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GENE：PIP4K2C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PIP4K2C
FullNmae phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23786
EnsembleID ENSG00000166908
Uniprot Q8TBX8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PIP4K2C autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PIP4K2C autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PIP4K2C GO:0005515,GO:0005524,GO:0005654,GO:0005776,GO:0005783,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0010506,GO:0016308,GO:0016308,GO:0016309,GO:0016310,GO:0042802,GO:0043229,GO:0046627,GO:0046854,GO:0070062,GO:1902635,GO:2000786

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PIP4K2C hsa:79837 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
PIP4K2C hsa:79837 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PIP4K2C hsa:79837 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)
PIP4K2C hsa:79837 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP PIP4K2C 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PIP4K2C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
E2F4 PIP4K2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PIP4K2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PIP4K2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PIP4K2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PIP4K2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 PIP4K2C 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D PIP4K2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001E0AEA PIP4K2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB PIP4K2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA PIP4K2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 PIP4K2C 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000243FF1 PIP4K2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PIP4K2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F PIP4K2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PIP4K2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 PIP4K2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PIP4K2C 22100165 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PIP4K2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00004A6E26 PIP4K2C 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 PIP4K2C 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B2B PIP4K2C 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 PIP4K2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B PIP4K2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004E02F2 PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000065FDF PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000020579D PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000025EABA PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000ECE9C PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000012930C PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B7450 PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC PIP4K2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000083D87 PIP4K2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000136174 PIP4K2C 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LZTS2 PIP4K2C 25348397 N/A physical interaction ComPPI
SKP1 PIP4K2C 25348397 N/A physical interaction ComPPI
NF2 PIP4K2C 25348397 N/A physical interaction ComPPI
BTK PIP4K2C 14525934 14614850 15046600 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TNFRSF1A PIP4K2C 25348397 N/A physical interaction ComPPI
CSNK2A1 PIP4K2C 25348397 N/A physical interaction ComPPI
ZRANB2 PIP4K2C 25348397 N/A physical interaction ComPPI
CSNK2A2 PIP4K2C 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EPB41L3 PIP4K2C 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1AN PIP4K2C 25348397 N/A physical interaction ComPPI
PJA1 PIP4K2C 25348397 N/A physical interaction ComPPI
GSPT2 PIP4K2C 25348397 N/A physical interaction ComPPI
EAF1 PIP4K2C 25348397 N/A physical interaction ComPPI
ELAVL1 PIP4K2C 25348397 N/A physical interaction ComPPI
BRAF PIP4K2C 25348397 N/A physical interaction ComPPI
TNFRSF19 PIP4K2C 25348397 N/A physical interaction ComPPI
CSNK2B PIP4K2C 25348397 N/A physical interaction ComPPI
ARL6IP4 PIP4K2C 25348397 N/A physical interaction ComPPI
MED4 PIP4K2C 25348397 N/A physical interaction ComPPI
HSD17B10 PIP4K2C 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
APBA3 PIP4K2C 25348397 N/A physical interaction ComPPI
GPBP1L1 PIP4K2C 25348397 N/A physical interaction ComPPI
PIP4K2A PIP4K2C 25348397 N/A physical interaction ComPPI
PIP4K2C APP 25348397 N/A physical interaction ComPPI
PIP4K2C FBXO25 25348397 N/A physical interaction ComPPI
PIP4K2C DDX23 25348397 N/A physical interaction ComPPI
PIP4K2C MTPN 25348397 N/A physical interaction ComPPI
PIP4K2C MYL9 25348397 N/A physical interaction ComPPI
PIP4K2C NCAPD3 25348397 N/A physical interaction ComPPI
PIP4K2C PRPF8 25348397 N/A physical interaction ComPPI
PIP4K2C ARHGAP22 25348397 N/A physical interaction ComPPI
PIP4K2C AHCYL2 25348397 N/A physical interaction ComPPI
PIP4K2C PRICKLE3 25348397 N/A physical interaction ComPPI
PIP4K2C TULP3 25348397 N/A physical interaction ComPPI
PIP4K2C ZNF428 25348397 N/A physical interaction ComPPI
PIP4K2C CAMKV 25348397 N/A physical interaction ComPPI
PIP4K2C POC1B 25348397 N/A physical interaction ComPPI
PIP4K2C SUN2 25348397 N/A physical interaction ComPPI
PIP4K2C DNAAF8 25348397 N/A physical interaction ComPPI
PIP4K2C PIP4K2C 18255255 24234451 physical association two hybrid,pull down IntAct

Visualization










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