Gene Information gene info

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GENE：EXOC8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EXOC8
FullNmae exocyst complex component 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24659
EnsembleID ENSG00000116903
Uniprot Q8IYI6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EXOC8 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EXOC8 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
EXOC8 GO:0000145,GO:0000145,GO:0000145,GO:0000281,GO:0005515,GO:0005770,GO:0005829,GO:0005886,GO:0006887,GO:0006893,GO:0006904,GO:0007032,GO:0008104,GO:0015031,GO:0016020,GO:0016241,GO:0022617,GO:0030426,GO:0031252,GO:0031267,GO:0031267,GO:0035091,GO:0048471,GO:0090148,GO:0090522

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
USHBP1 EXOC8 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 EXOC8 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 EXOC8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA EXOC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EXOC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EXOC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EXOC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D EXOC8 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00002971AB EXOC8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 EXOC8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003E6EFA EXOC8 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D EXOC8 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 EXOC8 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F EXOC8 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C EXOC8 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001C308D EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000157026 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001C4762 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000045E0EC EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EB9FC EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004900F1 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005194EC EXOC8 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B EXOC8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 EXOC8 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EXOC5 EXOC8 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
TBC1D22B EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GOLGA2 EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT18 EXOC8 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KRT19 EXOC8 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
TRIM21 EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIMP2 EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NDC80 EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PBX4 EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT20 EXOC8 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PPFIA1 EXOC8 25348397 N/A physical interaction ComPPI
KRT31 EXOC8 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EXOC8 RALA 11406615 14525934 14525976 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
EXOC8 EXOC2 14525934 14525976 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
EXOC8 KRT15 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EXOC8 TADA2A 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EXOC8 HGS 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EXOC8 CCDC85B 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EXOC8 USHBP1 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
EXOC8 BLOC1S6 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
EXOC8 PCM1 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
EXOC8 RALB 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOC8 ELAVL1 25348397 N/A physical interaction ComPPI
EXOC8 LNX1 25348397 N/A physical interaction ComPPI
EXOC8 EXOC4 21241894 24234451 25348397 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 EXOC3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 TLN2 25348397 N/A physical interaction ComPPI
EXOC8 DHX34 25348397 N/A physical interaction ComPPI
EXOC8 EFHC2 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach ComPPI,IntAct
EXOC8 RAB3IL1 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach ComPPI,IntAct
EXOC8 MBIP 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach ComPPI,IntAct
EXOC8 EGFR 24234451 25348397 25594178 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOC8 RUBCN 25348397 N/A physical interaction ComPPI
EXOC8 ATG14 25348397 N/A physical interaction ComPPI
EXOC8 BECN1 21241894 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
EXOC8 PIK3C3 25348397 N/A physical interaction ComPPI
EXOC8 ULK1 25348397 N/A physical interaction ComPPI
EXOC8 IKZF3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EXOC8 CEP57L1 25348397 N/A physical interaction ComPPI
EXOC8 CEACAM21 25348397 N/A physical interaction ComPPI
EXOC8 CA14 25348397 N/A physical interaction ComPPI
EXOC8 SCN2B 25348397 N/A physical interaction ComPPI
EXOC8 OLFM4 25348397 N/A physical interaction ComPPI
EXOC8 TRARG1 25348397 N/A physical interaction ComPPI
EXOC8 EXOC6 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 EXOC6B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 EXOC7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 NTRK1 25348397 N/A physical interaction ComPPI
EXOC8 SH3BP1 25348397 N/A physical interaction ComPPI
EXOC8 EXOC1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 IL1R2 25348397 N/A physical interaction ComPPI
EXOC8 LRRC41 25348397 N/A physical interaction ComPPI
EXOC8 EHD4 25348397 N/A physical interaction ComPPI
EXOC8 SLC27A2 25348397 N/A physical interaction ComPPI
EXOC8 BNIP1 25348397 N/A physical interaction ComPPI
EXOC8 EPHA1 25348397 N/A physical interaction ComPPI
EXOC8 EHD1 25348397 N/A physical interaction ComPPI
EXOC8 OCIAD1 25348397 N/A physical interaction ComPPI
EXOC8 SIGLECL1 25348397 N/A physical interaction ComPPI
EXOC8 RAB8A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC8 CFTR 25348397 N/A physical interaction ComPPI
EXOC8 WASHC1 24234451 24344185 25348397 physical association anti bait coimmunoprecipitation,two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
EXOC8 CTTN 24234451 24344185 25348397 colocalization fluorescence microscopy ComPPI,IntAct
EXOC8 VPS37B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 TRIM14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 ESS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 TFIP11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 NUP54 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 ATP23 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 STMN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 SNAPC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 SYCE1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 MIPOL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 NAB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 GTF2E2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 BLZF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 MYOZ3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 BLOC1S2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 RINT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 BICRAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 TRIM54 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 GRAMD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 MARCHF7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 ZNF35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 MBD3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 TRIM27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 ELL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 KRT76 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 LZTS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 INSM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 IHO1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 PRR35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 ISY1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOC8 RUSC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BORCS6 EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZC2HC1A EXOC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CPNE3 EXOC8 24234451 30021884 physical association cross-linking study IntAct
MRPS15 EXOC8 24234451 30021884 physical association cross-linking study IntAct
RPS9 EXOC8 24234451 30021884 physical association cross-linking study IntAct

Visualization










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