GENE：ATP6V1H
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ATP6V1H |
| FullNmae | ATPase H+ transporting V1 subunit H |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18303 |
| EnsembleID | ENSG00000047249 |
| Uniprot | Q9UI12 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ATP6V1H | lysosomal_cd | 36341760 | 220 lysosome-dependent cell death genes. | retulator signature |
| ATP6V1H | lysosomal_cd | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| ATP6V1H | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ATP6V1H | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ATP6V1H | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ATP6V1H | GO:0000139,GO:0000221,GO:0000221,GO:0005515,GO:0005765,GO:0005765,GO:0005829,GO:0005886,GO:0005886,GO:0006897,GO:0007035,GO:0007042,GO:0010008,GO:0016020,GO:0016241,GO:0016887,GO:0030234,GO:0030665,GO:0033176,GO:0046961,GO:0048388,GO:0051452,GO:0061795,GO:0070062,GO:0097401,GO:0098850,GO:1902495,GO:1902600 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ATP6V1H | hsa:51606 | path:hsa00190 | Oxidative phosphorylation - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa04142 | Lysosome - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa04145 | Phagosome - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa04150 | mTOR signaling pathway - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa04721 | Synaptic vesicle cycle - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa05110 | Vibrio cholerae infection - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa05120 | Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa05152 | Tuberculosis - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
| ATP6V1H | hsa:51606 | path:hsa05323 | Rheumatoid arthritis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ATP6V1H | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ATP6V1H | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | ATP6V1H | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | ATP6V1H | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ATP6V1H | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SPATA2 | ATP6V1H | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CDC42 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| SORBS3 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| NF2 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| UBE2N | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| PROCR | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| MYC | ATP6V1H | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| MAPK6 | ATP6V1H | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| SOX9 | ATP6V1H | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| RAB2A | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| VDAC2 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| EGFR | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPUL1 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| CDKN2B | ATP6V1H | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBQLN1 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| STMN1 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| TANK | ATP6V1H | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| EEF2 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| PPP1R12C | ATP6V1H | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| FAF2 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| RMDN3 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| MED20 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| ZFAND5 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| VDAC3 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| ETHE1 | ATP6V1H | 14525934 16169070 24234451 25348397 | physical association | two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PTP4A3 | ATP6V1H | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| MAS1 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| ATP5PB | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1H | ZMPSTE24 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1H | ABCC1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1H | USP3 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1H | GOLT1B | 25348397 | N/A | physical interaction | ComPPI |
| MRPL1 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B2 | ATP6V1H | 25348397 | N/A | physical interaction | ComPPI |