GENE:ATP6V1B1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ATP6V1B1 |
| FullNmae | ATPase H+ transporting V1 subunit B1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:853 |
| EnsembleID | ENSG00000116039 |
| Uniprot | P15313 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ATP6V1B1 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ATP6V1B1 | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ATP6V1B1 | GO:0000221,GO:0001503,GO:0003091,GO:0003096,GO:0005515,GO:0005524,GO:0005737,GO:0005829,GO:0005902,GO:0006693,GO:0006885,GO:0007035,GO:0007605,GO:0010468,GO:0015078,GO:0016241,GO:0016323,GO:0016324,GO:0016328,GO:0016471,GO:0030534,GO:0035812,GO:0042048,GO:0042472,GO:0044877,GO:0045851,GO:0046034,GO:0046961,GO:0055064,GO:0055074,GO:0055075,GO:0070062,GO:0070072,GO:0097254,GO:0097401,GO:0098850,GO:1902600 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ATP6V1B1 | hsa:525 | path:hsa00190 | Oxidative phosphorylation - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa04145 | Phagosome - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa04150 | mTOR signaling pathway - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa04721 | Synaptic vesicle cycle - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa04966 | Collecting duct acid secretion - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa05110 | Vibrio cholerae infection - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa05120 | Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
| ATP6V1B1 | hsa:525 | path:hsa05323 | Rheumatoid arthritis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ATP6V1B1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| PRDM14 | ATP6V1B1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CTCF | ATP6V1B1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ATP6V1B1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ATP6V1B1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002394F5 | ATP6V1B1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | ATP6V1B1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F1B8C | ATP6V1B1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | ATP6V1B1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | ATP6V1B1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ATP6V1G1 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| PKP4 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| TFRC | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| FTH1 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| RRAS | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| CD9 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| JUN | ATP6V1B1 | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| SERPINA3 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| SLC9A3R1 | ATP6V1B1 | 10748165 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| ACTN4 | ATP6V1B1 | 10915794 14525934 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| CTSD | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPU | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| S100A11 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| ABCC2 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| RALB | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| SUV39H1 | ATP6V1B1 | 23455924 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| STX1A | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| VAMP8 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| VAMP7 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| STX8 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| SCARB2 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| BANF1 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| NCSTN | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | ATP6V0A1 | 20541250 24234451 25348397 | colocalization | physical interaction,fluorescence microscopy | ComPPI,IntAct |
| ATP6V1B1 | CD63 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | CHMP2B | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | CHMP5 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | DNAJC5 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | MYOF | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | FLOT1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | FLOT2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | GNB1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | IST1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | RAB35 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | TACSTD2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | TMOD3 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | VTI1B | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | HNRNPDL | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | TRMT1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | VPS33B | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | ERGIC1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | LIMA1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | SLC25A3 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | ATP5F1C | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | INTS2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | KDM1A | 23455924 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| ATP6V1B1 | CCT2 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | SVIP | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B1 | SOD1 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| ATP6V1B1 | ATP6V0A4 | 25348397 | N/A | physical interaction | ComPPI |
| RAB22A | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| ATP6V1B2 | ATP6V1B1 | 25348397 | N/A | physical interaction | ComPPI |
| MYH10 | ATP6V1B1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
