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GENE：ATP6V1E2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP6V1E2
FullNmae ATPase H+ transporting V1 subunit E2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18125
EnsembleID ENSG00000250565
Uniprot Q96A05

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP6V1E2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP6V1E2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP6V1E2 GO:0001669,GO:0005515,GO:0005829,GO:0016241,GO:0033178,GO:0046961,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP6V1E2 hsa:90423 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa04145 Phagosome - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa04721 Synaptic vesicle cycle - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa04966 Collecting duct acid secretion - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
ATP6V1E2 hsa:90423 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 ATP6V1E2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ATP6V1E2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ATP6V1E2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ATP6V1E2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATP6V1E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001938D9 ATP6V1E2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ATP6V1G1 ATP6V1E2 21516116 24234451 25348397 25416956 30021884 physical association two hybrid,cross-linking study,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATP6V1E2 MESD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPT ATP6V1E2 24234451 26402096 association anti bait coimmunoprecipitation IntAct

Source Target Pmid Interactiontype Methods Database
URS00008C0642 ATP6V1E2 27087310 direct interaction,inhibition N/A NPInter

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