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GENE：MOCS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MOCS2
FullNmae molybdenum cofactor synthesis 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7193
EnsembleID ENSG00000164172
Uniprot O96007|O96033

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MOCS2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MOCS2 GO:0005515,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0006777,GO:0016607,GO:0019008,GO:0030366,GO:0030366,GO:0032324

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MOCS2 hsa:4338 path:hsa00790 Folate biosynthesis - Homo sapiens (human)
MOCS2 hsa:4338 path:hsa01100 Metabolic pathways - Homo sapiens (human)
MOCS2 hsa:4338 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)
MOCS2 hsa:4338 path:hsa04122 Sulfur relay system - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 MOCS2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 MOCS2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MOCS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
ETS1 MOCS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MOCS2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MOCS2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MOCS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000027080C MOCS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F MOCS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 MOCS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 MOCS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED MOCS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 MOCS2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF MOCS2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RPL9 MOCS2 25348397 N/A two hybrid ComPPI
RPL9 MOCS2 14525934 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KRAS MOCS2 25348397 N/A physical interaction ComPPI
KRAS MOCS2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STK11 MOCS2 25348397 N/A physical interaction ComPPI
STK11 MOCS2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DYNLT1 MOCS2 25348397 N/A physical interaction ComPPI
DYNLT1 MOCS2 25348397 N/A physical interaction ComPPI
MOCS2 FANCM 25348397 N/A physical interaction ComPPI
FANCM MOCS2 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009BFE22 MOCS2 27087310 direct interaction,inhibition N/A NPInter

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