Gene Information gene info

GENE:POLR3A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLR3A
FullNmae RNA polymerase III subunit A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30074
EnsembleID ENSG00000148606
Uniprot O14802

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLR3A autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
POLR3A GO:0001056,GO:0003677,GO:0003682,GO:0003899,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005666,GO:0005666,GO:0005829,GO:0006351,GO:0006383,GO:0016020,GO:0032728,GO:0045087,GO:0046872,GO:0051607

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POLR3A hsa:11128 path:hsa03020 RNA polymerase - Homo sapiens (human)
POLR3A hsa:11128 path:hsa04623 Cytosolic DNA-sensing pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
POLR3G POLR3A 19631370 23180781 physical association tandem affinity purification InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 POLR3A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 POLR3A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 POLR3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 POLR3A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F POLR3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 POLR3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC POLR3A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 POLR3A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001D6605 POLR3A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 POLR3A 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 POLR3A 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 POLR3A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B POLR3A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 POLR3A 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000122F23 POLR3A 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075B538 POLR3A 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
POLR2J POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR2J 25361965 interaction type N/A PTMCode2
POLR2L POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR2L 25361965 interaction type N/A PTMCode2
GTF2B POLR3A 25361965 interaction type N/A PTMCode2
POLR3A GTF2B 25361965 interaction type N/A PTMCode2
POLR3A POLR3F 25361965 interaction type N/A PTMCode2
POLR3F POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR3G 25361965 interaction type N/A PTMCode2
POLR3G POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR2F 25361965 interaction type N/A PTMCode2
POLR2F POLR3A 25361965 interaction type N/A PTMCode2
POLR3E POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR3E 25361965 interaction type N/A PTMCode2
POLR2B POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR2B 25361965 interaction type N/A PTMCode2
POLR1B POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR1B 25361965 interaction type N/A PTMCode2
POLR2E POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR2E 25361965 interaction type N/A PTMCode2
POLR2C POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR2C 25361965 interaction type N/A PTMCode2
RPL30 POLR3A 25361965 interaction type N/A PTMCode2
POLR3A RPL30 25361965 interaction type N/A PTMCode2
POLR2G POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR2G 25361965 interaction type N/A PTMCode2
POLR1D POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR1D 25361965 interaction type N/A PTMCode2
PKP2 POLR3A 25361965 interaction type N/A PTMCode2
POLR3A PKP2 25361965 interaction type N/A PTMCode2
POLR3D POLR3A 25361965 interaction type N/A PTMCode2
POLR3A POLR3D 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1CC POLR3A 25348397 N/A physical interaction ComPPI
NUDCD3 POLR3A 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
UXT POLR3A 25348397 N/A physical interaction ComPPI
PCBD1 POLR3A 25348397 N/A physical interaction ComPPI
POLR3C POLR3A 25348397 N/A physical interaction ComPPI
KEAP1 POLR3A 25348397 N/A physical interaction ComPPI
GTF2B POLR3A 25348397 N/A physical interaction ComPPI
TUFM POLR3A 25348397 N/A physical interaction ComPPI
SKAP1 POLR3A 25348397 N/A physical interaction ComPPI
NTRK1 POLR3A 25348397 N/A physical interaction ComPPI
CDH5 POLR3A 25348397 N/A physical interaction ComPPI
PKP2 POLR3A 11416169 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
RUVBL1 POLR3A 25348397 N/A physical interaction ComPPI
SMARCA4 POLR3A 25348397 N/A physical interaction ComPPI
PTGES3 POLR3A 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
PPP1CA POLR3A 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MYC POLR3A 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
KSR2 POLR3A 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
EWSR1 POLR3A 25348397 N/A physical interaction ComPPI
CHM POLR3A 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC2 POLR3A 25348397 N/A physical interaction ComPPI
POLR3E POLR3A 12391170 14525934 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
POLR3D POLR3A 25348397 N/A physical interaction ComPPI
URI1 POLR3A 25348397 N/A physical interaction ComPPI
POLR2E POLR3A 25348397 N/A physical interaction ComPPI
POLR2A POLR3A 25348397 N/A physical interaction ComPPI
GPN1 POLR3A 25348397 N/A physical interaction ComPPI
NEDD4 POLR3A 25348397 N/A physical interaction ComPPI
GTF3C3 POLR3A 25348397 N/A physical interaction ComPPI
RAE1 POLR3A 25348397 N/A physical interaction ComPPI
SMARCA5 POLR3A 25348397 N/A physical interaction ComPPI
POLR1A POLR3A 25348397 N/A physical interaction ComPPI
POLR3A RPAP2 25348397 N/A physical interaction ComPPI
POLR3A RPAP3 24234451 25036637 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
POLR3A POLR3H 25348397 N/A physical interaction ComPPI
POLR3A RPAP1 25348397 N/A physical interaction ComPPI
POLR3A IKBKG 25348397 N/A physical interaction ComPPI
POLR3A POLR2H 25348397 N/A physical interaction ComPPI
POLR3A POLR3B 25348397 N/A physical interaction ComPPI
POLR3A POLR1C 25348397 N/A physical interaction ComPPI
POLR3A CRCP 25348397 N/A physical interaction ComPPI
POLR3A POLR1D 25348397 N/A physical interaction ComPPI
POLR3A POLR1D 25348397 N/A physical interaction ComPPI
POLR3A VPS18 25348397 N/A physical interaction ComPPI
POLR3A ASB13 25348397 N/A physical interaction ComPPI
POLR3A MAF1 25348397 N/A physical interaction ComPPI
POLR3A GPN3 25348397 N/A physical interaction ComPPI
POLR3A PIH1D1 25348397 N/A physical interaction ComPPI
POLR3A PPP2R2C 25348397 N/A physical interaction ComPPI
POLR3A EVA1C 25348397 N/A physical interaction ComPPI
POLR3A HDAC1 25348397 N/A physical interaction ComPPI
POLR3A IPO9 25348397 N/A physical interaction ComPPI
POLR3A MRPL17 25348397 N/A physical interaction ComPPI
POLR3A MRPL22 25348397 N/A physical interaction ComPPI
POLR3A MRPL24 25348397 N/A physical interaction ComPPI
POLR3A MRPL54 25348397 N/A physical interaction ComPPI
POLR3A MRPS7 25348397 N/A physical interaction ComPPI
POLR3A POLR1B 25348397 N/A physical interaction ComPPI
POLR3A MRPL11 25348397 N/A physical interaction ComPPI
POLR3A MRPL2 25348397 N/A physical interaction ComPPI
POLR3A POLR2B 25348397 N/A physical interaction ComPPI
POLR3A POLR3F 25348397 N/A physical interaction ComPPI
POLR3A POLR3G 25348397 N/A physical interaction ComPPI
POLR3A POLR3K 25348397 N/A physical interaction ComPPI
POLR3A RPS5 25348397 N/A physical interaction ComPPI
POLR3A TSR1 25348397 N/A physical interaction ComPPI
POLR3A POLR2F 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR3A ASB7 25348397 N/A physical interaction ComPPI
POLR3A RUVBL2 25348397 N/A physical interaction ComPPI
POLR3A ZNHIT2 25348397 N/A physical interaction ComPPI
POLR3A SLC7A6OS 25348397 N/A physical interaction ComPPI
POLR3A DNAAF10 25348397 N/A physical interaction ComPPI
POLR3A PFDN2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
POLR3GL POLR3A 25348397 N/A physical interaction ComPPI

Visualization