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GENE：ATP6V1C2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6V1C2
FullNmae ATPase H+ transporting V1 subunit C2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18264
EnsembleID ENSG00000143882
Uniprot Q8NEY4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6V1C2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V1C2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP6V1C2 GO:0000221,GO:0005765,GO:0005829,GO:0016241,GO:0030177,GO:0042802,GO:0046961,GO:0070062,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6V1C2 hsa:245973 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa04966 Collecting duct acid secretion - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6V1C2 hsa:245973 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 ATP6V1C2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ATP6V1C2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ATP6V1C2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ATP6V1C2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C ATP6V1C2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA ATP6V1C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ATP6V1C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATP6V1C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP6V1C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ATP6V1C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP6V1C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ATP6V1C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
GOLGA2 ATP6V1C2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ATP6V1G1 ATP6V1C2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAGEA2 ATP6V1C2 25348397 N/A physical interaction ComPPI
PDCD10 ATP6V1C2 25348397 N/A physical interaction ComPPI
WASF1 ATP6V1C2 25348397 N/A physical interaction ComPPI
HECTD1 ATP6V1C2 25348397 N/A physical interaction ComPPI
STK24 ATP6V1C2 25348397 N/A physical interaction ComPPI
ECSIT ATP6V1C2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZC3HC1 ATP6V1C2 25348397 N/A physical interaction ComPPI
ATP6V1B2 ATP6V1C2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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