Gene Information gene info

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GENE：RRAGB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RRAGB
FullNmae Ras related GTP binding B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19901
EnsembleID ENSG00000083750
Uniprot Q5VZM2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RRAGB autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RRAGB autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RRAGB GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005525,GO:0005634,GO:0005737,GO:0005764,GO:0005764,GO:0005765,GO:0005829,GO:0008104,GO:0009267,GO:0010507,GO:0032006,GO:0032008,GO:0032561,GO:0034198,GO:0051020,GO:0071230,GO:1904263,GO:1990131,GO:1990253

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RRAGB hsa:10325 path:hsa04140 Autophagy - animal - Homo sapiens (human)
RRAGB hsa:10325 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
RRAGB hsa:10325 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RRAGB RRAGD 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB
RPTOR RRAGB 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB
RRAGB MTOR 18497260 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RRAGB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RRAGB 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA RRAGB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RRAGB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RRAGB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RRAGB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RRAGB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RRAGB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 RRAGB 20215506 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
LGALS3 RRAGB 25348397 N/A physical interaction ComPPI
ATP6V1D RRAGB 23394946 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
LAMTOR4 RRAGB 24234451 25348397 25561175 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LGALS9C RRAGB 25348397 N/A physical interaction ComPPI
YWHAB RRAGB 25348397 N/A physical interaction ComPPI
LAMTOR3 RRAGB 20381137 22980980 24234451 25348397 25561175 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SQSTM1 RRAGB 25348397 N/A physical interaction ComPPI
PDHB RRAGB 25348397 N/A physical interaction ComPPI
TSC2 RRAGB 25348397 N/A physical interaction ComPPI
CSE1L RRAGB 25348397 N/A physical interaction ComPPI
LGALS8 RRAGB 25348397 N/A physical interaction ComPPI
LAMP2 RRAGB 23394946 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
MTOR RRAGB 25348397 N/A physical interaction ComPPI
CDH13 RRAGB 25348397 N/A physical interaction ComPPI
TGOLN2 RRAGB 25348397 N/A physical interaction ComPPI
LAMTOR2 RRAGB 20381137 22980980 24234451 25348397 25567906 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPTOR RRAGB 25348397 N/A physical interaction ComPPI
RRAGC RRAGB 11073942 14525934 20381137 22424946 24234451 25348397 25561175 25567906 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RRAGB RRAGD 11073942 14525934 20381137 22424946 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RRAGB APP 25348397 N/A physical interaction ComPPI
RRAGB GSS 25348397 N/A physical interaction ComPPI
RRAGB LAMTOR5 22980980 24234451 25348397 25561175 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGB LAMTOR1 20381137 22980980 24234451 25348397 25561175 25567906 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGB LGALS9 25348397 N/A physical interaction ComPPI
RRAGB CD164L2 25348397 N/A physical interaction ComPPI
RRAGB WDR24 25348397 N/A physical interaction ComPPI
RRAGB DEPDC5 25348397 N/A physical interaction ComPPI
RRAGB FPR2 25348397 N/A physical interaction ComPPI
RRAGB TPCN2 25348397 N/A physical interaction ComPPI
RRAGB NUDT1 25348397 N/A physical interaction ComPPI
RRAGB TRIM16 25348397 N/A physical interaction ComPPI
RRAGB SLC38A9 24234451 25348397 25561175 25567906 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RRAGB LAMP1 23394946 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RRAGB RRAGA 24234451 25348397 25561175 association anti tag coimmunoprecipitation ComPPI,IntAct
CKB RRAGB 25348397 N/A physical interaction ComPPI
BLVRA RRAGB 25348397 N/A physical interaction ComPPI
RRAGB RPTOR 18497260 21981924 24337580 27898060 inhibition N/A OmniPath
RPTOR RRAGB 18497260 21981924 24337580 27898060 N/A N/A OmniPath
RRAGB MTOR 18497260 24337580 27898060 inhibition N/A OmniPath
RRAGD RRAGB 11073942 18497260 20381137 22424946 24337580 27898060 N/A N/A OmniPath

Visualization










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