GENE:TBC1D5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TBC1D5 |
| FullNmae | TBC1 domain family member 5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:19166 |
| EnsembleID | ENSG00000131374 |
| Uniprot | Q92609 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TBC1D5 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TBC1D5 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TBC1D5 | GO:0002092,GO:0005096,GO:0005515,GO:0005776,GO:0005794,GO:0005829,GO:0006914,GO:0010008,GO:0015031,GO:0016236,GO:0030904,GO:0035612,GO:0042147,GO:0042594,GO:0043231,GO:0044877,GO:0090630,GO:1905394 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TBC1D5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | TBC1D5 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | TBC1D5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TBC1D5 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | TBC1D5 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | TBC1D5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000ED600 | TBC1D5 | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000077AED | TBC1D5 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000EF0B | TBC1D5 | 19536157 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0BB4 | TBC1D5 | 19536157 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | TBC1D5 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005E1A16 | TBC1D5 | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CF1D2 | TBC1D5 | 19536157 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EIF1AD | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| ZBTB25 | TBC1D5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| GABARAPL2 | TBC1D5 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ATXN1 | TBC1D5 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,pull down,physical interaction,two hybrid array,two hybrid | ComPPI,HPRD,IntAct |
| MAP1LC3B | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAB | TBC1D5 | 24234451 24255178 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| UBC | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRR | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| AP2A1 | TBC1D5 | 24234451 24603492 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| MAP1LC3A | TBC1D5 | 25348397 | N/A | physical interaction | ComPPI |
| RAB9A | TBC1D5 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| AP2M1 | TBC1D5 | 14525934 16189514 24234451 24603492 25348397 | physical association | two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| VPS35 | TBC1D5 | 20923837 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ULK1 | TBC1D5 | 24234451 24603492 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| TGOLN2 | TBC1D5 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| VPS29 | TBC1D5 | 19531583 20923837 22354992 24234451 24603492 25348397 25416956 27898060 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct,OmniPath |
| TBC1D5 | GABARAPL1 | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TBC1D5 | VPS26A | 20923837 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TBC1D5 | VPS26B | 20923837 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TBC1D5 | WASHC2A | 25348397 | N/A | physical interaction | ComPPI |
| TBC1D5 | TMEM17 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| TBC1D5 | ATG9A | 24234451 24603492 25348397 | colocalization,association | anti tag coimmunoprecipitation,fluorescence microscopy | ComPPI,IntAct |
| TBC1D5 | ATG13 | 24234451 24603492 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| TBC1D5 | ZFYVE1 | 24234451 24603492 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| TBC1D5 | WASHC5 | 20923837 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| TBC1D5 | CHIA | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TBC1D5 | FBXL7 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCAR1 | TBC1D5 | 24234451 30021884 | physical association | cross-linking study | IntAct |
