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GENE：ATG4C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATG4C
FullNmae autophagy related 4C cysteine peptidase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16040
EnsembleID ENSG00000125703
Uniprot Q96DT6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATG4C autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATG4C GO:0000045,GO:0004197,GO:0005515,GO:0005575,GO:0005737,GO:0006508,GO:0006914,GO:0008234,GO:0015031,GO:0019786,GO:0051697

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATG4C hsa:84938 path:hsa04136 Autophagy - other - Homo sapiens (human)
ATG4C hsa:84938 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ATG4C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ATG4C 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ATG4C 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ATG4C 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR1I2 ATG4C 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ATG4C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003AD231 ATG4C 22248718 22743998 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS00000EED18 ATG4C 25416803 26313360 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
ATG4C BECN1 25361965 interaction type N/A PTMCode2
BECN1 ATG4C 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
WASL ATG4C 25348397 N/A physical interaction ComPPI
PRKDC ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB3IL1 ATG4C 25348397 N/A physical interaction ComPPI
PSMC5 ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMC1A ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC4 ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD2 ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP11 ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC1 ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTLC1 ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTA2 ATG4C 25348397 N/A physical interaction ComPPI
PSMC2 ATG4C 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KLHL22 ATG4C 25348397 N/A physical interaction ComPPI
ATG4C ATG4C 20562859 24234451 physical association anti tag coimmunoprecipitation IntAct

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