Gene Information gene info

GENE:RRAGC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RRAGC
FullNmae Ras related GTP binding C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19902
EnsembleID ENSG00000116954
Uniprot Q9HB90

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RRAGC autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RRAGC autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RRAGC autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RRAGC GO:0000287,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005525,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005764,GO:0005765,GO:0005829,GO:0006351,GO:0006915,GO:0007264,GO:0008104,GO:0008380,GO:0009267,GO:0010507,GO:0019003,GO:0019003,GO:0031669,GO:0032006,GO:0034198,GO:0043200,GO:0043231,GO:0043495,GO:0046982,GO:0051020,GO:0060090,GO:0061462,GO:0071230,GO:0072657,GO:0140767,GO:1903432,GO:1904263,GO:1904263,GO:1990131,GO:1990877

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RRAGC hsa:64121 path:hsa04140 Autophagy - animal - Homo sapiens (human)
RRAGC hsa:64121 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
RRAGC hsa:64121 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RPTOR RRAGC 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB
MTOR RRAGC 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RRAGC 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 RRAGC 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RRAGC 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RRAGC 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RRAGC 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RRAGC 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 RRAGC 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 RRAGC 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D RRAGC 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS0000076995 RRAGC 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 RRAGC 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB RRAGC 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS00000B7E30 RRAGC 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS000028DE3F RRAGC 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS00003003B4 RRAGC 21572407 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004407DC RRAGC 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 RRAGC 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF RRAGC 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF RRAGC 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 RRAGC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC RRAGC 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000045DBD RRAGC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E RRAGC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 RRAGC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D RRAGC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 RRAGC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 RRAGC 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B RRAGC 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000277201 RRAGC 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000202460 RRAGC 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RRAGC RRAGA 25361965 interaction type N/A PTMCode2
RRAGA RRAGC 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LGALS3 RRAGC 25348397 N/A physical interaction ComPPI
TBC1D7 RRAGC 25348397 N/A physical interaction ComPPI
TRAF6 RRAGC 25348397 N/A physical interaction ComPPI
LAMTOR4 RRAGC 22980980 24234451 25348397 25561175 association affinity chromatography technology,anti tag coimmunoprecipitation ComPPI,IntAct
LGALS9C RRAGC 25348397 N/A physical interaction ComPPI
LAMTOR3 RRAGC 20381137 22980980 24234451 25348397 25561175 association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SQSTM1 RRAGC 25348397 N/A physical interaction ComPPI
TSC2 RRAGC 25348397 N/A physical interaction ComPPI
TSC1 RRAGC 25348397 N/A physical interaction ComPPI
LGALS8 RRAGC 25348397 N/A physical interaction ComPPI
RAB9A RRAGC 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MPP3 RRAGC 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MTOR RRAGC 24234451 25348397 25446900 physical association physical interaction,proximity ligation assay ComPPI,IntAct
ATP6V1A RRAGC 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
LAMTOR2 RRAGC 20381137 22980980 24234451 25348397 25561175 25567906 association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPTOR RRAGC 24234451 25348397 25446900 25561175 25567906 association,physical association anti tag coimmunoprecipitation,physical interaction,proximity ligation assay ComPPI,IntAct
RRAGC RRAGB 11073942 14525934 20381137 22424946 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RRAGC RRAGA 11073942 14525934 16189514 20381137 22424946 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
RRAGC NOL8 14525934 14660641 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RRAGC ATXN1L 25348397 N/A physical interaction ComPPI
RRAGC LAMTOR1 20381137 22424946 22980980 24234451 25348397 25561175 25567906 colocalization,association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
RRAGC WNT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RRAGC RRAGD 25348397 N/A physical interaction ComPPI
RRAGC LGALS9 25348397 N/A physical interaction ComPPI
RRAGC MIOS 25348397 N/A physical interaction ComPPI
RRAGC WDR24 25348397 N/A physical interaction ComPPI
RRAGC DEPDC5 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
RRAGC FPR2 25348397 N/A physical interaction ComPPI
RRAGC SLC38A9 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGC LAMTOR5 22980980 24234451 25348397 25561175 association affinity chromatography technology,anti tag coimmunoprecipitation ComPPI,IntAct
ATP6V1B2 RRAGC 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
RRAGC RRAGC 11073942 14525934 14660641 N/A experimental interaction detection HPRD
RPTOR RRAGC 18497260 21816923 21981924 24337580 25446900 27898060 N/A N/A OmniPath
RRAGC RPTOR 18497260 20006481 21816923 21981924 24337580 25446900 27898060 inhibition,stimulant N/A OmniPath
RRAGC MTOR 18497260 21981924 24337580 25446900 27898060 inhibition N/A OmniPath

Visualization