Gene Information gene info

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GENE：IFNA21

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFNA21
FullNmae interferon alpha 21
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5424
EnsembleID ENSG00000137080
Uniprot P01568

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFNA21 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IFNA21 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IFNA21 GO:0002250,GO:0002286,GO:0002323,GO:0005125,GO:0005126,GO:0005132,GO:0005576,GO:0005615,GO:0006959,GO:0019221,GO:0030183,GO:0033141,GO:0042100,GO:0043330,GO:0051607,GO:0060337,GO:0098586

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IFNA21 hsa:3452 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04217 Necroptosis - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05152 Tuberculosis - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05160 Hepatitis C - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05161 Hepatitis B - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05162 Measles - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05164 Influenza A - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05200 Pathways in cancer - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05320 Autoimmune thyroid disease - Homo sapiens (human)
IFNA21 hsa:3452 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TP53 IFNA21 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 IFNA21 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
IFIT3 IFNA21 25348397 N/A physical interaction ComPPI
ISG15 IFNA21 25348397 N/A physical interaction ComPPI
COL4A2 IFNA21 25348397 N/A physical interaction ComPPI
ADAMTS1 IFNA21 25348397 N/A physical interaction ComPPI
IFIT1 IFNA21 25348397 N/A physical interaction ComPPI
IFNA1 IFNA21 25348397 N/A physical interaction ComPPI
LRFN1 IFNA21 25348397 N/A physical interaction ComPPI
IFNA4 IFNA21 25348397 N/A physical interaction ComPPI
MSRB3 IFNA21 25348397 N/A physical interaction ComPPI
IFNA14 IFNA21 25348397 N/A physical interaction ComPPI
IFNA21 IFNAR1 21856167 27898060 N/A N/A OmniPath
IFNA21 IFNAR2 21856167 27898060 N/A N/A OmniPath

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