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GENE：RALB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RALB
FullNmae RAS like proto-oncogene B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9840
EnsembleID ENSG00000144118
Uniprot P11234

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RALB autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RALB autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RALB GO:0001928,GO:0001934,GO:0003924,GO:0003924,GO:0003925,GO:0005515,GO:0005525,GO:0005525,GO:0005525,GO:0005886,GO:0005886,GO:0006915,GO:0007049,GO:0007165,GO:0007265,GO:0009267,GO:0019003,GO:0019003,GO:0030496,GO:0031623,GO:0031625,GO:0032091,GO:0032092,GO:0045742,GO:0051117,GO:0051301,GO:0060178,GO:0070062,GO:0071360,GO:0071902,GO:2000786

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RALB hsa:5899 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
RALB hsa:5899 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
RALB hsa:5899 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
RALB hsa:5899 path:hsa05200 Pathways in cancer - Homo sapiens (human)
RALB hsa:5899 path:hsa05210 Colorectal cancer - Homo sapiens (human)
RALB hsa:5899 path:hsa05212 Pancreatic cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EXOC2 RALB 17018283 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 RALB 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 RALB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 RALB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RALB 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 RALB 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 RALB 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RALB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 RALB 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000324096 RALB 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PRKCA RALB 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
RALBP1 RALB 14525934 16189514 24234451 25348397 7673236 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid ComPPI,HPRD,IntAct
TPP2 RALB 25348397 N/A physical interaction ComPPI
CALM1 RALB 25348397 N/A pull down,physical interaction ComPPI
EXOC8 RALB 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
MAPK14 RALB 25348397 N/A physical interaction ComPPI
NONO RALB 25348397 N/A physical interaction ComPPI
PAM RALB 25348397 N/A physical interaction ComPPI
LAMTOR3 RALB 25348397 N/A physical interaction ComPPI
XPO5 RALB 25348397 N/A physical interaction ComPPI
EXOC1 RALB 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
REPS1 RALB 14525934 25348397 9422736 N/A experimental interaction detection,in vitro ComPPI,HPRD
EXOC3 RALB 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOC2 RALB 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
EXOC4 RALB 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
REPS2 RALB 14525934 25348397 9422736 N/A experimental interaction detection,in vitro ComPPI,HPRD
RALB PLCD1 14525934 15817490 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
RALB ATP6V1B1 25348397 N/A physical interaction ComPPI
RALB MARCKSL1 25348397 N/A physical interaction ComPPI
RALB PYCARD 22286270 24234451 25348397 colocalization physical interaction,confocal microscopy ComPPI,IntAct
RALB USP33 25348397 N/A physical interaction ComPPI
RALB ULK1 25348397 N/A physical interaction ComPPI
RALB ATG14 25348397 N/A physical interaction ComPPI
RALB UVRAG 25348397 N/A physical interaction ComPPI
RALB ANKRD13A 25348397 N/A physical interaction ComPPI
RALB DBT 25348397 N/A physical interaction ComPPI
RALB HAUS4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RALB OCIAD1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RALB EI24 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RALB HAUS1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RALB TULP3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RALB TRIM25 25348397 N/A physical interaction ComPPI
RALB ATG12 21241894 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RALB ATG5 21241894 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RALB BECN1 21241894 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
RALB ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RALB INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RALB KAT6B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ALDH18A1 RALB 25348397 N/A physical interaction ComPPI
TGIF2LY RALB 25348397 N/A physical interaction ComPPI
RGL4 RALB 12874025 14525934 N/A experimental interaction detection HPRD
RALB CALM2 12034722 14525934 24234451 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,two hybrid HPRD,IntAct
PRKCA RALB 20940393 27898060 N/A N/A OmniPath
RALB RALBP1 14525976 16189514 21241894 21686269 27898060 7673236 9422736 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008B75F7 RALB 27087310 direct interaction,inhibition N/A NPInter

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