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GENE：PARP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PARP1
FullNmae poly(ADP-ribose) polymerase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:270
EnsembleID ENSG00000143799
Uniprot P09874

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PARP1 parthanatos 40436476 In the MCAO group, there was an excessive activation of PARP1, which triggered parthanatos. retulator signature
PARP1 necroptosis 37066722 Dexmedetomidine may target PARP1 to promote necroptosis and then affect NSCLC. retulator signature
PARP1 necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
PARP1 apoptosis 38940933 These data suggest that the combination of donafenib and a PARP1 inhibitor results in more significant DNA damage in cells and promotes cell apoptosis. retulator signature
PARP1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PARP1 GO:0000122,GO:0000122,GO:0000723,GO:0000781,GO:0000785,GO:0003677,GO:0003682,GO:0003684,GO:0003723,GO:0003950,GO:0003950,GO:0003950,GO:0003950,GO:0005515,GO:0005634,GO:0005635,GO:0005654,GO:0005654,GO:0005667,GO:0005730,GO:0005730,GO:0005739,GO:0005829,GO:0006281,GO:0006281,GO:0006302,GO:0006302,GO:0006302,GO:0006366,GO:0006915,GO:0006974,GO:0006974,GO:0007005,GO:0007179,GO:0008270,GO:0010332,GO:0010613,GO:0016020,GO:0016051,GO:0016540,GO:0016604,GO:0016779,GO:0019899,GO:0019901,GO:0023019,GO:0030225,GO:0030331,GO:0030592,GO:0031491,GO:0031625,GO:0032042,GO:0032786,GO:0032869,GO:0032880,GO:0032991,GO:0032993,GO:0033148,GO:0034244,GO:0034599,GO:0034644,GO:0035861,GO:0036211,GO:0042802,GO:0042803,GO:0042826,GO:0043123,GO:0043504,GO:0043596,GO:0044030,GO:0045087,GO:0045188,GO:0045824,GO:0045824,GO:0045892,GO:0045944,GO:0046697,GO:0050790,GO:0051287,GO:0051901,GO:0060391,GO:0060545,GO:0061629,GO:0070212,GO:0070212,GO:0070213,GO:0070412,GO:0071168,GO:0071294,GO:0071932,GO:0090734,GO:0090734,GO:0140294,GO:0140805,GO:0140806,GO:0140807,GO:0140808,GO:0140815,GO:0140816,GO:0140817,GO:0140822,GO:1900182,GO:1903376,GO:1903518,GO:1904044,GO:1904178,GO:1904357,GO:1904646,GO:1904762,GO:1905051,GO:1905168,GO:1990090,GO:1990404,GO:1990404,GO:1990966,GO:2001170

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PARP1 hsa:142 path:hsa03410 Base excision repair - Homo sapiens (human)
PARP1 hsa:142 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
PARP1 hsa:142 path:hsa04210 Apoptosis - Homo sapiens (human)
PARP1 hsa:142 path:hsa04217 Necroptosis - Homo sapiens (human)
PARP1 hsa:142 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BRCA1 PARP1 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 26192618 9721205 interaction type N/A ACSN
PARP1 MRE11 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 26192618 9721205 interaction type N/A ACSN
PARP1 PARP2 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 18835851 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21037379 21060331 21076181 21270334 21337561 21376743 21818122 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 26192618 9721205 association N/A ACSN
PARP1 RAD50 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 26192618 9721205 interaction type N/A ACSN
PARP1 XRCC1 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 26192618 8264637 8978692 interaction type N/A ACSN
PCNA PARP1 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506 26192618 interaction type N/A ACSN
PARP1 POLB 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 26192618 8264637 8978692 interaction type N/A ACSN
PARP1 POLE 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506 26192618 interaction type N/A ACSN
PARP1 PARP3 14726013 15703371 16697054 17088286 17116881 18077224 19208614 19364882 196269035 19847258 20603072 21211721 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23178593 23562323 23568489 24050180 24210699 24684389 24976506 26192618 association N/A ACSN
PARP1 WRN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15211575 15385537 15385968 15498778 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19654615 19748837 19847258 19892829 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 26192618 8264637 8978692 interaction type N/A ACSN
ATR PARP1 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 26192618 9488723 9858600 interaction type N/A ACSN
ATM PARP1 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 26192618 9168117 9858600 interaction type N/A ACSN
PARG PARP1 196269035 22469522 22713970 23110147 24684389 26192618 interaction type N/A ACSN
PARP1 SNAI1 14726013 15211575 15498778 15703371 16697054 17088286 17116881 17965729 18584027 18809224 19208614 19362533 19364882 19654615 19847258 19892829 20064462 20603072 21270334 21376743 21577210 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24089143 24095737 24210699 24684389 24976506 26192618 interaction type N/A ACSN
CDK5 PARP1 12556884 16332722 16858402 17303408 19151707 20724832 21727086 21922195 23589330 23850759 26192618 interaction type N/A ACSN
CTNNB1 PARP1 16230076 23180781 physical association anti tag coimmunoprecipitation InnateDB
AR PARP1 17011549 23180781 physical association anti tag coimmunoprecipitation InnateDB
CASP7 PARP1 23180781 9875225 cleavage reaction enzymatic study,protease assay InnateDB
CASP3 PARP1 23180781 9875225 cleavage reaction enzymatic study,protease assay InnateDB
RELA PARP1 16799643 23180781 physical association anti tag coimmunoprecipitation InnateDB
CXCL1 PARP1 16799643 23180781 physical association anti tag coimmunoprecipitation InnateDB
GZMB PARP1 12745270 16798735 23180781 protein cleavage protease assay InnateDB
GZMM PARP1 16818775 23180781 protein cleavage protease assay InnateDB
NFAT5 PARP1 17148781 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDK2 PARP1 21319273 23180781 physical association anti tag coimmunoprecipitation InnateDB
MECOM PARP1 23180781 23858473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PARP1 18971253 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
E2F4 PARP1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PARP1 10435618 11973649 18971253 20019798 24448423 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC PARP1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PARP1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PARP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EP300 PARP1 17065349 trascriptional regulation,stimulation inferred by curator TFlink
YY1 PARP1 9367892 trascriptional regulation,stimulation inferred by curator TFlink
MYB PARP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A PARP1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B7E30 PARP1 23757351 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000ED600 PARP1 20584986 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS000009262D PARP1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00000FC8EB PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000036AFF1 PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003FD55 PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002152A8 PARP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000B7E30 PARP1 23757351 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000019D79B PARP1 23754151 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS000031602A PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE PARP1 20371350 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A PARP1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 PARP1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 PARP1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 PARP1 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000037E170 PARP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 PARP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 PARP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 PARP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000048F59D PARP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCDA3 PARP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A PARP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E2232 PARP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED PARP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF PARP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 PARP1 25416803 28281524 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 PARP1 25416803 27871924 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA2 PARP1 22135298 phosphorylation N/A PhosphoSite
MAPK1 PARP1 22135298 phosphorylation N/A PhosphoSite
MET PARP1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PIAS2 PARP1 25348397 N/A anti tag coimmunoprecipitation ComPPI
LGALS3 PARP1 25348397 N/A physical interaction ComPPI
UBE2I PARP1 15561718 19596686 23871147 25348397 27898060 9197546 N/A physical interaction ComPPI,OmniPath
CDC5L PARP1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DAXX PARP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AIMP2 PARP1 25348397 N/A physical interaction ComPPI
DDX21 PARP1 25348397 N/A physical interaction ComPPI
HSPA2 PARP1 25348397 N/A physical interaction ComPPI
BAG3 PARP1 25348397 N/A physical interaction ComPPI
NPM1 PARP1 14525934 25348397 9642267 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RARA PARP1 14525934 15808511 24234451 25303530 25348397 association experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
PCNA PARP1 12930846 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CDKN1A PARP1 12930846 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
POLB PARP1 25348397 N/A physical interaction ComPPI
TUBB PARP1 25348397 N/A physical interaction ComPPI
TRAF6 PARP1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ZBTB9 PARP1 25348397 N/A physical interaction ComPPI
LMNA PARP1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
BMI1 PARP1 25348397 N/A physical interaction ComPPI
H2BC4 PARP1 25348397 N/A physical interaction ComPPI
KEAP1 PARP1 25348397 N/A physical interaction ComPPI
SNAI1 PARP1 21577210 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,confocal microscopy ComPPI,IntAct
CTSG PARP1 11536009 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
EXOSC1 PARP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
APLF PARP1 17396150 18172500 20098424 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,enzymatic study ComPPI,IntAct
CETN2 PARP1 25348397 N/A physical interaction ComPPI
NMNAT1 PARP1 17360427 24234451 25348397 N/A filter binding,physical interaction ComPPI,IntAct
SWAP70 PARP1 14525934 25348397 9642267 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
H4C1 PARP1 25348397 N/A physical interaction ComPPI
NF2 PARP1 25348397 N/A physical interaction ComPPI
TXNIP PARP1 25348397 N/A physical interaction ComPPI
MAPK1 PARP1 16627622 24234451 25348397 phosphorylation reaction phosphorylation reaction,protein kinase assay ComPPI,IntAct
RPL10 PARP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SP1 PARP1 17961220 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CD81 PARP1 24234451 25348397 26212323 association anti bait coimmunoprecipitation ComPPI,IntAct
NOTCH1 PARP1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NFATC1 PARP1 18078995 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SPI1 PARP1 21575865 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ETV1 PARP1 21575865 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CASP3 PARP1 17167422 24234451 25348397 7596430 protein cleavage physical interaction,protease assay,protein cleavage ComPPI,IntAct
PRKDC PARP1 14525934 20085707 21575865 24234451 25348397 9398855 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
MAPK3 PARP1 16627622 24234451 25348397 phosphorylation reaction phosphorylation reaction,protein kinase assay ComPPI,IntAct
PPP1R15A PARP1 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
JUN PARP1 24234451 25348397 25609649 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CREBBP PARP1 25348397 N/A physical interaction ComPPI
HMGA1 PARP1 25348397 N/A physical interaction ComPPI
SUMO1 PARP1 19779455 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EP300 PARP1 25348397 N/A physical interaction ComPPI
HIF1A PARP1 25348397 N/A physical interaction ComPPI
COPS5 PARP1 25348397 N/A physical interaction ComPPI
HDAC3 PARP1 25348397 N/A physical interaction ComPPI
KAT2B PARP1 25348397 N/A physical interaction ComPPI
PNKP PARP1 25348397 N/A physical interaction ComPPI
POLA1 PARP1 14525934 25348397 9518481 9563011 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CTSB PARP1 25348397 N/A physical interaction ComPPI
SPP1 PARP1 25348397 N/A physical interaction ComPPI
MAFG PARP1 25348397 N/A physical interaction ComPPI
MAFF PARP1 25348397 N/A physical interaction ComPPI
MYBL2 PARP1 10744766 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
THRA PARP1 25348397 N/A physical interaction ComPPI
THRB PARP1 25348397 N/A physical interaction ComPPI
MED1 PARP1 25348397 N/A physical interaction ComPPI
MED24 PARP1 25348397 N/A physical interaction ComPPI
PRKAA1 PARP1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC PARP1 18041763 19779455 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct,OmniPath
NTRK1 PARP1 25348397 N/A physical interaction ComPPI
PRMT1 PARP1 25348397 N/A physical interaction ComPPI
RNH1 PARP1 21276451 24234451 25348397 27898060 colocalization cosedimentation,cosedimentation in solution ComPPI,IntAct,OmniPath
TCF7L2 PARP1 17283121 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CASP1 PARP1 14525934 25348397 7642516 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PARP1 RPS3A 11790116 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PARP1 XRCC1 14500814 14525934 15044383 15555565 18971944 24234451 24778456 25348397 9584196 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
PARP1 ZNF423 14525934 14623329 22863007 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
PARP1 WRN 14525934 14596914 14734561 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction,in vivo ComPPI,HPRD,IntAct
PARP1 NCOA6 12519782 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PARP1 APTX 14525934 15044383 15555565 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
PARP1 XRCC5 14525934 14734561 17283121 20085707 21575865 21679440 24234451 25348397 adp ribosylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,enzymatic study,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
PARP1 PARP2 12217960 14525934 19629035 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PARP1 RBM14 11443112 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PARP1 SREK1 14525934 14559993 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PARP1 NEDD8 14525934 16620772 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PARP1 MED6 14525934 15808511 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PARP1 CENPA 12011073 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PARP1 CENPB 12011073 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PARP1 ERCC6 14525934 16107709 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PARP1 RELA 11590148 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD
PARP1 PARP3 25348397 N/A physical interaction,in vivo ComPPI
PARP1 LIG3 12897160 14525934 24234451 24778456 25348397 association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PARP1 XRCC6 14525934 14734561 17283121 24234451 25348397 adp ribosylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction,enzymatic study,in vivo ComPPI,HPRD,IntAct
PARP1 E2F1 14525934 14627987 20133863 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PARP1 MACROH2A1 14525934 17158748 17322296 24234451 25306110 25348397 25417162 27898060 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
PARP1 BCL2 11790116 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PARP1 NFKB1 11590148 14525934 24234451 25348397 25609649 association experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
PARP1 POU2F1 25348397 27898060 9537509 N/A two hybrid,physical interaction,in vitro ComPPI,OmniPath
PARP1 TERF2IP 25348397 N/A physical interaction ComPPI
PARP1 TP53 12898523 14525934 14627987 15044383 24234451 25348397 9565608 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
PARP1 TAL1 25348397 N/A physical interaction ComPPI
PARP1 POLA2 25348397 N/A physical interaction ComPPI
PARP1 PTK2 25348397 N/A physical interaction ComPPI
PARP1 RRP1B 19710015 20926688 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PARP1 USP36 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP1 MEPCE 25348397 N/A physical interaction ComPPI
PARP1 TCEA2 25348397 N/A physical interaction ComPPI
PARP1 AIRE 25348397 N/A physical interaction ComPPI
PARP1 NIPSNAP2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP1 FOXO1 25348397 N/A physical interaction ComPPI
PARP1 NRF1 25348397 N/A physical interaction ComPPI
PARP1 H1-1 25348397 N/A physical interaction ComPPI
PARP1 PIAS4 19779455 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PARP1 IMMT 19762472 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PARP1 BANF1 25348397 N/A physical interaction ComPPI
PARP1 CHD1L 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction,atpase assay ComPPI
PARP1 SENP1 25348397 N/A physical interaction ComPPI
PARP1 SENP3 25348397 N/A physical interaction ComPPI
PARP1 TRIM29 25348397 N/A physical interaction ComPPI
PARP1 MYB 25348397 N/A physical interaction ComPPI
PARP1 SMARCA1 25348397 N/A physical interaction ComPPI
PARP1 ESR1 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
PARP1 TOP2B 25348397 N/A physical interaction ComPPI
PARP1 SUPT16H 25348397 N/A physical interaction ComPPI
PARP1 TRIM28 25348397 N/A physical interaction ComPPI
PARP1 NCAPD2 16543152 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PARP1 NCAPG 25348397 N/A physical interaction ComPPI
PARP1 H2AX 16377563 20000738 20085707 24234451 25348397 27728808 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
PARP1 BUB1B 16449973 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PARP1 GTF2F1 25348397 N/A physical interaction ComPPI
PARP1 MED14 25348397 N/A physical interaction ComPPI
PARP1 MED23 25348397 N/A physical interaction ComPPI
PARP1 MED17 25348397 N/A physical interaction ComPPI
PARP1 CDK8 25348397 N/A physical interaction ComPPI
PARP1 THRAP3 25348397 N/A physical interaction ComPPI
PARP1 HDAC1 25348397 N/A physical interaction ComPPI
PARP1 HDAC2 25348397 N/A physical interaction ComPPI
PARP1 CARM1 25348397 N/A physical interaction ComPPI
PARP1 H1-2 25348397 N/A physical interaction ComPPI
PARP1 ATM 25348397 N/A physical interaction ComPPI
PARP1 TOPORS 25348397 N/A physical interaction ComPPI
PARP1 HDAC9 25348397 N/A physical interaction ComPPI
PARP1 H2AC18 25348397 N/A physical interaction ComPPI
PARP1 H2BC1 25348397 N/A physical interaction ComPPI
PARP1 CTCF 14759373 19450526 20038529 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PARP1 RYK 25348397 N/A physical interaction ComPPI
PARP1 KLF8 21518760 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PARP1 USF1 19303849 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP1 HDAC5 25348397 N/A physical interaction ComPPI
PARP1 TOP1 15848144 24234451 25348397 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PARP1 VHL 25348397 N/A physical interaction ComPPI
PARP1 RNF146 25348397 N/A physical interaction ComPPI
PARP1 SMARCAD1 25348397 N/A physical interaction ComPPI
PARP1 HDGF 21907836 24234451 25348397 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PARP1 HES1 25348397 N/A physical interaction ComPPI
PARP1 CEBPA 16490787 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP1 ELAVL1 25348397 N/A physical interaction ComPPI
PARP1 CHFR 18172500 19182791 22337872 25348397 27898060 N/A physical interaction,enzymatic study ComPPI,OmniPath
PARP1 ERG 21575865 24234451 25348397 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
PARP1 CDK2 25348397 N/A physical interaction ComPPI
PARP1 CAND1 25348397 N/A physical interaction ComPPI
PARP1 ZBTB16 25348397 N/A physical interaction ComPPI
PARP1 PGR 25348397 N/A physical interaction ComPPI
PARP1 FMNL1 25348397 N/A physical interaction ComPPI
PARP1 GZMM 25348397 N/A physical interaction ComPPI
PARP1 FN1 25348397 N/A physical interaction ComPPI
PARP1 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PARP1 ITGA4 25348397 N/A physical interaction ComPPI
PARP1 CBX2 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PARP1 CBX4 25348397 N/A physical interaction ComPPI
PARP1 CTNNB1 25348397 N/A physical interaction ComPPI
PARP1 CASP7 25348397 N/A physical interaction ComPPI
PARP1 PAN2 25348397 N/A physical interaction ComPPI
PARP1 ERCC6 25348397 N/A physical interaction ComPPI
PARP1 CD86 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PARP1 BLM 25348397 N/A physical interaction ComPPI
PARP1 RPL19 25348397 N/A physical interaction ComPPI
PARP1 MAFK 25348397 N/A physical interaction ComPPI
PARP1 ABL1 25348397 N/A physical interaction ComPPI
PARP1 RPL35 25348397 N/A physical interaction ComPPI
PARP1 RPL27A 25348397 N/A physical interaction ComPPI
PARP1 PHB 25348397 N/A physical interaction ComPPI
PARP1 RPS8 25348397 N/A physical interaction ComPPI
PARP1 ATP5F1A 25348397 N/A physical interaction ComPPI
PARP1 DDX39A 25348397 N/A physical interaction ComPPI
PARP1 TUBB1 25348397 N/A physical interaction ComPPI
PARP1 POLG2 25348397 N/A physical interaction ComPPI
PARP1 PDLIM7 25348397 N/A physical interaction ComPPI
PARP1 RAD23A 25348397 N/A physical interaction ComPPI
PARP1 HNRNPH1 25348397 N/A physical interaction ComPPI
PARP1 NQO1 25348397 N/A physical interaction ComPPI
PARP1 RPA2 25348397 N/A physical interaction ComPPI
PARP1 RPA3 25348397 N/A physical interaction ComPPI
PARP1 UHRF1 25348397 N/A physical interaction ComPPI
PARP1 RIOK2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PARP1 PARP9 25348397 N/A physical interaction ComPPI
PARP1 DDB2 25348397 N/A physical interaction ComPPI
PARP1 IVNS1ABP 25348397 N/A physical interaction ComPPI
PARP1 DNMT1 24234451 25348397 27728808 colocalization,association,physical association anti bait coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
PARP1 HUWE1 25348397 N/A physical interaction ComPPI
PARP1 BANP 25348397 N/A physical interaction ComPPI
PARP1 SHMT2 25348397 N/A physical interaction ComPPI
PARP1 MOV10 25348397 N/A physical interaction ComPPI
PARP1 NXF1 25348397 N/A physical interaction ComPPI
PARP1 SIRT1 25348397 N/A physical interaction ComPPI
PARP1 CUL7 25348397 N/A physical interaction ComPPI
PARP1 OBSL1 25348397 N/A physical interaction ComPPI
PARP1 CCDC8 25348397 N/A physical interaction ComPPI
PARP1 CASP8 25348397 N/A physical interaction ComPPI
PARP1 MAST3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP1 WDR76 25348397 N/A physical interaction ComPPI
PARP1 RPA4 25348397 N/A physical interaction ComPPI
PARP1 RNF166 25348397 N/A physical interaction ComPPI
PARP1 KLF5 17283079 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PARP1 TCF3 25348397 N/A two hybrid,physical interaction,physical interaction ComPPI
PARP1 BLID 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PARP1 IL24 24234451 25348397 25640309 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PARP1 MTA3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PARP1 RASL10B 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PARP1 EWSR1 25348397 N/A physical interaction ComPPI
PARP1 UIMC1 25348397 N/A physical interaction ComPPI
PARP1 BRCA1 25348397 N/A physical interaction ComPPI
PARP1 ABRAXAS1 25348397 N/A physical interaction ComPPI
PARP1 BARD1 25348397 N/A physical interaction ComPPI
PARP1 MACROD1 25348397 N/A physical interaction ComPPI
PARP1 IKBKG 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
PARP1 UHRF2 25348397 N/A physical interaction ComPPI
PARP1 DTX3L 25348397 N/A physical interaction ComPPI
PARP1 RC3H1 25348397 N/A physical interaction ComPPI
PARP1 NFATC2 25348397 N/A physical interaction ComPPI
PARP1 HPF1 25348397 N/A physical interaction ComPPI
PARP1 H1-5 25348397 N/A physical interaction ComPPI
PARP1 H3-4 25348397 N/A physical interaction ComPPI
PARP1 HMGN1 25348397 N/A physical interaction ComPPI
PARP1 HMGN2 25348397 N/A physical interaction ComPPI
PARP1 HMGN4 25348397 N/A physical interaction ComPPI
PARP1 H2BC11 25348397 N/A physical interaction ComPPI
PARP1 H1-0 25348397 N/A physical interaction ComPPI
PARP1 EGFR 24234451 24780295 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP1 HIPK2 25348397 N/A physical interaction ComPPI
PARP1 HSPA1A 25348397 N/A physical interaction ComPPI
PARP1 HSPA1B 25348397 N/A physical interaction ComPPI
PARP1 STUB1 25348397 N/A physical interaction ComPPI
PARP1 CHD4 25348397 N/A physical interaction ComPPI
PARP1 DERL1 25348397 N/A physical interaction ComPPI
PARP1 ZNF746 25348397 N/A physical interaction ComPPI
PARP1 PPM1G 25348397 N/A physical interaction ComPPI
PARP1 XPC 25348397 N/A physical interaction ComPPI
PARP1 SSRP1 25348397 N/A physical interaction ComPPI
PARP1 NR3C1 25348397 N/A physical interaction ComPPI
PARP1 CYLD 25348397 N/A physical interaction ComPPI
PARP1 ECD 25348397 N/A physical interaction ComPPI
PARP1 YAP1 25348397 N/A physical interaction ComPPI
PARP1 MTF1 25348397 N/A physical interaction ComPPI
PARP1 CHD7 20130577 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP1 RECQL 23396353 24234451 25348397 27898060 adp ribosylation reaction,association,physical association anti bait coimmunoprecipitation,far western blotting,pull down,physical interaction,adp ribosylation reaction,tandem affinity purification,adp ribosylase assay ComPPI,IntAct,OmniPath
PARP1 YARS1 24234451 25348397 25533949 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PARP1 IKBKB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PARP1 NFKB2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PARP1 TRAF2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PARP1 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PARP1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PARP1 MAPK13 19135240 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 TOP2A 20085707 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 NBN 19629035 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 MRE11 19629035 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 SUMO2 19779455 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PARP1 RNF4 19779455 24234451 25348397 N/A pull down ComPPI,IntAct
PARP1 ETS1 21575865 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
PARP1 MEX3C 22863774 24234451 25348397 association pull down ComPPI,IntAct
PARP1 OARD1 23481255 24234451 25348397 enzymatic reaction,physical association anti tag coimmunoprecipitation,cross-linking study,enzymatic study ComPPI,IntAct
PARP1 PARG 23481255 24234451 25348397 enzymatic reaction enzymatic study ComPPI,IntAct
PARP1 YY1 23531880 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
PARP1 PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
PARP1 NFIC 24145797 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PARP1 INO80 24145797 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PARP1 EP400 24145797 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PARP1 DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
PARP1 DNMT3B 24234451 25348397 27728808 association anti bait coimmunoprecipitation ComPPI,IntAct
BUB3 PARP1 12011073 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RPA1 PARP1 25348397 N/A physical interaction ComPPI
HMGB1 PARP1 25348397 N/A physical interaction ComPPI
H3C1 PARP1 20080577 24234451 25348397 29568061 association physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
TAF13 PARP1 25348397 N/A physical interaction ComPPI
H3-3A PARP1 25348397 N/A physical interaction ComPPI
CETN1 PARP1 25348397 N/A physical interaction ComPPI
HOXB7 PARP1 25348397 N/A physical interaction ComPPI
RPL14 PARP1 25348397 N/A physical interaction ComPPI
LZTR1 PARP1 25348397 N/A physical interaction ComPPI
MED7 PARP1 25348397 N/A physical interaction ComPPI
SNRNP27 PARP1 25348397 N/A physical interaction ComPPI
THRSP PARP1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PARP1 PARP1 12519782 14525934 14734561 23481255 24234451 enzymatic reaction,adp ribosylation reaction experimental interaction detection,enzymatic study HPRD,IntAct
RXRA PARP1 10082530 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
PARP1 NCL 14525934 9642267 N/A experimental interaction detection HPRD
GZMB PARP1 14525934 9586635 N/A experimental interaction detection HPRD
TCF4 PARP1 14525934 17283121 N/A experimental interaction detection HPRD
BRCA2 PARP1 18990703 24234451 association,physical association pull down,chromatin immunoprecipitation assay,electrophoretic mobility supershift assay IntAct
PARP1 ISWI 18922045 24234451 N/A anti tag coimmunoprecipitation IntAct
METTL14 PARP1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
PARP1 SPTA1 24234451 30021884 physical association cross-linking study IntAct
PARP1 C9ORF43 24234451 30021884 physical association cross-linking study IntAct
PARP1 NUDCD3 24234451 30021884 physical association cross-linking study IntAct
H2BC9 PARP1 24234451 30021884 physical association cross-linking study IntAct
PARP1 LRRC31 24234451 30021884 physical association cross-linking study IntAct
PARP1 NADSYN1 24234451 30021884 physical association cross-linking study IntAct
PARP1 PPP2R2A 24234451 30021884 physical association cross-linking study IntAct
PARP1 HIVEP1 24234451 30021884 physical association cross-linking study IntAct
PARP1 MORC2 24234451 30021884 physical association cross-linking study IntAct
RGS8 PARP1 24234451 30021884 physical association cross-linking study IntAct
PARP1 SYCP2L 24234451 30021884 physical association cross-linking study IntAct
PARP1 PPARGC1B 24234451 30021884 physical association cross-linking study IntAct
L1TD1 PARP1 24234451 25702638 colocalization,association anti bait coimmunoprecipitation,cosedimentation through density gradient IntAct
KPNA2 PARP1 24234451 25702638 colocalization cosedimentation through density gradient IntAct
RECQL4 PARP1 16949575 27898060 N/A N/A OmniPath
PARP1 SOX2 22362888 27898060 N/A N/A OmniPath
PRKAA2 PARP1 23382195 27898060 N/A N/A OmniPath
CASP1 PARP1 27898060 7642516 N/A N/A OmniPath
MAP3K7 PARP1 15302918 27898060 N/A N/A OmniPath
PARP1 AURKB 16179389 16647857 27898060 inhibition N/A OmniPath
PARP1 KDM5B 20832725 27898060 inhibition N/A OmniPath
PARP1 CHD1L 19661379 19666485 22146311 23926104 27898060 stimulant N/A OmniPath
PARP1 APTX 15044383 15555565 19643912 27898060 stimulant N/A OmniPath
PARP1 H2AZ1 1429884 27898060 stimulant N/A OmniPath
PARP1 TOP1 14699148 15247263 15848144 15911331 17145710 20875401 27898060 inhibition N/A OmniPath
CASP7 PARP1 11058599 11170436 1558065 16374543 18723680 22451931 27898060 9463409 9875225 inhibition N/A OmniPath
PARP1 CASP3 11907276 17167422 18723680 19549685 19713971 22451931 27898060 7596430 8090205 9875225 N/A N/A OmniPath
CASP3 PARP1 10438458 11907276 17167422 18723680 19549685 19713971 22451931 27898060 7596430 7774019 8090205 9875225 inhibition N/A OmniPath
PARP1 H4C1 1429884 27898060 stimulant N/A OmniPath
PARP1 H2BC11 1429884 27898060 stimulant N/A OmniPath
APLF PARP1 17396150 18172500 20098424 26186194 27898060 stimulant N/A OmniPath
PARP1 MRE11 18025084 27898060 stimulant N/A OmniPath
PARP1 ATM 17428792 17459151 18025084 27898060 stimulant N/A OmniPath
SUMO3 PARP1 19622798 27898060 inhibition N/A OmniPath
PARP1 H3C1 1429884 20080577 20504901 27898060 stimulant N/A OmniPath
SUMO1 PARP1 19622798 19779455 27898060 inhibition N/A OmniPath
PARP1 H1-1 18250087 18851700 18927583 27898060 inhibition,stimulant N/A OmniPath
PARP1 RELA 11590148 16204234 16799643 18280497 27898060 N/A N/A OmniPath
EP300 PARP1 12960163 16204234 18280497 19622798 24636898 27898060 stimulant N/A OmniPath
MAPK1 PARP1 16627622 23597856 27898060 stimulant N/A OmniPath
PARP1 TOPBP1 17340632 27898060 N/A N/A OmniPath
PARP1 HIF1A 18314489 27898060 stimulant N/A OmniPath
PARP1 XRCC1 12897160 14500814 15044383 15555565 16713569 18971944 19643912 20302655 20303835 27898060 9584196 9592149 stimulant N/A OmniPath
PARP1 SUPT16H 16682447 18406329 27898060 inhibition,stimulant N/A OmniPath
PARP1 PIAS4 19779455 20696768 20932475 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BAD26 PARP1 27087310 direct interaction,inhibition N/A NPInter

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