ATP6V0A2 25348397 N/A physical interaction ComPPI
ATP6V0A2 DRD2 24234451 28298427 physical association ubiquitin reconstruction IntAct

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