Gene Information gene info

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GENE：NRBF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NRBF2
FullNmae nuclear receptor binding factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19692
EnsembleID ENSG00000148572
Uniprot Q96F24

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NRBF2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NRBF2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NRBF2 GO:0005515,GO:0005654,GO:0005737,GO:0005776,GO:0006914,GO:0006914,GO:0031410,GO:0034976

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NRBF2 hsa:29982 path:hsa04140 Autophagy - animal - Homo sapiens (human)
NRBF2 hsa:29982 path:hsa05010 Alzheimer disease - Homo sapiens (human)
NRBF2 hsa:29982 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
NRBF2 hsa:29982 path:hsa05016 Huntington disease - Homo sapiens (human)
NRBF2 hsa:29982 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
NRBF2 hsa:29982 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG NRBF2 20098747 23180781 physical association protein array InnateDB
NRBF2 POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 NRBF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NRBF2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 NRBF2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NRBF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 NRBF2 19088304 20371350 21572407 23446348 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS00001597DC NRBF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007F792 NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 NRBF2 20371350 21572407 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 NRBF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F NRBF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 NRBF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 NRBF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 NRBF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 NRBF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 NRBF2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 NRBF2 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PPARA NRBF2 25361965 interaction type N/A PTMCode2
NRBF2 PPARA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
C1ORF216 NRBF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKAA2 NRBF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RARA NRBF2 10786636 14525934 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
THRB NRBF2 10786636 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PPARA NRBF2 25348397 N/A two hybrid,physical interaction ComPPI
NRBF2 HNF4A 25348397 N/A two hybrid ComPPI
NRBF2 RXRA 10786636 14525934 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
NRBF2 IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
NRBF2 BECN1 20562859 24234451 24785657 24849286 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
NRBF2 ATG14 20562859 24234451 24785657 24849286 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
NRBF2 CPVL 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NRBF2 PA2G4 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NRBF2 PGK1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NRBF2 PIK3C3 20562859 24234451 24785657 24849286 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
NRBF2 CCDC183 25348397 N/A physical interaction ComPPI
NRBF2 PIK3R4 24234451 24785657 24849286 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NRBF2 CALCOCO2 25348397 N/A physical interaction ComPPI
NRBF2 TGFBRAP1 25348397 N/A physical interaction ComPPI
NRBF2 GALT 25348397 N/A physical interaction ComPPI
NRBF2 SOGA3 25348397 N/A physical interaction ComPPI
NRBF2 EWSR1 25348397 N/A physical interaction ComPPI
NRBF2 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NRBF2 CEP44 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NRBF2 FBF1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NRBF2 SASS6 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NRBF2 RHOU 25348397 N/A physical interaction ComPPI
NRBF2 SCOC 25348397 N/A physical interaction ComPPI
NRBF2 PMF1 25348397 N/A physical interaction ComPPI
NRBF2 ULK1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
NRBF2 CCNC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NRBF2 KDM1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NRBF2 CDC23 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDA1 NRBF2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
NRBF2 NRBF2 20562859 24234451 physical association anti tag coimmunoprecipitation IntAct
IKBKG NRBF2 20098747 27898060 N/A N/A OmniPath

Visualization










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