GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
PARL |
| FullNmae |
presenilin associated rhomboid like |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:18253 |
| EnsembleID |
ENSG00000175193 |
| Uniprot |
Q9H300 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| PARL |
autophagy |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
| PARL |
apoptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| PARL |
GO:0004175,GO:0004175,GO:0004175,GO:0004252,GO:0004252,GO:0005515,GO:0005634,GO:0005739,GO:0005743,GO:0006465,GO:0006508,GO:0006508,GO:0008053,GO:0010821,GO:0030162,GO:0033619,GO:0033619,GO:0033619,GO:0090201,GO:1903146,GO:1903214,GO:1903214,GO:2000377,GO:2001243 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
PARL |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
PARL |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
PARL |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
PARL |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
PARL |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
PARL |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
PARL |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| SPI1 |
PARL |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| TAL1 |
PARL |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00000FC8EB |
PARL |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00004AC389 |
PARL |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS000016D2D4 |
PARL |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00000C85B2 |
PARL |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00003BD367 |
PARL |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000076B539 |
PARL |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000042619A |
PARL |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000101787 |
PARL |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000472A9B |
PARL |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| SLC7A1 |
PARL |
25348397
|
N/A |
physical interaction |
ComPPI |
| ENAH |
PARL |
25348397
|
N/A |
physical interaction |
ComPPI |
| RBFOX2 |
PARL |
25348397
|
N/A |
physical interaction |
ComPPI |
| BSG |
PARL |
25348397
|
N/A |
physical interaction |
ComPPI |
| H2AC21 |
PARL |
25348397
|
N/A |
physical interaction |
ComPPI |
| PINK1 |
PARL |
25348397
|
N/A |
physical interaction |
ComPPI |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00009BA719 |
PARL |
27087310
|
direct interaction,inhibition |
N/A |
NPInter |
Visualization