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GENE：MTMR8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MTMR8
FullNmae myotubularin related protein 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16825
EnsembleID ENSG00000102043
Uniprot Q96EF0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MTMR8 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MTMR8 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MTMR8 GO:0004438,GO:0005515,GO:0005635,GO:0005635,GO:0005737,GO:0005737,GO:0005829,GO:0016241,GO:0046856,GO:0052629,GO:0106018

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MTMR8 hsa:55613 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
MTMR8 hsa:55613 path:hsa01100 Metabolic pathways - Homo sapiens (human)
MTMR8 hsa:55613 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 MTMR8 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 MTMR8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MTMR8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MTMR8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
NUDT21 MTMR8 25348397 N/A physical interaction ComPPI
CUL5 MTMR8 25348397 N/A physical interaction ComPPI
ACTB MTMR8 25348397 N/A physical interaction ComPPI
TUFM MTMR8 25348397 N/A physical interaction ComPPI
RNF7 MTMR8 25348397 N/A physical interaction ComPPI
SFPQ MTMR8 25348397 N/A physical interaction ComPPI
PFN1 MTMR8 25348397 N/A physical interaction ComPPI
PFN2 MTMR8 25348397 N/A physical interaction ComPPI
STIP1 MTMR8 25348397 N/A physical interaction ComPPI
RBM10 MTMR8 25348397 N/A physical interaction ComPPI
EGFR MTMR8 25348397 N/A physical interaction ComPPI
ELOB MTMR8 25348397 N/A physical interaction ComPPI
ELOC MTMR8 25348397 N/A physical interaction ComPPI
PRDX6 MTMR8 25348397 N/A physical interaction ComPPI
CARM1 MTMR8 25348397 N/A physical interaction ComPPI
CDK4 MTMR8 25348397 N/A physical interaction ComPPI
DHX38 MTMR8 25348397 N/A physical interaction ComPPI
KRT8 MTMR8 25348397 N/A physical interaction ComPPI
RCN2 MTMR8 25348397 N/A physical interaction ComPPI
SRRT MTMR8 25348397 N/A physical interaction ComPPI
MTMR8 MYH10 25348397 N/A physical interaction ComPPI
MTMR8 RPL38 25348397 N/A physical interaction ComPPI
MTMR8 MTHFD1L 25348397 N/A physical interaction ComPPI
MTMR8 DHX36 25348397 N/A physical interaction ComPPI
MTMR8 PFKFB3 25348397 N/A physical interaction ComPPI
MTMR8 FGG 25348397 N/A physical interaction ComPPI
MTMR8 AIFM1 25348397 N/A physical interaction ComPPI
MTMR8 GLO1 25348397 N/A physical interaction ComPPI
MTMR8 TUBB6 25348397 N/A physical interaction ComPPI
MTMR8 TXNDC5 25348397 N/A physical interaction ComPPI
MTMR8 TAB1 25348397 N/A physical interaction ComPPI
MTMR8 AATK 25348397 N/A physical interaction ComPPI
MTMR8 ERBB3 25348397 N/A physical interaction ComPPI

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