Gene Information gene info

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GENE：SCFD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SCFD1
FullNmae sec1 family domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20726
EnsembleID ENSG00000092108
Uniprot Q8WVM8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SCFD1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SCFD1 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SCFD1 GO:0000139,GO:0000902,GO:0001666,GO:0005515,GO:0005789,GO:0005798,GO:0005801,GO:0005829,GO:0005886,GO:0006886,GO:0006888,GO:0006890,GO:0006892,GO:0009636,GO:0019905,GO:0019905,GO:0032580,GO:0044877,GO:0051223,GO:0060628,GO:1902902

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SCFD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SCFD1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SCFD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SCFD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SCFD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SCFD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SCFD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SCFD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SCFD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 SCFD1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 SCFD1 25348397 N/A physical interaction ComPPI
VAMP2 SCFD1 25348397 N/A physical interaction ComPPI
VCP SCFD1 25348397 N/A physical interaction ComPPI
LMNA SCFD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MCM2 SCFD1 25348397 N/A physical interaction ComPPI
APPBP2 SCFD1 25348397 N/A physical interaction ComPPI
JUN SCFD1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PDGFRA SCFD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 SCFD1 25348397 N/A physical interaction ComPPI
USO1 SCFD1 25348397 N/A physical interaction ComPPI
CANX SCFD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DNAJA3 SCFD1 25348397 N/A physical interaction ComPPI
SNAP23 SCFD1 25348397 N/A physical interaction ComPPI
EVC2 SCFD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ATP6AP2 SCFD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSF SCFD1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOX2 SCFD1 25348397 N/A physical interaction ComPPI
EGFR SCFD1 25348397 N/A physical interaction ComPPI
OCRL SCFD1 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ILF2 SCFD1 25348397 N/A physical interaction ComPPI
STX5 SCFD1 12506202 14525934 14565970 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
GOSR1 SCFD1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGOLN2 SCFD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STX6 SCFD1 25348397 N/A physical interaction ComPPI
SEC22B SCFD1 25348397 N/A physical interaction ComPPI
SCFD1 DLST 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SCFD1 PPBP 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SCFD1 STX18 19369418 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SCFD1 USP22 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SCFD1 KAT5 25348397 N/A physical interaction ComPPI
SCFD1 LRRK2 17400507 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SCFD1 MRPL13 25348397 N/A physical interaction ComPPI
SCFD1 ATP6V0A1 25348397 N/A physical interaction ComPPI
SCFD1 MRPL49 25348397 N/A physical interaction ComPPI
SCFD1 HSPA6 25348397 N/A physical interaction ComPPI
SCFD1 OGDH 25348397 N/A physical interaction ComPPI
SCFD1 HOOK3 25348397 N/A physical interaction ComPPI
SCFD1 SLC25A3 25348397 N/A physical interaction ComPPI
SCFD1 STAU1 25348397 N/A physical interaction ComPPI
SCFD1 MOV10 25348397 N/A physical interaction ComPPI
SCFD1 NXF1 25348397 N/A physical interaction ComPPI
SCFD1 USE1 19369418 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SCFD1 FBF1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SCFD1 RAB5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SCFD1 VAMP4 25348397 N/A physical interaction ComPPI
SCFD1 MIA3 25348397 N/A physical interaction ComPPI
SCFD1 COG4 19536132 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,competition binding ComPPI,IntAct
SCFD1 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
SCFD1 BET1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
COG7 SCFD1 19536132 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
MRPL15 SCFD1 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009C06DD SCFD1 27087310 direct interaction,inhibition N/A NPInter

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