Gene Information gene info

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GENE：IFNA4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFNA4
FullNmae interferon alpha 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5425
EnsembleID ENSG00000236637
Uniprot P05014

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFNA4 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IFNA4 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IFNA4 GO:0002250,GO:0002286,GO:0002323,GO:0005125,GO:0005132,GO:0005515,GO:0005576,GO:0005615,GO:0006959,GO:0009615,GO:0019221,GO:0030183,GO:0033141,GO:0042100,GO:0043330,GO:0051607,GO:0060337,GO:0098586

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IFNA4 hsa:3441 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04217 Necroptosis - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05152 Tuberculosis - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05160 Hepatitis C - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05161 Hepatitis B - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05162 Measles - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05164 Influenza A - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05200 Pathways in cancer - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05320 Autoimmune thyroid disease - Homo sapiens (human)
IFNA4 hsa:3441 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IFI16 IFNA4 23180781 25002588 physical association affinity chromatography technology InnateDB
ALDOA IFNA4 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
TNNI3 IFNA4 25348397 N/A physical interaction ComPPI
IFNA4 ALDOA 25348397 N/A physical interaction ComPPI
IFNA4 IFNA5 25348397 N/A physical interaction ComPPI
IFNA4 IFNA21 25348397 N/A physical interaction ComPPI
IFNA4 IFNA7 25348397 N/A physical interaction ComPPI
IFNA4 IFNA8 25348397 N/A physical interaction ComPPI
IFNA4 IFNA1 25348397 N/A physical interaction ComPPI
IFNA4 IFNA2 25348397 N/A physical interaction ComPPI
IFNA4 ISG15 25348397 N/A physical interaction ComPPI
IFNA4 RECK 25348397 N/A physical interaction ComPPI
IFNA4 IFNAR1 21856167 27898060 N/A N/A OmniPath
IFNA4 IFNAR2 21856167 27898060 N/A N/A OmniPath

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