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GENE：FEZ2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FEZ2
FullNmae fasciculation and elongation protein zeta 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3660
EnsembleID ENSG00000171055
Uniprot Q9UHY8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FEZ2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEZ2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FEZ2 GO:0005515,GO:0005737,GO:0007165,GO:0007399,GO:0007411,GO:0030424,GO:1902902

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NEK1 FEZ2 14690447 23180781 physical association two hybrid,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR FEZ2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 FEZ2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 FEZ2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 FEZ2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FEZ2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA FEZ2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F FEZ2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 FEZ2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 FEZ2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 FEZ2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 FEZ2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000338542 FEZ2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F FEZ2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000072E4C FEZ2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 FEZ2 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SAP30L FEZ2 25361965 interaction type N/A PTMCode2
FEZ2 SAP30L 25361965 interaction type N/A PTMCode2
PRKCZ FEZ2 25361965 interaction type N/A PTMCode2
FEZ2 PRKCZ 25361965 interaction type N/A PTMCode2
DRAP1 FEZ2 25361965 interaction type N/A PTMCode2
FEZ2 DRAP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KPNA2 FEZ2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FEZ1 FEZ2 14525934 16484223 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PRKCZ FEZ2 14525934 14697253 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FEZ2 NEK1 14525934 14690447 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
FEZ2 RAI14 25348397 N/A physical interaction ComPPI
FEZ2 ZNF251 25348397 N/A physical interaction ComPPI
FEZ2 SMC3 25348397 N/A physical interaction ComPPI
FEZ2 PDCD7 25348397 N/A physical interaction ComPPI
FEZ2 SAP30L 25348397 N/A physical interaction ComPPI
FEZ2 CLASP2 25348397 N/A physical interaction ComPPI
FEZ2 WWC1 25348397 N/A physical interaction ComPPI
FEZ2 DRAP1 25348397 N/A physical interaction ComPPI
FEZ2 RAB3GAP1 25348397 N/A physical interaction ComPPI
FEZ2 SCOC 25348397 N/A physical interaction ComPPI
FEZ2 BRD1 25348397 N/A physical interaction ComPPI
FEZ2 TLK2 25348397 N/A physical interaction ComPPI
FEZ2 TEDC2 25348397 N/A physical interaction ComPPI
FEZ2 TBC1D25 25348397 N/A physical interaction ComPPI
FEZ2 ZDHHC17 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping ComPPI,IntAct
FEZ2 DIRAS3 25348397 N/A physical interaction ComPPI
FEZ2 KIF6 25348397 N/A physical interaction ComPPI
FEZ2 MRPS7 25348397 N/A physical interaction ComPPI
FEZ2 PPM1B 25348397 N/A physical interaction ComPPI
FEZ2 TRMT2A 25348397 N/A physical interaction ComPPI
FEZ2 TRIM25 25348397 N/A physical interaction ComPPI

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