Gene Information gene info

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GENE：IFNA14

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFNA14
FullNmae interferon alpha 14
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5420
EnsembleID ENSG00000228083
Uniprot P01570

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFNA14 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IFNA14 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IFNA14 GO:0002250,GO:0002286,GO:0002323,GO:0005125,GO:0005126,GO:0005132,GO:0005515,GO:0005576,GO:0005615,GO:0006959,GO:0019221,GO:0030183,GO:0033141,GO:0042100,GO:0043330,GO:0051607,GO:0060337,GO:0098586

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IFNA14 hsa:3448 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04217 Necroptosis - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05152 Tuberculosis - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05160 Hepatitis C - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05161 Hepatitis B - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05162 Measles - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05164 Influenza A - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05200 Pathways in cancer - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05320 Autoimmune thyroid disease - Homo sapiens (human)
IFNA14 hsa:3448 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF3 IFNA14 16014923 19349300 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
IRF7 IFNA14 10938111 15699120 16014923 16537619 19349300 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility shift assay InnateDB
CREBBP IFNA14 19349300 23180781 physical association anti tag coimmunoprecipitation InnateDB
EP300 IFNA14 19349300 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF5 IFNA14 11303025 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
IRF1 IFNA14 15699120 23180781 physical association affinity chromatography technology InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 IFNA14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IFNA14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IFNA14 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
IFIT3 IFNA14 25348397 N/A physical interaction ComPPI
ISG15 IFNA14 25348397 N/A physical interaction ComPPI
PLAT IFNA14 25348397 N/A physical interaction ComPPI
STIM1 IFNA14 25348397 N/A physical interaction ComPPI
IFIT1 IFNA14 25348397 N/A physical interaction ComPPI
IFNA1 IFNA14 25348397 N/A physical interaction ComPPI
IFNA5 IFNA14 25348397 N/A physical interaction ComPPI
IFNA14 IFNA6 25348397 N/A physical interaction ComPPI
IFNA14 IFNA21 25348397 N/A physical interaction ComPPI
IFNA14 IFNAR1 21856167 27898060 N/A N/A OmniPath
IFNA14 IFNAR2 21856167 27898060 N/A N/A OmniPath

Visualization










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