Gene Information gene info

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GENE：RRAGA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RRAGA
FullNmae Ras related GTP binding A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16963
EnsembleID ENSG00000155876
Uniprot Q7L523

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RRAGA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RRAGA autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RRAGA autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RRAGA GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005764,GO:0005765,GO:0005765,GO:0005829,GO:0006915,GO:0008104,GO:0009267,GO:0010507,GO:0010507,GO:0031625,GO:0031669,GO:0032008,GO:0033209,GO:0034198,GO:0035556,GO:0042593,GO:0042803,GO:0043495,GO:0046982,GO:0051219,GO:0061462,GO:0071230,GO:0072657,GO:1904263,GO:1904263,GO:1990131,GO:1990877

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RRAGA hsa:10670 path:hsa04140 Autophagy - animal - Homo sapiens (human)
RRAGA hsa:10670 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
RRAGA hsa:10670 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RRAGA RPTOR 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RRAGA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 RRAGA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A RRAGA 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 RRAGA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RRAGA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RRAGA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 RRAGA 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EED18 RRAGA 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RRAGD RRAGA 25361965 interaction type N/A PTMCode2
RRAGA RRAGD 25361965 interaction type N/A PTMCode2
RRAGC RRAGA 25361965 interaction type N/A PTMCode2
RRAGA RRAGC 25361965 interaction type N/A PTMCode2
RRAGA RPTOR 25361965 interaction type N/A PTMCode2
RPTOR RRAGA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC73 RRAGA 25348397 N/A physical interaction ComPPI
TBC1D7 RRAGA 25348397 N/A physical interaction ComPPI
LAMTOR4 RRAGA 22980980 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
LAMTOR3 RRAGA 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
TSC2 RRAGA 24529380 25348397 25936802 27898060 N/A physical interaction ComPPI,OmniPath
TSC1 RRAGA 25348397 N/A physical interaction ComPPI
RAB9A RRAGA 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DYNLT1 RRAGA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NPC2 RRAGA 25348397 N/A physical interaction ComPPI
LAMTOR2 RRAGA 20381137 22980980 24234451 25348397 25561175 25567906 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPTOR RRAGA 24234451 25348397 25561175 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGC RRAGA 11073942 14525934 16189514 20381137 22424946 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
RRAGB RRAGA 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
RRAGD RRAGA 11073942 22424946 24234451 25348397 25561175 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
RRAGA NOL8 14525934 14660641 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RRAGA LAMTOR1 22980980 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGA IL7R 25348397 N/A physical interaction ComPPI
RRAGA STAU1 25348397 N/A physical interaction ComPPI
RRAGA CTU2 25348397 N/A physical interaction ComPPI
RRAGA PPP1R1A 25348397 N/A physical interaction ComPPI
RRAGA SLC38A9 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGA MIOS 25348397 N/A physical interaction ComPPI
RRAGA DEPDC5 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
RRAGA RNF152 25348397 N/A physical interaction ComPPI
RRAGA NPRL2 25348397 N/A physical interaction ComPPI
RRAGA NPRL3 25348397 N/A physical interaction ComPPI
RRAGA LAMTOR5 22980980 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
RRAGA RRAGA 11073942 14525934 N/A experimental interaction detection,two hybrid HPRD
RRAGA RPTOR 18497260 21816923 23184942 24337580 26186194 27898060 inhibition N/A OmniPath
RPTOR RRAGA 18497260 21816923 23184942 24337580 26186194 27898060 N/A N/A OmniPath

Visualization










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